DOI: 10.1128/mcb.10.8.4080. Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP.

Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP.

10.1128/mcb.10.8.4080

Crossref journal-article

Informa UK Limited

Molecular and Cellular Biology (301)

Abstract

We dissected the promoter of the developmentally induced and cyclic AMP-repressed discoidin I gamma gene and identified a sequence element essential for developmental induction. Transfer of the element to an inactive heterologous promoter demonstrated that this sequence is sufficient to confer expression in axenically growing cells and to induce gene activity in development after growth on bacteria. A 16-base-pair sequence within this element was shown to be sufficient for induction in the discoidin promoter context and was used to reactivate different truncated promoter constructs. This led to the localization of an element necessary for down regulation of gene expression by extracellular cyclic AMP.

Bibliography

Vauti, F., Morandini, P., Blusch, J., Sachse, A., & Nellen, W. (1990). Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP. Molecular and Cellular Biology, 10(8), 4080â4088.

Authors 5

F Vauti (first)
P Morandini (additional)
J Blusch (additional)
A Sachse (additional)
W Nellen (additional)

References 0 Referenced 41

None

Dates

Type	When
Created	9 years, 11 months ago (Oct. 1, 2015, 5:58 p.m.)
Deposited	2 years, 8 months ago (Dec. 15, 2022, 9 a.m.)
Indexed	11 months, 3 weeks ago (Sept. 13, 2024, 12:43 p.m.)
Issued	35 years, 1 month ago (Aug. 1, 1990)
Published	35 years, 1 month ago (Aug. 1, 1990)
Published Online	35 years, 1 month ago (Aug. 1, 1990)
Published Print	35 years, 1 month ago (Aug. 1, 1990)

Funders 0

None

BibTeX

@article{Vauti_1990, title={Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP.}, volume={10}, ISSN={1098-5549}, url={http://dx.doi.org/10.1128/mcb.10.8.4080}, DOI={10.1128/mcb.10.8.4080}, number={8}, journal={Molecular and Cellular Biology}, publisher={Informa UK Limited}, author={Vauti, F and Morandini, P and Blusch, J and Sachse, A and Nellen, W}, year={1990}, month=aug, pages={4080–4088} }

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