DOI: 10.1128/iai.44.1.38-40.1984. Role of pili in the adherence of Pseudomonas aeruginosa to injured tracheal epithelium

Role of pili in the adherence of Pseudomonas aeruginosa to injured tracheal epithelium

10.1128/iai.44.1.38-40.1984

Crossref journal-article

American Society for Microbiology

Infection and Immunity (235)

Abstract

Pili have been demonstrated to be the adhesins of nonmucoid Pseudomonas aeruginosa for buccal cells. In this study, we examined their role in the adherence of both mucoid and nonmucoid strains to injured tracheal cells. Pili incubated with tracheal cells inhibited the adherence of a nonmucoid strain in a dose-dependent manner. Both homologous and heterologous pili inhibited this nonmucoid strain. Antibody against pili from the nonmucoid strain inhibited adherence of the homologous but not a heterologous strain. Pili failed to inhibit two mucoid strains, but inhibited nonmucoid variants derived from mucoid strains. These studies suggest that pili mediate the adherence of nonmucoid strains to injured tracheal cells but that they are not the final mediators of adherence of mucoid strains. It is also inferred that there are differences in the receptor for mucoid and nonmucoid strains.

Bibliography

Ramphal, R., Sadoff, J. C., Pyle, M., & Silipigni, J. D. (1984). Role of pili in the adherence of Pseudomonas aeruginosa to injured tracheal epithelium. Infection and Immunity, 44(1), 38â40.

Authors 4

R Ramphal (first)
J C Sadoff (additional)
M Pyle (additional)
J D Silipigni (additional)

References 0 Referenced 134

None

Dates

Type	When
Created	5 years, 8 months ago (Jan. 1, 2020, 1:01 a.m.)
Deposited	3 years, 6 months ago (March 4, 2022, 5:12 p.m.)
Indexed	3 days, 2 hours ago (Sept. 4, 2025, 9:47 a.m.)
Issued	41 years, 5 months ago (April 1, 1984)
Published	41 years, 5 months ago (April 1, 1984)
Published Print	41 years, 5 months ago (April 1, 1984)

Funders 0

None

BibTeX

@article{Ramphal_1984, title={Role of pili in the adherence of Pseudomonas aeruginosa to injured tracheal epithelium}, volume={44}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.44.1.38-40.1984}, DOI={10.1128/iai.44.1.38-40.1984}, number={1}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Ramphal, R and Sadoff, J C and Pyle, M and Silipigni, J D}, year={1984}, month=apr, pages={38–40} }

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