DOI: 10.1128/iai.61.5.1694-1699.1993. Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola

Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola

10.1128/iai.61.5.1694-1699.1993

Crossref journal-article

American Society for Microbiology

Infection and Immunity (235)

Abstract

A 53-kDa protein from the outer sheath of the oral spirochete Treponema denticola was purified to homogeneity and shown to reconstitute channels in black lipid bilayer model membranes. The channel had a single-channel conductance of 1.8 nS in 0.1 M KCl, making this the largest porin channel observed to date (estimated diameter, 3.4 nm). Electron micrographs of 53-kDa-protein-containing outer sheaths of T. denticola showed a regular hexagonal array of darker staining pits.

Bibliography

Egli, C., Leung, W. K., MÃ¼ller, K. H., Hancock, R. E., & McBride, B. C. (1993). Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola. Infection and Immunity, 61(5), 1694â1699.

Authors 5

C Egli (first)
W K Leung (additional)
K H Müller (additional)
R E Hancock (additional)
B C McBride (additional)

References 0 Referenced 94

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 3, 2020, 8:29 a.m.)
Deposited	3 years, 5 months ago (March 4, 2022, 6:37 p.m.)
Indexed	2 months ago (June 27, 2025, 2:23 a.m.)
Issued	32 years, 3 months ago (May 1, 1993)
Published	32 years, 3 months ago (May 1, 1993)
Published Print	32 years, 3 months ago (May 1, 1993)

Funders 0

None

BibTeX

@article{Egli_1993, title={Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola}, volume={61}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.61.5.1694-1699.1993}, DOI={10.1128/iai.61.5.1694-1699.1993}, number={5}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Egli, C and Leung, W K and Müller, K H and Hancock, R E and McBride, B C}, year={1993}, month=may, pages={1694–1699} }

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