DOI: 10.1128/iai.69.2.1175-1177.2001. Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to <i>Bacillus anthracis</i> Lethal Toxin

Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin

10.1128/iai.69.2.1175-1177.2001

Crossref journal-article

American Society for Microbiology

Infection and Immunity (235)

Abstract

ABSTRACT We present evidence that Bacillus anthracis lethal toxin (LT) suppresses rather than induces proinflammatory cytokine production in macrophages. Suppression is observed with extremely low levels of LT and involves inhibition of transcription of cytokine messenger RNA. Thus, LT may contribute to anthrax pathogenesis by suppressing the inflammatory response.

Bibliography

Erwin, J. L., DaSilva, L. M., Bavari, S., Little, S. F., Friedlander, A. M., & Chanh, T. C. (2001). Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin. Infection and Immunity, 69(2), 1175â1177.

Authors 6

James L. Erwin (first)
Luis M. DaSilva (additional)
Sina Bavari (additional)
Stephen F. Little (additional)
Arthur M. Friedlander (additional)
Tran C. Chanh (additional)

References 7 Referenced 118

Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 6:01 a.m.)
Deposited	3 years, 6 months ago (March 4, 2022, 9:03 p.m.)
Indexed	1 year, 1 month ago (Aug. 3, 2024, 6:50 p.m.)
Issued	24 years, 7 months ago (Feb. 1, 2001)
Published	24 years, 7 months ago (Feb. 1, 2001)
Published Print	24 years, 7 months ago (Feb. 1, 2001)

Funders 0

None

BibTeX

@article{Erwin_2001, title={Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin}, volume={69}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.69.2.1175-1177.2001}, DOI={10.1128/iai.69.2.1175-1177.2001}, number={2}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Erwin, James L. and DaSilva, Luis M. and Bavari, Sina and Little, Stephen F. and Friedlander, Arthur M. and Chanh, Tran C.}, editor={Clements, J. D.}, year={2001}, month=feb, pages={1175–1177} }

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