DOI: 10.1128/mcb.20.19.7109-7120.2000. New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

10.1128/mcb.20.19.7109-7120.2000

Crossref journal-article

Informa UK Limited

Molecular and Cellular Biology (301)

Bibliography

Gu, H., Maeda, H., Moon, J. J., Lord, J. D., Yoakim, M., Nelson, B. H., & Neel, B. G. (2000). New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway. Molecular and Cellular Biology, 20(19), 7109â7120.

Authors 7

Haihua Gu (first)
Hiroyuki Maeda (additional)
James J. Moon (additional)
James D. Lord (additional)
Monique Yoakim (additional)
Brad H. Nelson (additional)
Benjamin G. Neel (additional)

References 63 Referenced 216

10.1038/35003228
10.1002/j.1460-2075.1992.tb05426.x
10.1016/S0969-2126(98)00027-6
10.1111/j.1432-1033.1995.084_c.x / Eur. J. Biochem. by Baxter R. M. (1995)
10.1074/jbc.272.22.14470
10.1016/S0898-6568(99)00088-1
10.1016/S0968-0004(96)10033-5
10.1016/S1074-7613(00)80388-X
10.1016/S0021-9258(18)98375-4
10.1016/S0021-9258(17)45429-9
10.1016/S0962-8924(99)01709-2
10.1074/jbc.274.15.10633
10.1074/jbc.272.46.29281 / J. Biol. Chem. by Craddock B. L. (1997)
10.1038/sj.onc.1202678
10.1016/S0959-437X(98)80061-0
10.1016/S0092-8674(00)81883-8
10.1074/jbc.273.29.18273 / J. Biol. Chem. by Gesbert F. (1998)
10.1002/j.1460-2075.1996.tb01008.x
10.1074/jbc.272.26.16421
10.1016/S1097-2765(00)80288-9
10.1038/sj.onc.1201980 / Oncogene by Hallberg B. (1998)
10.1038/379560a0
10.1073/pnas.94.23.12419
10.1074/jbc.274.4.2097
{'key': 'B25', 'first-page': 'S84', 'volume': '4', 'author': 'Ihle J. N.', 'year': '1998', 'journal-title': 'Cancer J. Sci. Am.'} / Cancer J. Sci. Am. by Ihle J. N. (1998)
10.1111/j.1749-6632.1998.tb11157.x
10.1074/jbc.273.46.30630
10.1128/MCB.18.2.742
10.1074/jbc.271.44.27931
10.1126/science.286.5438.309
10.1182/blood.V91.10.3927.3927_3927_3934
10.1016/S0092-8674(00)81022-3
10.1016/S1097-2765(00)80231-2
10.1101/gad.10.9.1084
10.4049/jimmunol.161.9.4627
10.1016/S1357-2725(97)00075-7
10.1128/MCB.19.3.1784
10.1074/jbc.274.44.31719
10.1128/MCB.18.8.4872
10.1073/pnas.95.26.15547
10.1016/S0955-0674(97)80063-4
10.1074/jbc.272.33.20811
10.1182/blood.V93.6.1809.406k35_1809_1816
10.1111/j.1749-6632.1999.tb08474.x
10.1182/blood.V90.12.4759 / Blood by Okuda K. (1997)
10.1074/jbc.271.21.12137
10.1074/jbc.272.35.22059
10.1073/pnas.93.11.5275
10.1128/MCB.20.4.1448-1459.2000
10.1074/jbc.274.51.36362
10.1042/bj3120159
10.1096/fasebj.9.9.7601337
10.1074/jbc.275.5.3568
10.1073/pnas.94.21.11345
10.1038/42648
10.1016/S0021-9258(17)37552-X
10.1016/S1074-7613(00)80103-X
10.1016/S0959-437X(98)80070-1
10.1074/jbc.270.21.12774
10.1074/jbc.274.35.24469
10.1038/sj.onc.1201678
10.1126/science.7652556
10.1074/jbc.274.28.19649

Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 5:58 a.m.)
Deposited	2 years, 5 months ago (March 28, 2023, 3:43 a.m.)
Indexed	1 month, 1 week ago (July 24, 2025, 7:30 a.m.)
Issued	24 years, 10 months ago (Oct. 15, 2000)
Published	24 years, 10 months ago (Oct. 15, 2000)
Published Online	2 years, 5 months ago (March 28, 2023)
Published Print	24 years, 10 months ago (Oct. 15, 2000)

Funders 0

None

BibTeX

@article{Gu_2000, title={New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway}, volume={20}, ISSN={1098-5549}, url={http://dx.doi.org/10.1128/mcb.20.19.7109-7120.2000}, DOI={10.1128/mcb.20.19.7109-7120.2000}, number={19}, journal={Molecular and Cellular Biology}, publisher={Informa UK Limited}, author={Gu, Haihua and Maeda, Hiroyuki and Moon, James J. and Lord, James D. and Yoakim, Monique and Nelson, Brad H. and Neel, Benjamin G.}, year={2000}, month=oct, pages={7109–7120} }

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