DOI: 10.1128/mcb.7.2.639. Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

10.1128/mcb.7.2.639

Crossref journal-article

Informa UK Limited

Molecular and Cellular Biology (301)

Abstract

Mouse 3T3 cells were transformed with an antisense c-fos gene fused to a mouse mammary tumor virus promoter. In transformants that integrated a large number of antisense c-fos sequences, the usual large increase in c-fos mRNA and protein following stimulation of quiescent cells by platelet-derived growth factor was blocked in the presence of dexamethasone. These cells subsequently also failed to show the stimulation of DNA synthesis normally induced by platelet-derived growth factor. Appropriate expression of c-fos appears to be a prerequisite for reentry of quiescent cells into the cell cycle.

Bibliography

Nishikura, K., & Murray, J. M. (1987). Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells. Molecular and Cellular Biology, 7(2), 639â649.

Authors 2

K Nishikura (first)
J M Murray (additional)

References 0 Referenced 207

None

Dates

Type	When
Created	9 years, 10 months ago (Sept. 30, 2015, 3:40 p.m.)
Deposited	2 years, 8 months ago (Dec. 15, 2022, 8:53 a.m.)
Indexed	11 months, 2 weeks ago (Sept. 3, 2024, 4:58 a.m.)
Issued	38 years, 6 months ago (Feb. 1, 1987)
Published	38 years, 6 months ago (Feb. 1, 1987)
Published Online	38 years, 6 months ago (Feb. 1, 1987)
Published Print	38 years, 6 months ago (Feb. 1, 1987)

Funders 0

None

BibTeX

@article{Nishikura_1987, title={Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.}, volume={7}, ISSN={1098-5549}, url={http://dx.doi.org/10.1128/mcb.7.2.639}, DOI={10.1128/mcb.7.2.639}, number={2}, journal={Molecular and Cellular Biology}, publisher={Informa UK Limited}, author={Nishikura, K and Murray, J M}, year={1987}, month=feb, pages={639–649} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        3
      ]
    ],
    "date-time": "2024-09-03T08:58:18Z",
    "timestamp": 1725353898091
  },
  "reference-count": 0,
  "publisher": "Informa UK Limited",
  "issue": "2",
  "content-domain": {
    "domain": [
      "asm.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1987,
        2
      ]
    ]
  },
  "abstract": "<jats:p>Mouse 3T3 cells were transformed with an antisense c-fos gene fused to a mouse mammary tumor virus promoter. In transformants that integrated a large number of antisense c-fos sequences, the usual large increase in c-fos mRNA and protein following stimulation of quiescent cells by platelet-derived growth factor was blocked in the presence of dexamethasone. These cells subsequently also failed to show the stimulation of DNA synthesis normally induced by platelet-derived growth factor. Appropriate expression of c-fos appears to be a prerequisite for reentry of quiescent cells into the cell cycle.</jats:p>",
  "DOI": "10.1128/mcb.7.2.639",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2015,
        9,
        30
      ]
    ],
    "date-time": "2015-09-30T19:40:30Z",
    "timestamp": 1443642030000
  },
  "page": "639-649",
  "update-policy": "http://dx.doi.org/10.1128/asmj-crossmark-policy-page",
  "source": "Crossref",
  "is-referenced-by-count": 207,
  "title": "Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.",
  "prefix": "10.1080",
  "volume": "7",
  "author": [
    {
      "given": "K",
      "family": "Nishikura",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "J M",
      "family": "Murray",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "301",
  "published-online": {
    "date-parts": [
      [
        1987,
        2,
        1
      ]
    ]
  },
  "container-title": "Molecular and Cellular Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1128/MCB.7.2.639",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        12,
        15
      ]
    ],
    "date-time": "2022-12-15T13:53:11Z",
    "timestamp": 1671112391000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "http://mcb.asm.org/lookup/doi/10.1128/MCB.7.2.639"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1987,
        2
      ]
    ]
  },
  "references-count": 0,
  "journal-issue": {
    "issue": "2",
    "published-online": {
      "date-parts": [
        [
          1987,
          2,
          1
        ]
      ]
    },
    "published-print": {
      "date-parts": [
        [
          1987,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1128/MCB.7.2.639"
  ],
  "URL": "http://dx.doi.org/10.1128/MCB.7.2.639",
  "relation": {},
  "ISSN": [
    "0270-7306",
    "1098-5549"
  ],
  "subject": [],
  "container-title-short": "Mol. Cell. Biol.",
  "published": {
    "date-parts": [
      [
        1987,
        2
      ]
    ]
  }
}