DOI: 10.1128/jb.126.2.758-770.1976. cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis

cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis

10.1128/jb.126.2.758-770.1976

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

Motile but generally nonchemotatic (che) mutants of Escherichia coli were isolated by a simple screening method. A total of 172 independent mutants were examined, and four genes were defined on the basis of mapping and complemenvestigated by determining their null phenotypes with nonsense or bacteriophage Mu-induced mutations. The cheA and cheB products were essential in producing changes of swimming direction and flagellar rotation. The checC product appeared to be an essential component of the flagellum; however, specific mutational alterations of this component allowed flagellar assembly but prevented directional changes in swimming. Since some cheB mutants changed directions incessantly, this gene product may also serve to control the direction of flagellar rotation in response to chemoreceptor signals. Thus most or all of the common elements in the signalling process were involved in the generation and regulation of changes in the direction of flagellar rotation.

Bibliography

Parkinson, J. S. (1976). cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis. Journal of Bacteriology, 126(2), 758â770.

Authors 1

J S Parkinson (first)

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Dates

Type	When
Created	5 years, 7 months ago (Jan. 3, 2020, 11:02 a.m.)
Deposited	4 years ago (July 29, 2021, 1:20 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 6, 2025, 8:20 a.m.)
Issued	49 years, 3 months ago (May 1, 1976)
Published	49 years, 3 months ago (May 1, 1976)
Published Print	49 years, 3 months ago (May 1, 1976)

Funders 0

None

BibTeX

@article{Parkinson_1976, title={cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis}, volume={126}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.126.2.758-770.1976}, DOI={10.1128/jb.126.2.758-770.1976}, number={2}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Parkinson, J S}, year={1976}, month=may, pages={758–770} }

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