DOI: 10.1128/jb.181.2.552-555.1999. <i>Helicobacter pylori</i> : a Eubacterium Lacking the Stringent Response

Helicobacter pylori : a Eubacterium Lacking the Stringent Response

10.1128/jb.181.2.552-555.1999

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

ABSTRACT Accumulation of 16S rRNA and production of guanosine polyphosphates (pppGpp and ppGpp) were studied during amino acid starvation in three wild-type strains of Helicobacter pylori . All strains exhibit a relaxed phenotype with respect to accumulation of 16S rRNA. This constitutes the first example of a wild-type eubacterium showing a relaxed phenotype. The guanosine polyphosphate levels do not rise as a result of amino acid starvation, as expected for relaxed organisms. However, in both growing and starved cells, basal levels of the two polyphosphates appeared to be present, demonstrating that the enzymatic machinery for guanosine polyphosphate production is present in this organism. These findings are discussed within the framework of the hypothesis that stringent control is a physiological control mechanism more important for the fitness of prokaryotes growing in the general environment than for those that inhabit protected niches.

Bibliography

Scoarughi, G. L., Cimmino, C., & Donini, P. (1999). Helicobacter pylori â¯: a Eubacterium Lacking the Stringent Response. Journal of Bacteriology, 181(2), 552â555.

Authors 3

Gian Luca Scoarughi (first)
Carmen Cimmino (additional)
Pierluigi Donini (additional)

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Dates

Type	When
Created	5 years, 8 months ago (Dec. 31, 2019, 11:41 a.m.)
Deposited	4 years, 1 month ago (July 29, 2021, 1:50 p.m.)
Indexed	1 year, 7 months ago (Jan. 26, 2024, 6 p.m.)
Issued	26 years, 7 months ago (Jan. 15, 1999)
Published	26 years, 7 months ago (Jan. 15, 1999)
Published Print	26 years, 7 months ago (Jan. 15, 1999)

Funders 0

None

BibTeX

@article{Scoarughi_1999, title={Helicobacter pylori  : a Eubacterium Lacking the Stringent Response}, volume={181}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.181.2.552-555.1999}, DOI={10.1128/jb.181.2.552-555.1999}, number={2}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Scoarughi, Gian Luca and Cimmino, Carmen and Donini, Pierluigi}, year={1999}, month=jan, pages={552–555} }

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