DOI: 10.1128/jb.108.1.410-414.1971. Histidine Regulation in <i>Salmonella typhimurium</i> VIII. Mutations of the <i>hisT</i> Gene

Histidine Regulation in Salmonella typhimurium VIII. Mutations of the hisT Gene

10.1128/jb.108.1.410-414.1971

Crossref journal-article

American Society for Microbiology

Journal of Bacteriology (235)

Abstract

The hisT gene, one of six genes in which mutation causes derepression of the histidine operon in Salmonella typhimurium , is shown to code for a protein that is not essential for the growth of the bacteria. This is indicated by the characterization of particular classes of mutations in the hisT gene: amber mutations, frame-shift mutations, and temperature-sensitive mutations that affect repression but not growth. In addition, the class of semilethal mutations was selected for but not found.

Bibliography

Chang, G. W., Roth, J. R., & Ames, B. N. (1971). Histidine Regulation in Salmonella typhimurium VIII. Mutations of the hisT Gene. Journal of Bacteriology, 108(1), 410â414.

Authors 3

George W. Chang (first)
John R. Roth (additional)
Bruce N. Ames (additional)

References 14 Referenced 43

Ames , B. N. , P. E. Hartman , and F. Jacob . 1963 . Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella . J. Mol. Biol. 7 : 23 - 42 . (10.1016/S0022-2836(63)80016-9) / J. Mol. Biol. / Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella by Ames B. N. (1963)
Ames , B. N. , and H. J. Whitfield , Jr. 1966 . Frameshift mutagenesis in Salmonella . Cold Spring Harbor Symp. Quant. Biol. 31 : 221 - 225 . (10.1101/SQB.1966.031.01.030) / Cold Spring Harbor Symp. Quant. Biol. / Frameshift mutagenesis in Salmonella by Ames B. N. (1966)
Anton , D. 1968 . Histidine regulatory mutants in Salmonella typhimurium. V. Two new classes of histidine regulatory mutants . J. Mol. Biol. 33 : 533 - 546 . (10.1016/0022-2836(68)90304-5) / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. V. Two new classes of histidine regulatory mutants by Anton D. (1968)
Brenner M. and B. N. Ames. 1971. The histidine operon and its regulation p. 349-387. In D. M. Greenberg and H. J. Vogel (ed.) Metabolic pathways vol. 5 Academic Press Inc. New York. (10.1016/B978-0-12-299255-1.50018-3)
Berkowitz , D. , J. M. Hushon , H. J. Whitfield , Jr. , J. Roth , and B. N. Ames . 1968 . Procedure for identifying nonsense mutations . J. Bacteriol. 96 : 215 - 220 . (10.1128/jb.96.1.215-220.1968) / J. Bacteriol. / Procedure for identifying nonsense mutations by Berkowitz D. (1968)
Chang , G. W. , D. Straus , and B. N. Ames . 1971 . Enriched selection of dominant mutations- histidine operator mutations . J. Bacteriol. 107 : 578 - 579 . (10.1128/jb.107.2.578-579.1971) / J. Bacteriol. / Enriched selection of dominant mutations- histidine operator mutations by Chang G. W. (1971)
Fink , G. R. , T. Klopotowski , and B. N. Ames . 1967 . Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constituitive mutants . J. Mol. Biol. 30 : 81 - 95 . / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constituitive mutants by Fink G. R. (1967)
Fink , G. R. , and J. R. Roth . 1968 . Histidine regulatory mutants in Salmonella typhimurium. VI. Dominance studies . J. Mol. Biol. 33 : 547 - 557 . (10.1016/0022-2836(68)90305-7) / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. VI. Dominance studies by Fink G. R. (1968)
Roth , J. , and B. N. Ames . 1966 . Histidine regulatory mutants in Salmonella typhimurium. II. Histidine regulatory mutants having an altered histidyl-tRNA synthetase . J. Mol. Biol. 22 : 325 - 334 . / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. II. Histidine regulatory mutants having an altered histidyl-tRNA synthetase by Roth J. (1966)
Roth , J. R. , D. Anton , and P. E. Hartman . 1966 . Histidine regulatory mutants in Salmonella typhimurium. 1. Isolation and general properties . J. Mol. Biol. 22 : 305 - 323 . (10.1016/0022-2836(66)90134-3) / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. 1. Isolation and general properties by Roth J. R. (1966)
Roth , J. R. , and P. E. Hartman . 1965 . Heterogeneity in P22 transducing particles . Virology 27 : 297 - 307 . (10.1016/0042-6822(65)90109-1) / Virology / Heterogeneity in P22 transducing particles by Roth J. R. (1965)
Silbert , D. F. , G. R. Fink , and B. N. Ames . 1966 . Histidine regulatory mutants in Salmonella typhimurium. III. A class of regulatory mutants deficient in tRNA for histidine . J. Mol. Biol. 22 : 335 - 347 . (10.1016/0022-2836(66)90136-7) / J. Mol. Biol. / Histidine regulatory mutants in Salmonella typhimurium. III. A class of regulatory mutants deficient in tRNA for histidine by Silbert D. F. (1966)
Smith , H. O. , and M. Levine . 1967 . A phage P22 gene controlling integration of prophage . Virology 31 : 207 - 216 . (10.1016/0042-6822(67)90164-X) / Virology / A phage P22 gene controlling integration of prophage by Smith H. O. (1967)
Vogel , H. J. , and D. M. Bonner . 1956 . Acetylornithase of E. coli: partial purification and some properties . J. Biol. Chem. 218 : 97 - 106 . (10.1016/S0021-9258(18)65874-0) / J. Biol. Chem. / Acetylornithase of E. coli: partial purification and some properties by Vogel H. J. (1956)

Dates

Type	When
Created	5 years, 7 months ago (Jan. 3, 2020, 9:32 a.m.)
Deposited	4 years, 2 months ago (June 1, 2021, 12:07 a.m.)
Indexed	2 months, 2 weeks ago (June 10, 2025, 4:26 p.m.)
Issued	53 years, 10 months ago (Oct. 1, 1971)
Published	53 years, 10 months ago (Oct. 1, 1971)
Published Print	53 years, 10 months ago (Oct. 1, 1971)

Funders 0

None

BibTeX

@article{Chang_1971, title={Histidine Regulation in Salmonella typhimurium VIII. Mutations of the hisT Gene}, volume={108}, ISSN={1098-5530}, url={http://dx.doi.org/10.1128/jb.108.1.410-414.1971}, DOI={10.1128/jb.108.1.410-414.1971}, number={1}, journal={Journal of Bacteriology}, publisher={American Society for Microbiology}, author={Chang, George W. and Roth, John R. and Ames, Bruce N.}, year={1971}, month=oct, pages={410–414} }

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