DOI: 10.1126/science.7973704. A Phase of Liposomes with Entangled Tubular Vesicles

A Phase of Liposomes with Entangled Tubular Vesicles

10.1126/science.7973704

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

An equilibrium phase belonging to the family of bilayer liposomes in ternary mixtures of dimyristoylphosphatidylcholine (DMPC), water, and geraniol (a biological alcohol derived from oil-soluble vitamins that acts as a cosurfactant) has been identified. Electron and optical microscopy reveal the phase, labeled L tv , to be composed of highly entangled tubular vesicles. In situ x-ray diffraction confirms that the tubule walls are multilamellar with the lipids in the chain-melted state. Macroscopic observations show that the L tv phase coexists with the well-known L 4 phase of spherical vesicles and a bulk L α phase. However, the defining characteristic of the L tv phase is the Weissenberg rod climbing effect under shear, which results from its polymer-like entangled microstructure.

Bibliography

Chiruvolu, S., Warriner, H. E., Naranjo, E., Idziak, S. H. J., RÃ¤dler, J., Plano, R. J., Zasadzinski, J. A., & Safinya, C. R. (1994). A Phase of Liposomes with Entangled Tubular Vesicles. Science, 266(5188), 1222â1225.

Authors 8

Shivkumar Chiruvolu (first)
Heidi E. Warriner (additional)
Edward Naranjo (additional)
Stefan H. J. Idziak (additional)
Joachim Rädler (additional)
Robert J. Plano (additional)
Joseph A. Zasadzinski (additional)
Cyrus R. Safinya (additional)

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Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 8:01 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 11:19 p.m.)
Indexed	1 year ago (Aug. 10, 2024, 1:12 a.m.)
Issued	30 years, 9 months ago (Nov. 18, 1994)
Published	30 years, 9 months ago (Nov. 18, 1994)
Published Print	30 years, 9 months ago (Nov. 18, 1994)

Funders 0

None

BibTeX

@article{Chiruvolu_1994, title={A Phase of Liposomes with Entangled Tubular Vesicles}, volume={266}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.7973704}, DOI={10.1126/science.7973704}, number={5188}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Chiruvolu, Shivkumar and Warriner, Heidi E. and Naranjo, Edward and Idziak, Stefan H. J. and Rädler, Joachim and Plano, Robert J. and Zasadzinski, Joseph A. and Safinya, Cyrus R.}, year={1994}, month=nov, pages={1222–1225} }

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