DOI: 10.1128/iai.38.3.1296-1298.1982. Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned-mouse model

Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned-mouse model

10.1128/iai.38.3.1296-1298.1982

Crossref journal-article

American Society for Microbiology

Infection and Immunity (235)

Abstract

To test the importance of flagella as a virulence factor, virulent strain Pseudomonas aeruginosa M-2 was mutagenized, and a Fla mutant was isolated. An M-2 Fla spontaneous motile revertant was isolated from M-2 Fla. The three strains were biochemically and morphologically identical. Assay of Fla in the burned-mouse model showed a severe loss of virulence. The Fla revertant was fully virulent. The importance of P. aeruginosa motility (flagella) for virulence in burns infections is indicated.

Bibliography

Montie, T. C., Doyle-Huntzinger, D., Craven, R. C., & Holder, I. A. (1982). Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned-mouse model. Infection and Immunity, 38(3), 1296â1298.

Authors 4

T C Montie (first)
D Doyle-Huntzinger (additional)
R C Craven (additional)
I A Holder (additional)

References 0 Referenced 122

None

Dates

Type	When
Created	5 years, 8 months ago (Jan. 2, 2020, 9:51 p.m.)
Deposited	3 years, 6 months ago (March 4, 2022, 5:06 p.m.)
Indexed	1 week, 5 days ago (Aug. 26, 2025, 2:22 a.m.)
Issued	42 years, 9 months ago (Dec. 1, 1982)
Published	42 years, 9 months ago (Dec. 1, 1982)
Published Print	42 years, 9 months ago (Dec. 1, 1982)

Funders 0

None

BibTeX

@article{Montie_1982, title={Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned-mouse model}, volume={38}, ISSN={1098-5522}, url={http://dx.doi.org/10.1128/iai.38.3.1296-1298.1982}, DOI={10.1128/iai.38.3.1296-1298.1982}, number={3}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Montie, T C and Doyle-Huntzinger, D and Craven, R C and Holder, I A}, year={1982}, month=dec, pages={1296–1298} }

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