Abstract
Treponema pallidum was observed to incorporate glucose carbons into lipids, ribonucleic acid, deoxyribonucleic acid, and protein. Only the glycerol portions of phosphatidylcholine and phosphatidylglycerol contained glucose-derived carbons. Incorporation of exogenous choline into phosphatidylcholine was detected. Glucose was incorporated into only the pentoses of nucleic acids. About 50% of the glucose incorporated into protein was present in only one amino acid, aspartate. Evidence suggests that aspartate synthesis could follow the conversion of phosphoenolpyruvate to oxalacetic acid by a guanosine 5'-diphosphate-dependent phosphoenolpyruvate carboxykinase.
Dates
Type | When |
---|---|
Created | 5 years, 7 months ago (Jan. 2, 2020, 9:40 p.m.) |
Deposited | 3 years, 5 months ago (March 4, 2022, 4:43 p.m.) |
Indexed | 1 year, 7 months ago (Jan. 12, 2024, 11:03 p.m.) |
Issued | 44 years, 5 months ago (March 1, 1981) |
Published | 44 years, 5 months ago (March 1, 1981) |
Published Print | 44 years, 5 months ago (March 1, 1981) |
@article{Barbieri_1981, title={Distribution of glucose incorporated into macromolecular material by treponema pallidum}, volume={31}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.31.3.1071-1077.1981}, DOI={10.1128/iai.31.3.1071-1077.1981}, number={3}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Barbieri, J T and Austin, F E and Cox, C D}, year={1981}, month=mar, pages={1071–1077} }