DOI: 10.1128/jb.84.3.485-491.1962. MECHANISM OF GLUCOSE TRANSPORT ACROSS THE YEAST CELL MEMBRANE

MECHANISM OF GLUCOSE TRANSPORT ACROSS THE YEAST CELL MEMBRANE

10.1128/jb.84.3.485-491.1962

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

Cirillo, Vincent P. (Seton Hall College of Medicine and Dentistry, Jersey City, N.J.). Mechanism of glucose transport across the yeast cell membrane. J. Bacteriol. 84: 485–491. 1962.—The kinetics of d -glucose and l -sorbose transport was studied in Saccharomyces cerevisiae inhibited with iodoacetic acid under nitrogen to prevent glucose metabolism. d -Glucose was found to compete with l -sorbose for a common membrane transport system with an apparent affinity greater than 25 times that of sorbose. A comparison of the net rate of glucose and sorbose transport at 50 and 500 m m external concentration showed that glucose transport is greater than that of sorbose from the lower concentration, but sorbose transport is greater than glucose at the higher concentration. This reversal of transport rate of two sugars with markedly different affinities is predicted by the membrane carrier theory. A further prediction of carrier theory was confirmed by the demonstration that the rate of glucose transport into fructose-loaded cells is greater than into unloaded cells.

Bibliography

Cirillo, V. P. (1962). MECHANISM OF GLUCOSE TRANSPORT ACROSS THE YEAST CELL MEMBRANE. Journal of Bacteriology, 84(3), 485â491.

Authors 1

Vincent P. Cirillo (first)

References 23 Referenced 141

AVIGAD , A. 1960 . Accumulation of trehalose and sucrose in relation to the metabolism of a-glucosides in yeast of defined genotype . Biochim. et Biophys. Acta 40 : 124 - 134 . (10.1016/0006-3002(60)91322-6) / Biochim. et Biophys. Acta / Accumulation of trehalose and sucrose in relation to the metabolism of a-glucosides in yeast of defined genotype by AVIGAD A. (1960)
BURGER , M., L. HEJMOVA , A ND A . KLEINZELLER. 1959 . Transport of some monosaccharides into yeast cells . Biochem. J. 71 : 233 - 242 . (10.1042/bj0710233) / Biochem. J. / Transport of some monosaccharides into yeast cells by BURGER M., L. (1959)
CIRILLO V. P. 1961a. The transport of nonfermentable sugars across the yeast cell membrane p. 343-351. In A. Kleinzeller and A. Kotyk [ed.] Membrane transport and metabolism. Academic Press Inc. New York.
CIRILLO , V. P. 1961 b. The mechanism of sugar transport into the yeast cell. Trans. N.Y . Acad. Sci. Ser. II 23 : 725 - 734 . / Acad. Sci. Ser. II / The mechanism of sugar transport into the yeast cell. Trans. N.Y by CIRILLO V. P. (1961)
CIRILLO , V. P. 1961 c. Sugar transport in microorganisms . Ann. Rev. Microbiol. 15 : 197 - 218 . (10.1146/annurev.mi.15.100161.001213) / Ann. Rev. Microbiol. / Sugar transport in microorganisms by CIRILLO V. P. (1961)
CIRILLO V. P. 1962. Sugar transport in Tetrahymena. Bacteriol. Proc. p. 81.
DE LA FUENTE , G. , AND A. SOLS. 1962 . Transport of sugars in yeast. II. Mechanisms of utilization of disaccharides and related glycosides . Biochim. et Biophys. Acta 56 : 49 - 62 . / Biochim. et Biophys. Acta / Transport of sugars in yeast. II. Mechanisms of utilization of disaccharides and related glycosides by DE LA FUENTE G. (1962)
DISCHE , Z. , AND A. DEVI. 1960 . A new colorimetric method for the determination of ketohexoses in the presence of aldoses, ketoheptoses and ketopentoses . Biochim. et Biophys. Acta 39 : 140 - 144 . (10.1016/0006-3002(60)90129-3) / Biochim. et Biophys. Acta / A new colorimetric method for the determination of ketohexoses in the presence of aldoses, ketoheptoses and ketopentoses by DISCHE Z. (1960)
KEPES , A. 1960 . ]tudes cinetique sur la galactoside-permease d'Escherichia coli . Biochim. et Biophys. Acta 40 : 70 - 84 . (10.1016/0006-3002(60)91316-0) / Biochim. et Biophys. Acta / ]tudes cinetique sur la galactoside-permease d'Escherichia coli by KEPES A. (1960)
KOTYK A. 1961. The effect of oxygen on transport phenomena in a respiration-deficient mutant of baker's yeast p. 352-360. In A. Kleinzeller and A. Kotyk [ed.] Membrane transport metabolism. Academic Press Inc. New York.
I.E FEVRE , P. 1954 . The evidence for active transport of monosaccharides across the red cell membrane . Symposia Soc. Exptl. Biol. 8 : 118 - 135 . / Symposia Soc. Exptl. Biol. / The evidence for active transport of monosaccharides across the red cell membrane by FEVRE P. (1954)
NEISH A. C. 1952. Analytical methods for bacterial fermentations 2nd revision. Rept. no. 46-8-3 Natl. Council Canada.
PARK , C. R. , R. L. POST , C. F. KALMAN , J. H. WRIGHT , JR. , L. H. JOHNSON , A ND H . E. MORGAN. 1956 . The transport of glucose and other sugars across cell membrane transports involving insulin . Ciba Colloquia Endocrinol. 9 : 240 - 260 . / Ciba Colloquia Endocrinol. / The transport of glucose and other sugars across cell membrane transports involving insulin by PARK C. R. (1956)
PARK , C. R. , D. REINWEIN , M. J. HUNDERSON , E. CADENAS , A ND H . E. MORGAN. 1959 . The action of insulin on the transport of glucose through the cell membrane . Am. J. Med. 26 : 674 - 684 . (10.1016/0002-9343(59)90227-X) / Am. J. Med. / The action of insulin on the transport of glucose through the cell membrane by PARK C. R. (1959)
ROBERTSON , J. J. , AND H. 0. HALVORSON. 1957 . The components of maltozymase in yeast and their behavior during deadaptation . J. Bacteriol. 73 : 186 - 198 . (10.1128/JB.73.2.186-198.1957) / J. Bacteriol. / The components of maltozymase in yeast and their behavior during deadaptation by ROBERTSON J. J. (1957)
ROSENBERG , T. , AND W. WILBRANDT. 1955 . The kinetics of membrane transport involving chemical reactions . Exptl. Cell Research 9 : 49 - 67 . (10.1016/0014-4827(55)90160-9) / Exptl. Cell Research / The kinetics of membrane transport involving chemical reactions by ROSENBERG T. (1955)
ROSENBERG , T. , AND W. WILBRANDT. 1958 . Uphill transport induced by counterflow . J. Gen. Physiol. 41 : 289 - 296 . (10.1085/jgp.41.2.289) / J. Gen. Physiol. / Uphill transport induced by counterflow by ROSENBERG T. (1958)
ROTMAN B. AND R. GU ZMAN. 1961. Transport of galactose from the inside to the outside of Escherichia coli p. 806-810. Pathologic-Biologie Xe Congres International de Biologie Cellulaire.
SCHARFF , T. ( X. 1961 . Evidence for hexose transport in acetone-dried yeast . Arch. Biochem. Biophys. 95 : 329 - 335 . (10.1016/0003-9861(61)90155-2) / Arch. Biochem. Biophys. / Evidence for hexose transport in acetone-dried yeast by SCHARFF T. (1961)
UMBREIT W. W. R. H. BURRIS AND J. F. STAUFFER. 1957. Manometric techniques and tissue metabolism. Burgess Publishing Co. Minneapolis.
WIDDAS , W. F. 1954 . Facilitated transfer of hexoses across the human erythrocyte membrane . J. Physiol. 125 : 163 - 180 . (10.1113/jphysiol.1954.sp005148) / J. Physiol. / Facilitated transfer of hexoses across the human erythrocyte membrane by WIDDAS W. F. (1954)
WILBRANDT , W. , AND T. ROSENBERG. 1961 . The concept of carrier transport and its corollaries in pharmacology . Pharmacol. Revs. 13 : 109 - 183 . / Pharmacol. Revs. / The concept of carrier transport and its corollaries in pharmacology by WILBRANDT W. (1961)
WISE , C. S. , R. J. D) IMLER , H. A. DAVIS , A ND C . E. RIST. 1955 . Determination of easily hydrolyzable fructose units in dextran preparations . Anal. Chem. 27 : 33 - 36 . (10.1021/ac60097a011) / Anal. Chem. / Determination of easily hydrolyzable fructose units in dextran preparations by WISE C. S. (1955)

Dates

Type	When
Created	5 years, 7 months ago (Jan. 3, 2020, 4:23 p.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:10 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 12, 2025, 6:14 p.m.)
Issued	63 years ago (Sept. 1, 1962)
Published	63 years ago (Sept. 1, 1962)
Published Print	63 years ago (Sept. 1, 1962)

Funders 0

None

BibTeX

@article{Cirillo_1962, title={MECHANISM OF GLUCOSE TRANSPORT ACROSS THE YEAST CELL MEMBRANE}, volume={84}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.84.3.485-491.1962}, DOI={10.1128/jb.84.3.485-491.1962}, number={3}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Cirillo, Vincent P.}, year={1962}, month=sep, pages={485–491} }

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