DOI: 10.1128/mcb.6.2.494. A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae.

A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae.

10.1128/mcb.6.2.494

Crossref journal-article

Informa UK Limited

Molecular and Cellular Biology (301)

Abstract

The SIR genes of Saccharomyces cerevisiae are responsible for the position-dependent regulation of the a and alpha mating-type genes. Previous work by others has shown that the products of the SIR genes prevent the accumulation of stable transcripts of the a and alpha genes at HML and HMR. Results of this study establish that this regulation is a region-specific effect rather than a gene-specific effect since expression of a tRNA gene placed at HMR is repressed by the products of the SIR genes.

Bibliography

Schnell, R., & Rine, J. (1986). A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae. Molecular and Cellular Biology, 6(2), 494â501.

Authors 2

R Schnell (first)
J Rine (additional)

References 0 Referenced 30

None

Dates

Type	When
Created	9 years, 10 months ago (Sept. 30, 2015, 3:36 p.m.)
Deposited	2 years, 8 months ago (Dec. 15, 2022, 8:51 a.m.)
Indexed	1 month, 3 weeks ago (July 2, 2025, 2:47 p.m.)
Issued	39 years, 6 months ago (Feb. 1, 1986)
Published	39 years, 6 months ago (Feb. 1, 1986)
Published Online	39 years, 6 months ago (Feb. 1, 1986)
Published Print	39 years, 6 months ago (Feb. 1, 1986)

Funders 0

None

BibTeX

@article{Schnell_1986, title={A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae.}, volume={6}, ISSN={1098-5549}, url={http://dx.doi.org/10.1128/mcb.6.2.494}, DOI={10.1128/mcb.6.2.494}, number={2}, journal={Molecular and Cellular Biology}, publisher={Informa UK Limited}, author={Schnell, R and Rine, J}, year={1986}, month=feb, pages={494–501} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        2
      ]
    ],
    "date-time": "2025-07-02T18:47:32Z",
    "timestamp": 1751482052210
  },
  "reference-count": 0,
  "publisher": "Informa UK Limited",
  "issue": "2",
  "content-domain": {
    "domain": [
      "asm.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1986,
        2
      ]
    ]
  },
  "abstract": "<jats:p>The SIR genes of Saccharomyces cerevisiae are responsible for the position-dependent regulation of the a and alpha mating-type genes. Previous work by others has shown that the products of the SIR genes prevent the accumulation of stable transcripts of the a and alpha genes at HML and HMR. Results of this study establish that this regulation is a region-specific effect rather than a gene-specific effect since expression of a tRNA gene placed at HMR is repressed by the products of the SIR genes.</jats:p>",
  "DOI": "10.1128/mcb.6.2.494",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2015,
        9,
        30
      ]
    ],
    "date-time": "2015-09-30T19:36:00Z",
    "timestamp": 1443641760000
  },
  "page": "494-501",
  "update-policy": "http://dx.doi.org/10.1128/asmj-crossmark-policy-page",
  "source": "Crossref",
  "is-referenced-by-count": 30,
  "title": "A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae.",
  "prefix": "10.1080",
  "volume": "6",
  "author": [
    {
      "given": "R",
      "family": "Schnell",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "J",
      "family": "Rine",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "301",
  "published-online": {
    "date-parts": [
      [
        1986,
        2,
        1
      ]
    ]
  },
  "container-title": "Molecular and Cellular Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1128/MCB.6.2.494",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2022,
        12,
        15
      ]
    ],
    "date-time": "2022-12-15T13:51:19Z",
    "timestamp": 1671112279000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "http://mcb.asm.org/lookup/doi/10.1128/MCB.6.2.494"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1986,
        2
      ]
    ]
  },
  "references-count": 0,
  "journal-issue": {
    "issue": "2",
    "published-online": {
      "date-parts": [
        [
          1986,
          2,
          1
        ]
      ]
    },
    "published-print": {
      "date-parts": [
        [
          1986,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1128/MCB.6.2.494"
  ],
  "URL": "http://dx.doi.org/10.1128/MCB.6.2.494",
  "relation": {},
  "ISSN": [
    "0270-7306",
    "1098-5549"
  ],
  "subject": [],
  "container-title-short": "Mol. Cell. Biol.",
  "published": {
    "date-parts": [
      [
        1986,
        2
      ]
    ]
  }
}