Conserved Structures and Diversity of Functions of RNA-Binding Proteins
10.1126/science.8036511
Crossref journal-article
American Association for the Advancement of Science (AAAS)
Science (221)
Abstract

In eukaryotic cells, a multitude of RNA-binding proteins play key roles in the posttranscriptional regulation of gene expression. Characterization of these proteins has led to the identification of several RNA-binding motifs, and recent experiments have begun to illustrate how several of them bind RNA. The significance of these interactions is reflected in the recent discoveries that several human and other vertebrate genetic disorders are caused by aberrant expression of RNA-binding proteins. The major RNA-binding motifs are described and examples of how they may function are given.

Bibliography

Burd, C. G., & Dreyfuss, G. (1994). Conserved Structures and Diversity of Functions of RNA-Binding Proteins. Science, 265(5172), 615–621.

Authors 2 University of Pennsylvania
  1. Christopher G. Burd (first) University of Pennsylvania
  2. Gideon Dreyfuss (additional) University of Pennsylvania
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Dates
Type When
Created 18 years, 10 months ago (Oct. 5, 2006, 4:01 p.m.)
Deposited 1 year, 7 months ago (Jan. 14, 2024, 6:04 p.m.)
Indexed 19 hours, 50 minutes ago (Aug. 29, 2025, 6:05 a.m.)
Issued 31 years, 1 month ago (July 29, 1994)
Published 31 years, 1 month ago (July 29, 1994)
Published Print 31 years, 1 month ago (July 29, 1994)
Funders 0

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@article{Burd_1994, title={Conserved Structures and Diversity of Functions of RNA-Binding Proteins}, volume={265}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.8036511}, DOI={10.1126/science.8036511}, number={5172}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Burd, Christopher G. and Dreyfuss, Gideon}, year={1994}, month=jul, pages={615–621} }