DOI: 10.1128/jvi.76.7.3570-3574.2002. Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†

Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†

10.1128/jvi.76.7.3570-3574.2002

Crossref journal-article

American Society for Microbiology

Journal of Virology (235)

Abstract

ABSTRACTHepatitis B virus (HBV) replication is inhibited in a noncytopathic manner by alpha/beta interferon (IFN-α/β) and IFN-γ. We demonstrate here that inhibitors of cellular proteasome activity can block this antiviral effect. These results suggest that a critical component of the IFN-induced antiviral response may be the proteasome-dependent degradation of viral or cellular proteins that are required for HBV replication.

Bibliography

Robek, M. D., Wieland, S. F., & Chisari, F. V. (2002). Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activityâ . Journal of Virology, 76(7), 3570â3574.

Authors 3

Michael D. Robek (first)
Stefan F. Wieland (additional)
Francis V. Chisari (additional)

References 51 Referenced 74

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Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 5:59 a.m.)
Deposited	2 years, 4 months ago (April 23, 2023, 11:05 a.m.)
Indexed	4 months, 4 weeks ago (April 9, 2025, 2:02 a.m.)
Issued	23 years, 5 months ago (April 1, 2002)
Published	23 years, 5 months ago (April 1, 2002)
Published Print	23 years, 5 months ago (April 1, 2002)

Funders 0

None

BibTeX

@article{Robek_2002, title={Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†}, volume={76}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.76.7.3570-3574.2002}, DOI={10.1128/jvi.76.7.3570-3574.2002}, number={7}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Robek, Michael D. and Wieland, Stefan F. and Chisari, Francis V.}, year={2002}, month=apr, pages={3570–3574} }

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