DOI: 10.1126/science.7939717. Role of Oocyte Position in Establishment of Anterior-Posterior Polarity in <i>Drosophila</i>

Role of Oocyte Position in Establishment of Anterior-Posterior Polarity in Drosophila

10.1126/science.7939717

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The polarized microtubule cytoskeleton of the Drosophila oocyte directs the localization of the maternal determinants which establish the anterior-posterior (AP) axis of the embryo. Because the formation of this microtubule array is dependent on signals from the follicle cells that surround the oocyte, it has been proposed that AP polarity originates in the follicle cells. Here it is shown that the movement of the oocyte to the posterior of the egg chamber early in oogenesis determines AP polarity in the follicle cell layer, and also in the oocyte. Moreover, the generation of AP asymmetry requires signaling from the germ line to the soma and back again.

Bibliography

GonzÃ¡lez-Reyes, A., & St Johnston, D. (1994). Role of Oocyte Position in Establishment of Anterior-Posterior Polarity in Drosophila. Science, 266(5185), 639â642.

Authors 2

Acaimo González-Reyes (first)
Daniel St Johnston (additional)

References 27 Referenced 99

BERLETH, T, THE ROLE OF LOCALIZATION OF BICOID RNA IN ORGANIZING THE ANTERIOR PATTERN OF THE DROSOPHILA EMBRYO, EMBO JOURNAL 7: 1749 (1988). (10.1002/j.1460-2075.1988.tb03004.x) / EMBO JOURNAL (1988)
Chasan, R., The Development of Drosophila melanogaster 1: 387 (1993). / The Development of Drosophila melanogaster (1993)
CHEUNG, H.K., EVIDENCE FOR A HIGHLY SELECTIVE RNA TRANSPORT-SYSTEM AND ITS ROLE IN ESTABLISHING THE DORSOVENTRAL AXIS OF THE DROSOPHILA EGG, DEVELOPMENT 114: 653 (1992). (10.1242/dev.114.3.653) / DEVELOPMENT (1992)
CHOU, T.B., AUTOSOMAL P[OVO(D1)] DOMINANT FEMALE-STERILE INSERTIONS IN DROSOPHILA AND THEIR USE IN GENERATING GERM-LINE CHIMERAS, DEVELOPMENT 119: 1359 (1993). (10.1242/dev.119.4.1359) / DEVELOPMENT (1993)
CLARK, I, TRANSIENT POSTERIOR LOCALIZATION OF A KINESIN FUSION PROTEIN REFLECTS ANTEROPOSTERIOR POLARITY OF THE DROSOPHILA OOCYTE, CURRENT BIOLOGY 4: 289 (1994). (10.1016/S0960-9822(00)00068-3) / CURRENT BIOLOGY (1994)
EPHRUSSI, A, OSKAR ORGANIZES THE GERM PLASM AND DIRECTS LOCALIZATION OF THE POSTERIOR DETERMINANT NANOS, CELL 66: 37 (1991). (10.1016/0092-8674(91)90137-N) / CELL (1991)
EPHRUSSI, A, INDUCTION OF GERM-CELL FORMATION BY OSKAR, NATURE 358: 387 (1992). (10.1038/358387a0) / NATURE (1992)
GINIGER, E, TRACING NEURONS WITH A KINESIN-BETA-GALACTOSIDASE FUSION PROTEIN, ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY 202: 112 (1993). (10.1007/BF00636536) / ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY (1993)
GONZALEZREYES A unpublished data.
GOODE, S, THE NEUROGENIC LOCUS BRAINIAC COOPERATES WITH THE DROSOPHILA EGF RECEPTOR TO ESTABLISH THE OVARIAN FOLLICLE AND TO DETERMINE ITS DORSAL-VENTAL POLARITY, DEVELOPMENT 116: 177 (1992). (10.1242/dev.116.1.177) / DEVELOPMENT (1992)
10.1038/366560a0
JOHNSTON, D.S., CELL 68: 201 (1992). (10.1016/0092-8674(92)90466-P) / CELL (1992)
KIMHA, J, OSKAR MESSENGER-RNA IS LOCALIZED TO THE POSTERIOR POLE OF THE DROSOPHILA OOCYTE, CELL 66: 23 (1991). (10.1016/0092-8674(91)90136-M) / CELL (1991)
LOHSSCHARDIN, M, W ROUX ARCH DEV BIOL 191: 28 (1982). (10.1007/BF00848543) / W ROUX ARCH DEV BIOL (1982)
Mahowald, A. P., The Genetics and Biology of Drosophila 2d: 141 (1980). / The Genetics and Biology of Drosophila (1980)
10.1016/0092-8674(92)90265-E
NEUMANSILBERBER.FS, THE DROSOPHILA DORSOVENTRAL PATTERNING GENE GURKEN PRODUCES A DORSALLY LOCALIZED RNA AND ENCODES A TGF-ALPHA-LIKE PROTEIN, CELL 75: 165 (1993). (10.1016/S0092-8674(05)80093-5) / CELL (1993)
PEIFER, M, A ROLE FOR THE DROSOPHILA SEGMENT POLARITY GENE ARMADILLO IN CELL-ADHESION AND CYTOSKELETAL INTEGRITY DURING OOGENESIS, DEVELOPMENT 118: 1191 (1993). (10.1242/dev.118.4.1191) / DEVELOPMENT (1993)
POKRYWKA, N.J., MICROTUBULES MEDIATE THE LOCALIZATION OF BICOID RNA DURING DROSOPHILA OOGENESIS, DEVELOPMENT 113: 55 (1991). / DEVELOPMENT (1991)
RUOHOLA, H, ROLE OF NEUROGENIC GENES IN ESTABLISHMENT OF FOLLICLE CELL FATE AND OOCYTE POLARITY DURING OOGENESIS IN DROSOPHILA, CELL 66: 433 (1991). (10.1016/0092-8674(81)90008-8) / CELL (1991)
RUOHOLABAKER, H, THE ROLE OF GENE CASSETTES IN AXIS FORMATION DURING DROSOPHILA OOGENESIS, TRENDS IN GENETICS 10: 89 (1994). (10.1016/0168-9525(94)90231-3) / TRENDS IN GENETICS (1994)
Spradling, A. C., The Development of Drosophila melanogaster 1: 1 (1993). / The Development of Drosophila melanogaster (1993)
STJOHNSTON, D, STAUFEN, A GENE REQUIRED TO LOCALIZE MATERNAL RNAS IN THE DROSOPHILA EGG, CELL 66: 51 (1991). (10.1016/0092-8674(91)90138-O) / CELL (1991)
STJOHNSTON, D, MULTIPLE STEPS IN THE LOCALIZATION OF BICOID RNA TO THE ANTERIOR POLE OF THE DROSOPHILA OOCYTE, DEVELOPMENT 107: 13 (1989). (10.1242/dev.107.Supplement.13) / DEVELOPMENT (1989)
TEARLE, R, DROSOPHILA INFORMATION SERVICE 66: 209 (1987). / DROSOPHILA INFORMATION SERVICE (1987)
THEURKAUF, W.E., REORGANIZATION OF THE CYTOSKELETON DURING DROSOPHILA OOGENESIS - IMPLICATIONS FOR AXIS SPECIFICATION AND INTERCELLULAR TRANSPORT, DEVELOPMENT 115: 923 (1992). (10.1242/dev.115.4.923) / DEVELOPMENT (1992)
10.1016/0092-8674(93)90397-9

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 8:01 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 11:15 p.m.)
Indexed	3 weeks, 4 days ago (Aug. 6, 2025, 8:19 a.m.)
Issued	30 years, 10 months ago (Oct. 28, 1994)
Published	30 years, 10 months ago (Oct. 28, 1994)
Published Print	30 years, 10 months ago (Oct. 28, 1994)

Funders 0

None

BibTeX

@article{Gonz_lez_Reyes_1994, title={Role of Oocyte Position in Establishment of Anterior-Posterior Polarity in Drosophila}, volume={266}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.7939717}, DOI={10.1126/science.7939717}, number={5185}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={González-Reyes, Acaimo and St Johnston, Daniel}, year={1994}, month=oct, pages={639–642} }

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