DOI: 10.1128/jb.181.21.6828-6831.1999. Mutations in the Regulatory Gene hrpG of Xanthomonas campestris pv. vesicatoria Result in Constitutive Expression of All hrp Genes

Mutations in the Regulatory Gene hrpG of Xanthomonas campestris pv. vesicatoria Result in Constitutive Expression of All hrp Genes

10.1128/jb.181.21.6828-6831.1999

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

ABSTRACT hrpG is a key regulatory gene for transcriptional activation of pathogenicity genes ( hrp ) of Xanthomonas campestris pv. vesicatoria. We identified three mutations in hrpG which render hrp gene expression constitutive in normally suppressing medium. The mutations in hrpG result in novel amino acid substitutions compared to mutations in related proteins, such as OmpR. In addition, mutated hrpG enhances the timing and intensity of plant reactions in infection assays.

Bibliography

Wengelnik, K., Rossier, O., & Bonas, U. (1999). Mutations in the Regulatory Gene hrpG of Xanthomonas campestris pv. vesicatoria Result in Constitutive Expression of All hrp Genes. Journal of Bacteriology, 181(21), 6828â6831.

Authors 3

Kai Wengelnik (first)
Ombeline Rossier (additional)
Ulla Bonas (additional)

References 22 Referenced 137

Bogdanove A. Beer S. V. Bonas U. Boucher C. A. Collmer A. Coplin D. L. Cornelis G. R. Huang H.-C. Hutcheson S. W. Panopoulos N. J. Van Gijsegem F. Unified nomenclature for broadly conserved hrp genes of phytopathogenic bacteria.Mol. Microbiol.201996681683 (10.1046/j.1365-2958.1996.5731077.x) / Mol. Microbiol. / Unified nomenclature for broadly conserved hrp genes of phytopathogenic bacteria by Bogdanove A. (1996)
Bonas U. Unpublished data.
Bonas U. Schulte R. Fenselau S. Minsavage G. V. Staskawicz B. J. Isolation of a gene cluster from Xanthomonas campestris pv. vesicatoria that determines pathogenicity and the hypersensitive response on pepper and tomato.Mol. Plant-Microbe Interact.419918188 (10.1094/MPMI-4-081) / Mol. Plant-Microbe Interact. / Isolation of a gene cluster from Xanthomonas campestris pv. vesicatoria that determines pathogenicity and the hypersensitive response on pepper and tomato by Bonas U. (1991)
10.1128/jb.164.2.578-584.1985
Fenselau S. Balbo I. Bonas U. Determinants of pathogenicity in Xanthomonas campestris pv. vesicatoria are related to proteins involved in secretion in bacterial pathogens of animals.Mol. Plant-Microbe Interact.51992390396 (10.1094/MPMI-5-390) / Mol. Plant-Microbe Interact. / Determinants of pathogenicity in Xanthomonas campestris pv. vesicatoria are related to proteins involved in secretion in bacterial pathogens of animals by Fenselau S. (1992)
Fenselau S. Bonas U. Sequence and expression analysis of the hrpB pathogenicity operon of Xanthomonas campestris pv. vesicatoria which encodes eight proteins with similarity to components of the Hrp, Ysc, Spa, and Fli secretion systems.Mol. Plant-Microbe Interact.81995845854 (10.1094/MPMI-8-0845) / Mol. Plant-Microbe Interact. / Sequence and expression analysis of the hrpB pathogenicity operon of Xanthomonas campestris pv. vesicatoria which encodes eight proteins with similarity to components of the Hrp, Ysc, Spa, and Fli secretion systems by Fenselau S. (1995)
Huguet E. Hahn K. Wengelnik K. Bonas U. hpaA mutants of Xanthomonas campestris pv. vesicatoria are affected in pathogenicity but retain the ability to induce host-specific hypersensitive reaction.Mol. Microbiol.29199813791390 (10.1046/j.1365-2958.1998.01019.x) / Mol. Microbiol. / hpaA mutants of Xanthomonas campestris pv. vesicatoria are affected in pathogenicity but retain the ability to induce host-specific hypersensitive reaction by Huguet E. (1998)
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10.1006/jmbi.1996.0298
Martinez-Hackert E. Stock A. M. Structural relationships in the OmpR family of winged-helix transcription factors.J. Mol. Biol.2391997301312 (10.1006/jmbi.1997.1065) / J. Mol. Biol. / Structural relationships in the OmpR family of winged-helix transcription factors by Martinez-Hackert E. (1997)
Minsavage G. V. Dahlbeck D. Whalen M. C. Kearney B. Bonas U. Staskawicz B. J. Stall R. E. Gene-for-gene relationships specifying disease resistance in Xanthomonas campestris pv. vesicatoria-pepper interactions.Mol. Plant-Microbe Interact.319904147 (10.1094/MPMI-3-041) / Mol. Plant-Microbe Interact. / Gene-for-gene relationships specifying disease resistance in Xanthomonas campestris pv. vesicatoria-pepper interactions by Minsavage G. V. (1990)
10.1128/jb.174.12.4169-4174.1992
Pratt L. A. Silhavy T. J. OmpR mutants specifically defective for transcriptional activation.J. Mol. Biol.2431994579594 (10.1016/0022-2836(94)90033-7) / J. Mol. Biol. / OmpR mutants specifically defective for transcriptional activation by Pratt L. A. (1994)
Prentki P. Krisch H. M. In vitro insertion mutagenesis with a selectable DNA fragment.Gene291984303313 (10.1016/0378-1119(84)90059-3) / Gene / In vitro insertion mutagenesis with a selectable DNA fragment by Prentki P. (1984)
Russo F. D. Slauch J. M. Silhavy T. J. Mutations that affect separate functions of OmpR the phosphorylated regulator of porin transcription in Escherichia coli.J. Mol. Biol.2311993261273 (10.1006/jmbi.1993.1281) / J. Mol. Biol. / Mutations that affect separate functions of OmpR the phosphorylated regulator of porin transcription in Escherichia coli by Russo F. D. (1993)
10.1128/jb.174.3.815-823.1992
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Wurtzel E. T. Chou M. Y. Inouye M. Osmoregulation of gene expression. I. DNA sequence of the ompR gene of the ompB operon of Escherichia coli and characterization of its gene product.J. Biol. Chem.25719821368513691 (10.1016/S0021-9258(18)33501-4) / J. Biol. Chem. / Osmoregulation of gene expression. I. DNA sequence of the ompR gene of the ompB operon of Escherichia coli and characterization of its gene product by Wurtzel E. T. (1982)

Dates

Type	When
Created	5 years, 8 months ago (Dec. 31, 2019, 11:42 a.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:50 p.m.)
Indexed	1 week, 1 day ago (Aug. 29, 2025, 6:12 a.m.)
Issued	25 years, 10 months ago (Nov. 1, 1999)
Published	25 years, 10 months ago (Nov. 1, 1999)
Published Print	25 years, 10 months ago (Nov. 1, 1999)

Funders 0

None

BibTeX

@article{Wengelnik_1999, title={Mutations in the Regulatory Gene hrpG of Xanthomonas campestris pv. vesicatoria Result in Constitutive Expression of All hrp Genes}, volume={181}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.181.21.6828-6831.1999}, DOI={10.1128/jb.181.21.6828-6831.1999}, number={21}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Wengelnik, Kai and Rossier, Ombeline and Bonas, Ulla}, year={1999}, month=nov, pages={6828–6831} }

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      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}