Abstract
Pseudomonas aeruginosa exoenzyme S ADP-ribosylates p21ras and several related proteins. ADP-ribosylation of p21ras does not alter interactions with guanine nucleotides. The ras-related GTP-binding proteins, including Rab3, Rab4, Ral, Rap1A, and Rap2, are also substrates; given these results, we propose a model for the role of exoenzyme S in pathogenesis.
Dates
Type | When |
---|---|
Created | 5 years, 7 months ago (Jan. 3, 2020, 8:46 a.m.) |
Deposited | 3 years, 5 months ago (March 4, 2022, 6:14 p.m.) |
Indexed | 1 year, 1 month ago (July 8, 2024, 1:50 a.m.) |
Issued | 33 years, 9 months ago (Nov. 1, 1991) |
Published | 33 years, 9 months ago (Nov. 1, 1991) |
Published Print | 33 years, 9 months ago (Nov. 1, 1991) |
@article{Coburn_1991, title={ADP-ribosylation of p21ras and related proteins by Pseudomonas aeruginosa exoenzyme S}, volume={59}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.59.11.4259-4262.1991}, DOI={10.1128/iai.59.11.4259-4262.1991}, number={11}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Coburn, J and Gill, D M}, year={1991}, month=nov, pages={4259–4262} }