DOI: 10.1128/jb.175.17.5505-5509.1993. Degradation of individual chromosomes in recA mutants of Escherichia coli

Degradation of individual chromosomes in recA mutants of Escherichia coli

10.1128/jb.175.17.5505-5509.1993

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

Rapidly growing wild-type Escherichia coli cells contain two, four, or eight fully replicated chromosomes after treatment with rifampin, reflecting that all replication origins are initiated simultaneously. Cells with defects in the timing of the initiation of replication may contain three, five, six, or seven fully replicated chromosomes after such treatment. This phenotype, termed the asynchrony phenotype, is also seen in recombination-deficient recA mutants. It is shown here that for recA strains, the phenotype can be explained by a selective and complete degradation of individual chromosomes. The selective degradation is largely recD dependent and is thus carried out by the RecBCD exonuclease.

Bibliography

Skarstad, K., & Boye, E. (1993). Degradation of individual chromosomes in recA mutants of Escherichia coli. Journal of Bacteriology, 175(17), 5505â5509.

Authors 2

K Skarstad (first)
E Boye (additional)

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Dates

Type	When
Created	8 years, 9 months ago (Nov. 7, 2016, 3:22 p.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:52 p.m.)
Indexed	1 week ago (Aug. 23, 2025, 9:37 p.m.)
Issued	31 years, 11 months ago (Sept. 1, 1993)
Published	31 years, 11 months ago (Sept. 1, 1993)
Published Print	31 years, 11 months ago (Sept. 1, 1993)

Funders 0

None

BibTeX

@article{Skarstad_1993, title={Degradation of individual chromosomes in recA mutants of Escherichia coli}, volume={175}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.175.17.5505-5509.1993}, DOI={10.1128/jb.175.17.5505-5509.1993}, number={17}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Skarstad, K and Boye, E}, year={1993}, month=sep, pages={5505–5509} }

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