DOI: 10.1128/jb.177.11.3308-3311.1995. Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis

Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis

10.1128/jb.177.11.3308-3311.1995

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

We fused obg, encoding an essential GTP-binding protein in Bacillus subtilis, to the LacI-repressible, IPTG (isopropyl-beta-D-thiogalactopyranoside)-inducible promoter Pspac. Depletion of Obg, following removal of IPTG, caused a defect in sporulation and in expression of sporulation genes that are activated by Spo0A approximately P. These defects were significantly relieved by a mutation in spo0A (rvtA11) that bypasses the normal phosphorylation pathway, indicating that Obg might normally be required, either directly or indirectly, to stimulate activity of the phosphorelay that activates Spo0A.

Bibliography

Vidwans, S. J., Ireton, K., & Grossman, A. D. (1995). Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis. Journal of Bacteriology, 177(11), 3308â3311.

Authors 3

S J Vidwans (first)
K Ireton (additional)
A D Grossman (additional)

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Dates

Type	When
Created	8 years, 9 months ago (Nov. 14, 2016, 12:16 p.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:49 p.m.)
Indexed	2 months ago (July 2, 2025, 2:36 p.m.)
Issued	30 years, 3 months ago (June 1, 1995)
Published	30 years, 3 months ago (June 1, 1995)
Published Print	30 years, 3 months ago (June 1, 1995)

Funders 0

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BibTeX

@article{Vidwans_1995, title={Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis}, volume={177}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.177.11.3308-3311.1995}, DOI={10.1128/jb.177.11.3308-3311.1995}, number={11}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Vidwans, S J and Ireton, K and Grossman, A D}, year={1995}, month=jun, pages={3308–3311} }

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