DOI: 10.1128/aac.24.5.713. Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers

Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers

10.1128/aac.24.5.713

Crossref journal-article

American Society for Microbiology

Antimicrobial Agents and Chemotherapy (235)

Abstract

In a double-blind, placebo-controlled study, self-administered intranasal human interferon alpha A produced by recombinant DNA technology was given both before and after virus challenge with a respiratory coronavirus. The incidence of colds, the severity of symptoms and signs, and virus replication were all reduced in subjects receiving interferon as compared with those given placebo.

Bibliography

Higgins, P. G., Phillpotts, R. J., Scott, G. M., Wallace, J., Bernhardt, L. L., & Tyrrell, D. A. (1983). Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers. Antimicrobial Agents and Chemotherapy, 24(5), 713â715.

Authors 6

P G Higgins (first)
R J Phillpotts (additional)
G M Scott (additional)
J Wallace (additional)
L L Bernhardt (additional)
D A Tyrrell (additional)

References 0 Referenced 71

None

Dates

Type	When
Created	13 years, 2 months ago (June 27, 2012, 8:03 p.m.)
Deposited	3 years, 6 months ago (Feb. 21, 2022, 9:28 a.m.)
Indexed	2 months, 3 weeks ago (June 11, 2025, 7:47 p.m.)
Issued	41 years, 10 months ago (Nov. 1, 1983)
Published	41 years, 10 months ago (Nov. 1, 1983)
Published Print	41 years, 10 months ago (Nov. 1, 1983)

Funders 0

None

BibTeX

@article{Higgins_1983, title={Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers}, volume={24}, ISSN={1098-6596}, url={http://dx.doi.org/10.1128/aac.24.5.713}, DOI={10.1128/aac.24.5.713}, number={5}, journal={Antimicrobial Agents and Chemotherapy}, publisher={American Society for Microbiology}, author={Higgins, P G and Phillpotts, R J and Scott, G M and Wallace, J and Bernhardt, L L and Tyrrell, D A}, year={1983}, month=nov, pages={713–715} }

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