DOI: 10.1128/aac.49.2.781-782.2005. The Biocide Triclosan Selects <i>Stenotrophomonas maltophilia</i> Mutants That Overproduce the SmeDEF Multidrug Efflux Pump

The Biocide Triclosan Selects Stenotrophomonas maltophilia Mutants That Overproduce the SmeDEF Multidrug Efflux Pump

10.1128/aac.49.2.781-782.2005

Crossref journal-article

American Society for Microbiology

Antimicrobial Agents and Chemotherapy (235)

Abstract

ABSTRACT The possibility that triclosan selects Stenotrophomonas maltophilia mutants overexpressing the multidrug resistance pump SmeDEF is analyzed. Five out of 12 triclosan-selected mutants were less susceptible to antibiotics than the wild-type strain and overproduced SmeDEF. Results are discussed in relation to current debates on the potential selection of antibiotic-resistant bacteria by household biocides.

Bibliography

Sanchez, P., Moreno, E., & Martinez, J. L. (2005). The Biocide Triclosan Selects Stenotrophomonas maltophilia Mutants That Overproduce the SmeDEF Multidrug Efflux Pump. Antimicrobial Agents and Chemotherapy, 49(2), 781â782.

Authors 3

Patricia Sanchez (first)
Eduardo Moreno (additional)
Jose L. Martinez (additional)

References 15 Referenced 98

10.1016/S1473-3099(03)00723-0
10.1128/AAC.44.11.3079-3086.2000
10.1128/AAC.45.6.1879-1881.2001
10.1128/AAC.41.5.1140
10.1093/jac/dkh074
Atlas R. M. 1993. Handbook of microbiological media. CRC Press Boca Raton Fla.
10.1128/AAC.45.2.428-432.2001
10.1128/JB.184.18.5036-5044.2002
Cole, E. C., R. M. Addison, J. R. Rubino, K. E. Leese, P. D. Dulaney, M. S. Newell, J. Wilkins, D. J. Gaber, T. Wineinger, and D. A. Criger. 2003. Investigation of antibiotic and antibacterial agent cross-resistance in target bacteria from homes of antibacterial product users and nonusers. J. Appl. Microbiol.95:664-676. (10.1046/j.1365-2672.2003.02022.x) / J. Appl. Microbiol. (2003)
10.1046/j.1365-2672.92.5s1.4.x
10.3201/eid0707.017705
10.1111/j.1574-6968.1998.tb13905.x
10.1093/jac/dkh171
10.1093/jac/dkf185
10.1128/AAC.45.12.3497-3503.2001

Dates

Type	When
Created	20 years, 7 months ago (Jan. 26, 2005, 5:04 p.m.)
Deposited	3 years, 6 months ago (Feb. 21, 2022, 1:44 p.m.)
Indexed	2 months, 1 week ago (June 26, 2025, 8:07 a.m.)
Issued	20 years, 7 months ago (Feb. 1, 2005)
Published	20 years, 7 months ago (Feb. 1, 2005)
Published Print	20 years, 7 months ago (Feb. 1, 2005)

Funders 0

None

BibTeX

@article{Sanchez_2005, title={The Biocide Triclosan Selects Stenotrophomonas maltophilia Mutants That Overproduce the SmeDEF Multidrug Efflux Pump}, volume={49}, ISSN={1098-6596}, url={http://dx.doi.org/10.1128/aac.49.2.781-782.2005}, DOI={10.1128/aac.49.2.781-782.2005}, number={2}, journal={Antimicrobial Agents and Chemotherapy}, publisher={American Society for Microbiology}, author={Sanchez, Patricia and Moreno, Eduardo and Martinez, Jose L.}, year={2005}, month=feb, pages={781–782} }

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