DOI: 10.1128/jb.184.8.2148-2154.2002. <i>Bacillus subtilis</i> 168 Contains Two Differentially Regulated Genes Encoding <scp>l</scp> -Asparaginase

Bacillus subtilis 168 Contains Two Differentially Regulated Genes Encoding l -Asparaginase

10.1128/jb.184.8.2148-2154.2002

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

ABSTRACT Expression of the two Bacillus subtilis genes encoding l -asparaginase is controlled by independent regulatory factors. The ansZ gene (formerly yccC ) was shown by mutational analysis to encode a functional l -asparaginase, the expression of which is activated during nitrogen-limited growth by the TnrA transcription factor. Gel mobility shift and DNase I footprinting experiments indicate that TnrA regulates ansZ expression by binding to a DNA site located upstream of the ansZ promoter. The expression of the ansA gene, which encodes the second l -asparaginase, was found to be induced by asparagine. The ansA repressor, AnsR, was shown to negatively regulate its own expression.

Bibliography

Fisher, S. H., & Wray, L. V. (2002). Bacillus subtilis 168 Contains Two Differentially Regulated Genes Encoding l -Asparaginase. Journal of Bacteriology, 184(8), 2148â2154.

Authors 2

Susan H. Fisher (first)
Lewis V. Wray (additional)

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Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 5:59 a.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 2:07 p.m.)
Indexed	1 year, 1 month ago (July 29, 2024, 8:32 a.m.)
Issued	23 years, 4 months ago (April 15, 2002)
Published	23 years, 4 months ago (April 15, 2002)
Published Print	23 years, 4 months ago (April 15, 2002)

Funders 0

None

BibTeX

@article{Fisher_2002, title={Bacillus subtilis 168 Contains Two Differentially Regulated Genes Encoding <scp>l</scp> -Asparaginase}, volume={184}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.184.8.2148-2154.2002}, DOI={10.1128/jb.184.8.2148-2154.2002}, number={8}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Fisher, Susan H. and Wray, Lewis V.}, year={2002}, month=apr, pages={2148–2154} }

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