DOI: 10.1128/jvi.64.11.5649-5651.1990. Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex

Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex

10.1128/jvi.64.11.5649-5651.1990

Crossref journal-article

American Society for Microbiology

Journal of Virology (235)

Abstract

Two cellular proteins, 61 and 37 kDa, are found in association with the simian virus 40 (SV40) small-t antigen. Fractionation in standard chromatography systems showed that these proteins were associated with one another in uninfected cells, suggesting that the small-t antigen may bind the complex as a whole and not each individual protein independently. In the presence of N-ethylmaleimide, the 37-kDA protein was selectively released from immune complexes, leaving the small-t antigen and 61-kDa protein in association. This result suggests that the small-t antigen may bind only the 61-kDa protein and that the 37-kDa protein may be associated with immune complexes by virtue of its association with the 61-kDa cellular protein.

Bibliography

Joshi, B., & Rundell, K. (1990). Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex. Journal of Virology, 64(11), 5649â5651.

Authors 2

B Joshi (first)
K Rundell (additional)

References 0 Referenced 19

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 6, 2020, 10:44 a.m.)
Deposited	3 years, 5 months ago (March 4, 2022, 6:47 p.m.)
Indexed	2 years, 4 months ago (March 31, 2023, 8:28 p.m.)
Issued	34 years, 9 months ago (Nov. 1, 1990)
Published	34 years, 9 months ago (Nov. 1, 1990)
Published Print	34 years, 9 months ago (Nov. 1, 1990)

Funders 0

None

BibTeX

@article{Joshi_1990, title={Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex}, volume={64}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.64.11.5649-5651.1990}, DOI={10.1128/jvi.64.11.5649-5651.1990}, number={11}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Joshi, B and Rundell, K}, year={1990}, month=nov, pages={5649–5651} }

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