Abstract
The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along the template RNA. By the use of sequential labeling techniques and exonucleases, it has been determined that there is a 5′ to 3′ direction of product RNA synthesis.
Dates
Type | When |
---|---|
Created | 5 years, 7 months ago (Jan. 5, 2020, 7:14 p.m.) |
Deposited | 3 years, 5 months ago (March 4, 2022, 4:56 p.m.) |
Indexed | 2 years, 3 months ago (May 23, 2023, 2:29 p.m.) |
Issued | 52 years, 5 months ago (April 1, 1973) |
Published | 52 years, 5 months ago (April 1, 1973) |
Published Print | 52 years, 5 months ago (April 1, 1973) |
@article{Roy_1973, title={Initiation and Direction of RNA Transcription by Vesicular Stomatitis Virus Virion Transcriptase}, volume={11}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.11.4.487-501.1973}, DOI={10.1128/jvi.11.4.487-501.1973}, number={4}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Roy, Polly and Bishop, D. H. L.}, year={1973}, month=apr, pages={487–501} }