Crossref journal-article
American Society for Microbiology
Journal of Virology (235)
Abstract

The monomer form of BK virus (BKV) tumor antigen (T Ag) was immunoprecipitated from extracts of BKV-transformed cells and had a molecular weight of approximately 113,000. This compared with 97,000 for the molecular weight of either BKV or simian virus 40 (SV40) T Ag from lytically infected cells. The SV40 and BKV T Ag's from productively infected cells were compared by examining their methionine-labeled tryptic peptides. Out of a total of 20 SV40-and 21 BKV-specific peptides, there were seven pairs of similar peptides on the basis of ion-exchange chromatography, These coeluting peptides contained approximately 25 to 30% of the total methionine radioactivity. Similar results were obtained when the tryptic peptides of SV40 T Ag from lytically infected cells were compared with those of BKV T Ag from virally transformed cells.

Bibliography

Simmons, D. T., Takemoto, K. K., & Martin, M. A. (1977). Relationship between the methionine tryptic peptides of simian virus 40 and BK virus tumor antigens. Journal of Virology, 24(1), 319–325.

Authors 3
  1. D T Simmons (first)
  2. K K Takemoto (additional)
  3. M A Martin (additional)
References 0 Referenced 23

None

Dates
Type When
Created 5 years, 7 months ago (Jan. 5, 2020, 7:44 p.m.)
Deposited 3 years, 6 months ago (March 5, 2022, 11:04 a.m.)
Indexed 1 year, 10 months ago (Oct. 19, 2023, 10:22 a.m.)
Issued 47 years, 11 months ago (Oct. 1, 1977)
Published 47 years, 11 months ago (Oct. 1, 1977)
Published Print 47 years, 11 months ago (Oct. 1, 1977)
Funders 0

None

@article{Simmons_1977, title={Relationship between the methionine tryptic peptides of simian virus 40 and BK virus tumor antigens}, volume={24}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.24.1.319-325.1977}, DOI={10.1128/jvi.24.1.319-325.1977}, number={1}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Simmons, D T and Takemoto, K K and Martin, M A}, year={1977}, month=oct, pages={319–325} }