DOI: 10.1126/science.7528445. A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerases

A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerases

10.1126/science.7528445

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Bibliography

Steitz, T. A., Smerdon, S. J., JÃ¤ger, J., & Joyce, C. M. (1994). A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerases. Science, 266(5193), 2022â2025.

Authors 4

T. A. Steitz (first)
S. J. Smerdon (additional)
J. Jäger (additional)
C. M. Joyce (additional)

References 26 Referenced 240

ANDERSON, J, COCRYSTALS OF THE DNA-BINDING DOMAIN OF PHAGE-434 REPRESSOR AND A SYNTHETIC PHAGE 434 OPERATOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 1307 (1984). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES (1984)
BEESE, L.S., STRUCTURAL BASIS FOR THE 3'-5' EXONUCLEASE ACTIVITY OF ESCHERICHIA-COLI DNA-POLYMERASE-I - A 2 METAL-ION MECHANISM, EMBO JOURNAL 10: 25 (1991). (10.1002/j.1460-2075.1991.tb07917.x) / EMBO JOURNAL (1991)
10.1126/science.8469987
BEESE L.S. unpublished data.
DAVIES, J.F., 2.3-ANGSTROM CRYSTAL-STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE-BETA, CELL 76: 1123 (1994). (10.1016/0092-8674(94)90388-3) / CELL (1994)
DERBYSHIRE, V, THE 3'-5' EXONUCLEASE OF DNA-POLYMERASE-I OF ESCHERICHIA-COLI - CONTRIBUTION OF EACH AMINO-ACID AT THE ACTIVE-SITE TO THE REACTION, EMBO JOURNAL 10: 17 (1991). (10.1002/j.1460-2075.1991.tb07916.x) / EMBO JOURNAL (1991)
FREEMONT, P.S., COCRYSTAL STRUCTURE OF AN EDITING COMPLEX OF KLENOW FRAGMENT WITH DNA, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85: 8924 (1988). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1988)
HENDERSON, R, ALPHA-CHYMOTRYPSIN - WHAT CAN WE LEARN ABOUT CATALYSIS FROM X-RAY-DIFFRACTION, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 36: 63 (1971). / COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (1971)
JACOBOMOLINA, A, CRYSTAL-STRUCTURE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE COMPLEXED WITH DOUBLE-STRANDED DNA AT 3.0 ANGSTROM RESOLUTION SHOWS BENT DNA, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90: 6320 (1993). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1993)
JOYCE, C.M., FUNCTION AND STRUCTURE RELATIONSHIPS IN DNA-POLYMERASES, ANNUAL REVIEW OF BIOCHEMISTRY 63: 777 (1994). (10.1146/annurev.bi.63.070194.004021) / ANNUAL REVIEW OF BIOCHEMISTRY (1994)
JOYCE, C.M., DNA-POLYMERASE-I - FROM CRYSTAL-STRUCTURE TO FUNCTION VIA GENETICS, TRENDS IN BIOCHEMICAL SCIENCES 12: 288 (1987). (10.1016/0968-0004(87)90143-5) / TRENDS IN BIOCHEMICAL SCIENCES (1987)
KIM, E.E., REACTION-MECHANISM OF ALKALINE-PHOSPHATASE BASED ON CRYSTAL-STRUCTURES - 2-METAL ION CATALYSIS, JOURNAL OF MOLECULAR BIOLOGY 218: 449 (1991). (10.1016/0022-2836(91)90724-K) / JOURNAL OF MOLECULAR BIOLOGY (1991)
10.1126/science.1377403
METZGER, W, HYDROXYL RADICAL FOOTPRINT ANALYSIS OF HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE TEMPLATE.PRIMER COMPLEXES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90: 5909 (1993). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1993)
10.1021/bi00434a028
OLLIS, D.L., STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA-COLI DNA-POLYMERASE-I COMPLEXED WITH DTMP, NATURE 313: 762 (1985). (10.1038/313762a0) / NATURE (1985)
10.1126/science.7516580
RASKIN, C.A., SUBSTITUTION OF A SINGLE BACTERIOPHAGE-T3 RESIDUE IN BACTERIOPHAGE-T7 RNA-POLYMERASE AT POSITION-748 RESULTS IN A SWITCH IN PROMOTER SPECIFICITY, JOURNAL OF MOLECULAR BIOLOGY 228: 506 (1992). (10.1016/0022-2836(92)90838-B) / JOURNAL OF MOLECULAR BIOLOGY (1992)
ROBERTUS, J.D., SUBTILISIN - STEREOCHEMICAL MECHANISM INVOLVING TRANSITION-STATE STABILIZATION, BIOCHEMISTRY 11: 4293 (1972). (10.1021/bi00773a016) / BIOCHEMISTRY (1972)
10.1126/science.2479982
SASTRY, S.S., STUDIES ON THE INTERACTION OF T7 RNA-POLYMERASE WITH A DNA-TEMPLATE CONTAINING A SITE-SPECIFICALLY PLACED PSORALEN CROSS-LINK .1. CHARACTERIZATION OF ELONGATION COMPLEXES, JOURNAL OF MOLECULAR BIOLOGY 221: 1091 (1991). / JOURNAL OF MOLECULAR BIOLOGY (1991)
10.1126/science.7516581
SOUSA, R, CRYSTAL-STRUCTURE OF BACTERIOPHAGE-T7 RNA-POLYMERASE AT 3.3-ANGSTROM RESOLUTION, NATURE 364: 593 (1993). (10.1038/364593a0) / NATURE (1993)
STEITZ, T.A., DNA-DEPENDENT AND RNA-DEPENDENT DNA-POLYMERASES, CURRENT OPINION IN STRUCTURAL BIOLOGY 3: 31 (1993). (10.1016/0959-440X(93)90198-T) / CURRENT OPINION IN STRUCTURAL BIOLOGY (1993)
STEITZ, T.A., A GENERAL 2-METAL-ION MECHANISM FOR CATALYTIC RNA, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90: 6498 (1993). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1993)
WRIGHT, C.S., STRUCTURE OF SUBTILISIN BPNS' AT 2.5 A RESOLUTION, NATURE 221: 235 (1969). (10.1038/221235a0) / NATURE (1969)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 8:01 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 11:27 p.m.)
Indexed	1 week, 5 days ago (Aug. 20, 2025, 9:08 a.m.)
Issued	30 years, 8 months ago (Dec. 23, 1994)
Published	30 years, 8 months ago (Dec. 23, 1994)
Published Print	30 years, 8 months ago (Dec. 23, 1994)

Funders 0

None

BibTeX

@article{Steitz_1994, title={A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerases}, volume={266}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.7528445}, DOI={10.1126/science.7528445}, number={5193}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Steitz, T. A. and Smerdon, S. J. and Jäger, J. and Joyce, C. M.}, year={1994}, month=dec, pages={2022–2025} }

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