DOI: 10.1126/science.aan7904. In situ architecture, function, and evolution of a contractile injection system

In situ architecture, function, and evolution of a contractile injection system

10.1126/science.aan7904

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Identification of a new injection system To interact with other cells, bacteria use contractile machines that function similarly to membrane-puncturing bacteriophages. The so-called type 6 secretion system (T6SS) functions from inside a bacterial cell. Böck et al. used modern electron microscopy methods and functional assays to resolve the structure and function of a T6SS in the cellular context. They identified three modules and showed large-scale structural changes upon firing. T6SSs are organized in multibarrel gun-like arrays and may contribute to the survival of bacteria inside their host. Science , this issue p. 713

Bibliography

BÃ¶ck, D., Medeiros, J. M., Tsao, H.-F., Penz, T., Weiss, G. L., Aistleitner, K., Horn, M., & Pilhofer, M. (2017). In situ architecture, function, and evolution of a contractile injection system. Science, 357(6352), 713â717.

Authors 8

Désirée Böck (first)
João M. Medeiros (additional)
Han-Fei Tsao (additional)
Thomas Penz (additional)
Gregor L. Weiss (additional)
Karin Aistleitner (additional)
Matthias Horn (additional)
Martin Pilhofer (additional)

References 43 Referenced 148

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Dates

Type	When
Created	8 years ago (Aug. 17, 2017, 2 p.m.)
Deposited	1 year, 7 months ago (Jan. 15, 2024, 12:30 p.m.)
Indexed	2 days ago (Aug. 20, 2025, 8:52 a.m.)
Issued	8 years ago (Aug. 18, 2017)
Published	8 years ago (Aug. 18, 2017)
Published Print	8 years ago (Aug. 18, 2017)

Funders 6

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BibTeX

@article{B_ck_2017, title={In situ architecture, function, and evolution of a contractile injection system}, volume={357}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.aan7904}, DOI={10.1126/science.aan7904}, number={6352}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Böck, Désirée and Medeiros, João M. and Tsao, Han-Fei and Penz, Thomas and Weiss, Gregor L. and Aistleitner, Karin and Horn, Matthias and Pilhofer, Martin}, year={2017}, month=aug, pages={713–717} }

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  "container-title-short": "Science",
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}