DOI: 10.1128/mcb.8.4.1853. Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.

10.1128/mcb.8.4.1853

Crossref journal-article

Informa UK Limited

Molecular and Cellular Biology (301)

Abstract

We isolated and sequenced a cDNA clone of the human gene encoded by the 5' half of the ret transforming gene. The nucleotide sequence indicates that it encodes a protein with "finger" structures which represent putative metal- and nucleic acid-binding domains. Transcription of this gene was detected at high levels in a variety of human and rodent tumor cell lines, mouse testis, and embryos. In addition, a unique transcript was observed in testis RNA. When the expression of the unique transcript was examined at different stages of spermatogenesis, a striking increase in mRNA levels accompanied progression from meiotic prophase pachytene spermatocytes to postmeiotic round spermatids. This finger-containing gene may thus function in male germ cell development.

Bibliography

Takahashi, M., Inaguma, Y., Hiai, H., & Hirose, F. (1988). Developmentally regulated expression of a human âfingerâ-containing gene encoded by the 5â half of the ret transforming gene. Molecular and Cellular Biology, 8(4), 1853â1856.

Authors 4

M Takahashi (first)
Y Inaguma (additional)
H Hiai (additional)
F Hirose (additional)

References 0 Referenced 128

None

Dates

Type	When
Created	9 years, 10 months ago (Sept. 30, 2015, 3:46 p.m.)
Deposited	2 years, 8 months ago (Dec. 15, 2022, 8:54 a.m.)
Indexed	1 year, 7 months ago (Jan. 12, 2024, 8:07 p.m.)
Issued	37 years, 4 months ago (April 1, 1988)
Published	37 years, 4 months ago (April 1, 1988)
Published Online	37 years, 4 months ago (April 1, 1988)
Published Print	37 years, 4 months ago (April 1, 1988)

Funders 0

None

BibTeX

@article{Takahashi_1988, title={Developmentally regulated expression of a human “finger”-containing gene encoded by the 5’ half of the ret transforming gene.}, volume={8}, ISSN={1098-5549}, url={http://dx.doi.org/10.1128/mcb.8.4.1853}, DOI={10.1128/mcb.8.4.1853}, number={4}, journal={Molecular and Cellular Biology}, publisher={Informa UK Limited}, author={Takahashi, M and Inaguma, Y and Hiai, H and Hirose, F}, year={1988}, month=apr, pages={1853–1856} }

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