Deg phenotype of Escherichia coli lon mutants
10.1128/jb.133.2.844-851.1978
Crossref journal-article
American Society for Microbiology
Journal of Bacteriology (235)
Abstract

Deg. one of the Escherichia coli systems for degrading abnormal polypeptides (e.g., nonsense fragments), is also involved in the degradation of some classes of missense proteins. Both missense proteins of beta-galactosidase and temperature-sensitive phage products appear to be degraded by the Deg system. Mutations in the Deg system are indistinguishable from mutations classically called lon or capR; all map near proC, all are mucoid, defective in protein degradation, sensitive to radiomimetic agents, and defective in P1 lysogenization. All are able to propagate temperature-sensitive phage better than lon+ parental strains. Mutations that suppress the radiation sensitivity of these strains (sul) also suppress the P1 lysogenization defect, but do not affect mucoidy or the degradation defect.

Bibliography

Gottesman, S., & Zipser, D. (1978). Deg phenotype of Escherichia coli lon mutants. Journal of Bacteriology, 133(2), 844–851.

Authors 2
  1. S Gottesman (first)
  2. D Zipser (additional)
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Dates
Type When
Created 5 years, 7 months ago (Jan. 3, 2020, 11:21 a.m.)
Deposited 4 years, 1 month ago (July 29, 2021, 1:29 p.m.)
Indexed 1 year, 7 months ago (Jan. 13, 2024, 4:29 a.m.)
Issued 47 years, 6 months ago (Feb. 1, 1978)
Published 47 years, 6 months ago (Feb. 1, 1978)
Published Print 47 years, 6 months ago (Feb. 1, 1978)
Funders 0

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@article{Gottesman_1978, title={Deg phenotype of Escherichia coli lon mutants}, volume={133}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.133.2.844-851.1978}, DOI={10.1128/jb.133.2.844-851.1978}, number={2}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Gottesman, S and Zipser, D}, year={1978}, month=feb, pages={844–851} }