DOI: 10.1128/jb.178.11.3037-3043.1996. Redundant homosexual F transfer facilitates selection-induced reversion of plasmid mutations

Redundant homosexual F transfer facilitates selection-induced reversion of plasmid mutations

10.1128/jb.178.11.3037-3043.1996

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

F plasmids use surface exclusion to prevent the redundant entry of additional F plasmids during active growth of the host cells. This mechanism is relaxed during stationary phase and nonlethal selections, allowing homosexual redundant plasmid transfer. Homosexual redundant transfer occurs in stationary-phase liquid cultures, within nongrowing populations on solid media, and on media lacking a carbon source. We examined the relationship between homosexual redundant transfer, which occurs between F+ hosts, and reversion of a plasmid-encoded lac mutant allele, lacI33omegalacZ. Sodium dodecyl sulfate (SDS) and mutations that prevent normal transfer to F- cells reduced redundant transfer and selection-induced reversion of the lacI33omegalacZ allele. A recA null mutation reduced redundant transfer and selection-induced reversion of the lacI33omegalacZ mutation. Conversely, a recD null mutation increased redundant transfer and selection-induced reversion of the lacI33omegalacZ allele. These results suggest an explanation for why SDS and these mutations affect reversion of the plasmid lacI33omegalacZ allele. However, a direct causal relationship between transfer and reversion remains to be established. These results suggest that Rec proteins play an active role in redundant transfer and/or that redundant transfer is regulated with the activation of recombination. Redundant homosexual plasmid transfer during a period of stress may represent a genetic response that facilitates evolution of plasmid-encoded functions through mutation, recombination, reassortment, and dissemination of genetic elements present in the populations.

Bibliography

Peters, J. E., Bartoszyk, I. M., Dheer, S., & Benson, S. A. (1996). Redundant homosexual F transfer facilitates selection-induced reversion of plasmid mutations. Journal of Bacteriology, 178(11), 3037â3043.

Authors 4

J E Peters (first)
I M Bartoszyk (additional)
S Dheer (additional)
S A Benson (additional)

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Dates

Type	When
Created	8 years, 9 months ago (Nov. 10, 2016, 7:32 a.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:56 p.m.)
Indexed	1 year, 3 months ago (May 20, 2024, 6:34 p.m.)
Issued	29 years, 3 months ago (June 1, 1996)
Published	29 years, 3 months ago (June 1, 1996)
Published Print	29 years, 3 months ago (June 1, 1996)

Funders 0

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BibTeX

@article{Peters_1996, title={Redundant homosexual F transfer facilitates selection-induced reversion of plasmid mutations}, volume={178}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.178.11.3037-3043.1996}, DOI={10.1128/jb.178.11.3037-3043.1996}, number={11}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Peters, J E and Bartoszyk, I M and Dheer, S and Benson, S A}, year={1996}, month=jun, pages={3037–3043} }

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