DOI: 10.1128/jb.173.6.2006-2010.1991. A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase

A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase

10.1128/jb.173.6.2006-2010.1991

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

A temperature-sensitive mutant of Saccharomyces cerevisiae was identified which at the restrictive temperature of 37 degrees C is unable to secrete a number of cell wall-associated proteins and thus resembles previously reported sec mutants. In contrast to other sec mutants, however, both the temperature-sensitive growth and the secretion defects can be repaired by the addition of D-mannose to growth media. We show that the mutant possesses a single, apparently recessive mutation which leads to the production of a thermolabile phosphomannose isomerase.

Bibliography

Payton, M. A., Rheinnecker, M., Klig, L. S., DeTiani, M., & Bowden, E. (1991). A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase. Journal of Bacteriology, 173(6), 2006â2010.

Authors 5

M A Payton (first)
M Rheinnecker (additional)
L S Klig (additional)
M DeTiani (additional)
E Bowden (additional)

References 17 Referenced 55

Bainbridge B. W. B. P. Valentine and P. Markham. 1979. The use of temperature-sensitive mutants to study wall growth p. 71-91. In J. H. Burnett and A. P. J. Trinci (ed.) Fungal walls and hyphal growth. Cambridge University Press Cambridge.
Conzelmann , A. , C. Fankhauser , and C. Desponds . 1990 . Myoinositol gets incorporated into numerous membrane glycoproteins in Saccharomyces cerevisiae; incorporation is dependent on phosphomannomutase (sec 53) . EMBO J. 9 : 653 - 661 . (10.1002/j.1460-2075.1990.tb08157.x) / EMBO J. / Myoinositol gets incorporated into numerous membrane glycoproteins in Saccharomyces cerevisiae; incorporation is dependent on phosphomannomutase (sec 53) by Conzelmann A. (1990)
Frevert , J. , and C. Baliou . 1985 . Saccharomyces cerevisiae structural cell wall mannoprotein . Biochemistry 24 : 753 - 759 . (10.1021/bi00324a033) / Biochemistry / Saccharomyces cerevisiae structural cell wall mannoprotein by Frevert J. (1985)
Hartwell , L. H. 1967 . Macromolecular synthesis in temperaturesensitive mutants of yeast . J. Bacteriol. 93 : 1662 - 1670 . (10.1128/jb.93.5.1662-1670.1967) / J. Bacteriol. / Macromolecular synthesis in temperaturesensitive mutants of yeast by Hartwell L. H. (1967)
Herrera , L. S. , C. Pascual , and X. Alvarez . 1976 . Genetic and biochemical studies of phosphomannose isomerase deficient mutants of Saccharomyces cerevisiae . Mol. Gen. Genet. 144 : 223 - 230 . (10.1007/BF02428113) / Mol. Gen. Genet. / Genetic and biochemical studies of phosphomannose isomerase deficient mutants of Saccharomyces cerevisiae by Herrera L. S. (1976)
Herrero , E. , and R. Sentandreu . 1988 . Protein secretion and compartmentalisation in yeast . Microbiol. Semin. 4 : 73 - 85 . / Microbiol. Semin. / Protein secretion and compartmentalisation in yeast by Herrero E. (1988)
Huffaker , T. C. , and P. W. Robbins . 1982 . Temperature-sensitive yeast mutants deficient in asparagine-linked glycosylation . J. Biol. Chem. 257 : 3203 - 3210 . (10.1016/S0021-9258(19)81096-7) / J. Biol. Chem. / Temperature-sensitive yeast mutants deficient in asparagine-linked glycosylation by Huffaker T. C. (1982)
Kepes , F. , and R. Schekman . 1988 . The yeast secS3 gene encodes phosphomannomutase . J. Biol. Chem. 263 : 9155 - 9161 . (10.1016/S0021-9258(19)76520-X) / J. Biol. Chem. / The yeast secS3 gene encodes phosphomannomutase by Kepes F. (1988)
Klyce , H. R. , and C. S. Mclaughlin . 1973 . Characterisation of temperature-sensitive mutants of yeast by a photomicrographic procedure . Exp. Cell Res. 82 : 47 - 56 . (10.1016/0014-4827(73)90243-7) / Exp. Cell Res. / Characterisation of temperature-sensitive mutants of yeast by a photomicrographic procedure by Klyce H. R. (1973)
Novick , P. , S. Ferro , and R. Schekman . 1981 . Order of events in the yeast secretory pathway . Cell 25 : 461 - 469 . (10.1016/0092-8674(81)90064-7) / Cell / Order of events in the yeast secretory pathway by Novick P. (1981)
Novick , P. , C. Field , and R. Schekman . 1980 . Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway . Cell 21 : 205 - 215 . (10.1016/0092-8674(80)90128-2) / Cell / Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway by Novick P. (1980)
Novick , P. , and R. Schekman . 1979 . Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae . Proc. Nat. Acad. Sci. USA 76 : 1858 - 1862 . (10.1073/pnas.76.4.1858) / Proc. Nat. Acad. Sci. USA / Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae by Novick P. (1979)
Novick , P. , and R. Schekman . 1983 . Export of major cell surface proteins is blocked in yeast secretory mutants . J. Cell Biol. 96 : 541 - 547 . (10.1083/jcb.96.2.541) / J. Cell Biol. / Export of major cell surface proteins is blocked in yeast secretory mutants by Novick P. (1983)
Schekman , R. 1985 . Protein localisation and membrane traffic in yeast. Annu . Rev. Cell Biol. 1 : 115 - 143 . (10.1146/annurev.cb.01.110185.000555) / Rev. Cell Biol. / Protein localisation and membrane traffic in yeast. Annu by Schekman R. (1985)
Schekman R. Personal communication.
Sherman F. G. R. Fink and J. B. Hicks (ed.). 1982. Methods in yeast genetics: a laboratory manual. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.
Valentin , E. , E. Herrero , F. I. J. Pastor , and R. Sentandreu . 1984 . Solubilisation and analysis of mannoprotein molecules from the cell wall of Saccharomyces cerevisiae . J. Gen. Microbiol. 130 : 1419 - 1428 . / J. Gen. Microbiol. / Solubilisation and analysis of mannoprotein molecules from the cell wall of Saccharomyces cerevisiae by Valentin E. (1984)

Dates

Type	When
Created	8 years, 9 months ago (Nov. 4, 2016, 1:52 p.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:13 p.m.)
Indexed	1 year, 1 month ago (July 5, 2024, 12:35 p.m.)
Issued	34 years, 6 months ago (March 1, 1991)
Published	34 years, 6 months ago (March 1, 1991)
Published Print	34 years, 6 months ago (March 1, 1991)

Funders 0

None

BibTeX

@article{Payton_1991, title={A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase}, volume={173}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.173.6.2006-2010.1991}, DOI={10.1128/jb.173.6.2006-2010.1991}, number={6}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Payton, M A and Rheinnecker, M and Klig, L S and DeTiani, M and Bowden, E}, year={1991}, month=mar, pages={2006–2010} }

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