Cell shape and division in Escherichia coli: experiments with shape and division mutants
10.1128/jb.163.2.615-622.1985
Crossref journal-article
American Society for Microbiology
Journal of Bacteriology (235)
Abstract

Double mutants which carry mutations in genes (rodA, pbpA) required for cell elongation (i.e., maintenance of rod shape) in combination with mutations in genes (ftsA, ftsI, ftsQ, or ftsZ) required for septation were constructed. Such mutants were able to grow for about two mass doublings at a normal rate at the restrictive temperature (42 degrees C). The morphology of the cells formed under these conditions was interpreted by assuming the existence of a generalized system for peptidoglycan growth together with two additional systems which modify the shape of the growing peptidoglycan layer. The results also showed that different fts genes probably control different stages in septation. ftsZ (sulB or sfiB) appears to be required for the earliest step in septation, ftsQ and ftsI (pbpB or sep) are required for a later step or steps, and ftsA is required only for the latest stages in septation.

Bibliography

Begg, K. J., & Donachie, W. D. (1985). Cell shape and division in Escherichia coli: experiments with shape and division mutants. Journal of Bacteriology, 163(2), 615–622.

Authors 2
  1. K J Begg (first)
  2. W D Donachie (additional)
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Dates
Type When
Created 5 years, 7 months ago (Jan. 3, 2020, 1:19 p.m.)
Deposited 4 years ago (July 29, 2021, 1:30 p.m.)
Indexed 2 months, 2 weeks ago (June 12, 2025, 1:42 p.m.)
Issued 40 years ago (Aug. 1, 1985)
Published 40 years ago (Aug. 1, 1985)
Published Print 40 years ago (Aug. 1, 1985)
Funders 0

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@article{Begg_1985, title={Cell shape and division in Escherichia coli: experiments with shape and division mutants}, volume={163}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.163.2.615-622.1985}, DOI={10.1128/jb.163.2.615-622.1985}, number={2}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Begg, K J and Donachie, W D}, year={1985}, month=aug, pages={615–622} }