Missense mutations in the lacZ gene that result in degradation of beta-galactosidase structural protein
10.1128/jb.127.3.1538-1542.1976
Crossref journal-article
American Society for Microbiology
Journal of Bacteriology (235)
Abstract

Thirty-two missenese mutations were found among more than 200 independently induced mutations in the lacZ gene of Escherichia coli. Twenty of these missense mutations were induced by nitrosguandine, and 12 were induced by aminopurine. The lacZ structural protein was endogenously degradable in seven of the mutant strains; the mutations in these strains were found to lie at only three sites in the lacZ gene. Five of the seven independent mutations were at a single site, and some heterogeneity in the degradation of the lacZ protein was observed within these mutant strains.

Bibliography

Zipser, D., & Bhavsar, P. (1976). Missense mutations in the lacZ gene that result in degradation of beta-galactosidase structural protein. Journal of Bacteriology, 127(3), 1538–1542.

Authors 2
  1. D Zipser (first)
  2. P Bhavsar (additional)
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Dates
Type When
Created 5 years, 8 months ago (Jan. 3, 2020, 11:05 a.m.)
Deposited 2 years, 10 months ago (Oct. 9, 2022, 5:48 p.m.)
Indexed 1 year, 9 months ago (Nov. 23, 2023, 7:42 a.m.)
Issued 49 years ago (Sept. 1, 1976)
Published 49 years ago (Sept. 1, 1976)
Published Print 49 years ago (Sept. 1, 1976)
Funders 0

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@article{Zipser_1976, title={Missense mutations in the lacZ gene that result in degradation of beta-galactosidase structural protein}, volume={127}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.127.3.1538-1542.1976}, DOI={10.1128/jb.127.3.1538-1542.1976}, number={3}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Zipser, D and Bhavsar, P}, year={1976}, month=sep, pages={1538–1542} }