DOI: 10.1126/science.7433974. Nucleosome Cores Have Two Specific Binding Sites for Nonhistone Chromosomal Proteins HMG 14 and HMG 17

Nucleosome Cores Have Two Specific Binding Sites for Nonhistone Chromosomal Proteins HMG 14 and HMG 17

10.1126/science.7433974

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The binding of HMG 14 (or 17) to nucleosome cores produces two major additional bands on nondenaturing polyacrylamide gels. Bound HMG 14 alters the relative densities of the end-labeled DNA fragment distribution produced by deoxyribonuclease I digestion of reconstructed poly(deoxyadenylate-deoxythymidylate) nucleosome cores. These results indicate nucleosome cores have two specific binding sites for HMG 14 (or 17).

Bibliography

Mardian, J. K. W., Paton, A. E., Bunick, G. J., & Olins, D. E. (1980). Nucleosome Cores Have Two Specific Binding Sites for Nonhistone Chromosomal Proteins HMG 14 and HMG 17. Science, 209(4464), 1534â1536.

Authors 4

James K. W. Mardian (first)
Arthur E. Paton (additional)
Gerard J. Bunick (additional)
Donald E. Olins (additional)

References 24 Referenced 147

ABERCROMBIE, B.D., STUDIES ON CONFORMATIONAL PROPERTIES OF HIGH-MOBILITY-GROUP CHROMOSOMAL PROTEIN HMG 17 AND ITS INTERACTION WITH DNA, EUROPEAN JOURNAL OF BIOCHEMISTRY 84: 173 (1978). (10.1111/j.1432-1033.1978.tb12154.x) / EUROPEAN JOURNAL OF BIOCHEMISTRY (1978)
ALBRIGHT, S.C., SUBUNIT STRUCTURES OF DIFFERENT ELECTROPHORETIC FORMS OF NUCLEOSOMES, JOURNAL OF BIOLOGICAL CHEMISTRY 255: 3673 (1980). (10.1016/S0021-9258(19)85757-5) / JOURNAL OF BIOLOGICAL CHEMISTRY (1980)
BRYAN, P.N., CORE NUCLEOSOMES BY DIGESTION OF RECONSTRUCTED HISTONE-DNA COMPLEXES, NUCLEIC ACIDS RESEARCH 6: 1449 (1979). (10.1093/nar/6.4.1449) / NUCLEIC ACIDS RESEARCH (1979)
DIETERICH, A.E., SALT-INDUCED STRUCTURAL-CHANGES OF NUCLEOSOME CORE PARTICLES, JOURNAL OF MOLECULAR BIOLOGY 129: 587 (1979). (10.1016/0022-2836(79)90470-4) / JOURNAL OF MOLECULAR BIOLOGY (1979)
FELSENFELD, G, CHROMATIN, NATURE 271: 115 (1978). (10.1038/271115a0) / NATURE (1978)
10.1038/269029a0
GOODWIN, G.H., CELL NUCLEUS 6: 181 (1978). / CELL NUCLEUS (1978)
GOODWIN, G.H., ANALYSIS OF THE HIGH MOBILITY GROUP PROTEINS ASSOCIATED WITH SALT-SOLUBLE NUCLEOSOMES, NUCLEIC ACIDS RESEARCH 7: 1815 (1979). (10.1093/nar/7.7.1815) / NUCLEIC ACIDS RESEARCH (1979)
GORDON, V.C., CONFORMATIONAL-CHANGES OF CHROMATIN SUBUNIT, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75: 660 (1978). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1978)
LEVY, W.B., SUBSET OF TROUT TESTIS NUCLEOSOMES ENRICHED IN TRANSCRIBED DNA SEQUENCES CONTAINS HIGH MOBILITY GROUP PROTEINS AS MAJOR STRUCTURAL COMPONENTS, JOURNAL OF BIOLOGICAL CHEMISTRY 254: 609 (1979). (10.1016/S0021-9258(17)37849-3) / JOURNAL OF BIOLOGICAL CHEMISTRY (1979)
LUTTER, L.C., KINETIC-ANALYSIS OF DEOXYRIBONUCLEASE-I CLEAVAGES IN NUCLEOSOME CORE - EVIDENCE FOR A DNA SUPERHELIX, JOURNAL OF MOLECULAR BIOLOGY 124: 391 (1978). (10.1016/0022-2836(78)90306-6) / JOURNAL OF MOLECULAR BIOLOGY (1978)
LUTTER, L.C., PRECISE LOCATION OF DNASE-I CUTTING SITES IN THE NUCLEOSOME CORE DETERMINED BY HIGH-RESOLUTION GEL-ELECTROPHORESIS, NUCLEIC ACIDS RESEARCH 6: 41 (1979). (10.1093/nar/6.1.41) / NUCLEIC ACIDS RESEARCH (1979)
MARDIAN JKW UNPUBLISHED.
MATHEW, CGP, COMPARISON OF THE HIGH MOBILITY GROUP NON-HISTONE CHROMATIN PROTEIN-HMG-2 IN CHICKEN THYMUS AND ERYTHROCYTES, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 87: 1243 (1979). (10.1016/S0006-291X(79)80040-6) / BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (1979)
10.1073/pnas.74.2.560
OLINS, A.L., CHROMATIN-NU BODIES - ISOLATION, SUBFRACTIONATION AND PHYSICAL CHARACTERIZATION, NUCLEIC ACIDS RESEARCH 3: 3271 (1976). (10.1093/nar/3.12.3271) / NUCLEIC ACIDS RESEARCH (1976)
RABBANI, A, HIGH MOBILITY GROUP NON-HISTONE CHROMOSOMAL-PROTEINS FROM CHICKEN ERYTHROCYTES, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 81: 351 (1978). (10.1016/0006-291X(78)91540-1) / BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (1978)
RHODES, D, NUCLEOSOME CORES RECONSTITUTED FROM POLY (DA-DT) AND THE OCTAMER OF HISTONES, NUCLEIC ACIDS RESEARCH 6: 1805 (1979). (10.1093/nar/6.5.1805) / NUCLEIC ACIDS RESEARCH (1979)
SIMPSON, R.T., CHROMATIN AND CORE PARTICLES FORMED FROM THE INNER HISTONES AND SYNTHETIC POLYDEOXYRIBONUCLEOTIDES OF DEFINED SEQUENCE, NUCLEIC ACIDS RESEARCH 6: 1387 (1979). (10.1093/nar/6.4.1387) / NUCLEIC ACIDS RESEARCH (1979)
WALKER, J.M., PRIMARY STRUCTURE OF THE NUCLEOSOME-ASSOCIATED CHROMOSOMAL PROTEIN HMG-14, FEBS LETTERS 100: 394 (1979). (10.1016/0014-5793(79)80378-6) / FEBS LETTERS (1979)
10.1126/science.948749
WEISBROD, S, INTERACTION OF HMG 14 AND 17 WITH ACTIVELY TRANSCRIBED GENES, CELL 19: 289 (1980). (10.1016/0092-8674(80)90410-9) / CELL (1980)
WEISBROD, S, ISOLATION OF A SUBCLASS OF NUCLEAR PROTEINS RESPONSIBLE FOR CONFERRING A DNASE I-SENSITIVE STRUCTURE ON GLOBIN CHROMATIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76: 630 (1979). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1979)
ZAMA, M, NUCLEOSOME CONFORMATION - PH AND ORGANIC-SOLVENT EFFECTS, NUCLEIC ACIDS RESEARCH 5: 3881 (1978). (10.1093/nar/5.10.3881) / NUCLEIC ACIDS RESEARCH (1978)

Dates

Type	When
Created	18 years, 11 months ago (Oct. 5, 2006, 1:45 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 10:43 p.m.)
Indexed	1 day, 15 hours ago (Sept. 4, 2025, 9:24 a.m.)
Issued	44 years, 11 months ago (Sept. 26, 1980)
Published	44 years, 11 months ago (Sept. 26, 1980)
Published Print	44 years, 11 months ago (Sept. 26, 1980)

Funders 0

None

BibTeX

@article{Mardian_1980, title={Nucleosome Cores Have Two Specific Binding Sites for Nonhistone Chromosomal Proteins HMG 14 and HMG 17}, volume={209}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.7433974}, DOI={10.1126/science.7433974}, number={4464}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Mardian, James K. W. and Paton, Arthur E. and Bunick, Gerard J. and Olins, Donald E.}, year={1980}, month=sep, pages={1534–1536} }

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