DOI: 10.1126/science.6102412. Localization of Lysyl Oxidase in Hen Oviduct: Implications in Egg Shell Membrane Formation and Composition

Localization of Lysyl Oxidase in Hen Oviduct: Implications in Egg Shell Membrane Formation and Composition

10.1126/science.6102412

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Lysyl oxidase activity was found in the isthmus (the membrane-forming region) of the hen's oviduct in a copper-rich region proximal to the shell gland. Desmosine and isodesmosine, cross-linking compounds associated with mature elastin, were found in hydrolysates of the shell membrane, confirming the necessity for lysyl oxidase in its biosynthesis. Shell membranes from hens fed a copper-deficient diet or a diet supplemented with β-aminopropionitrile had a reduced content of desmosine and isodesmosine.

Bibliography

Harris, E. D., Blount, J. E., & Leach, R. M. (1980). Localization of Lysyl Oxidase in Hen Oviduct: Implications in Egg Shell Membrane Formation and Composition. Science, 208(4439), 55â56.

Authors 3

Edward D. Harris (first)
Johnie E. Blount (additional)
Roland M. Leach (additional)

References 14 Referenced 61

BALCH, D.A., A STUDY OF COMPOSITION OF HENS EGG-SHELL MEMBRANES, ANNALES DE BIOLOGIE ANIMALE BIOCHIMIE BIOPHYSIQUE 10: 13 (1970). (10.1051/rnd:19700601) / ANNALES DE BIOLOGIE ANIMALE BIOCHIMIE BIOPHYSIQUE (1970)
BARNETT, B.D., EFFECT OF BETA-AMINOPROPIONITRILE ON REPRODUCTION OF CHICKENS, PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 95: 101 (1957). (10.3181/00379727-95-23134) / PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE (1957)
BAUMGARTNER, S, COPPER DEFICIENCY IN LAYING HEN, JOURNAL OF NUTRITION 108: 804 (1978). (10.1093/jn/108.5.804) / JOURNAL OF NUTRITION (1978)
CALVERY, H.O., Some analyses of egg-shell keratin, JOURNAL OF BIOLOGICAL CHEMISTRY 100: 183 (1933). (10.1016/S0021-9258(18)75991-7) / JOURNAL OF BIOLOGICAL CHEMISTRY (1933)
CANDLISH, J.K., L-5-HYDROXYLYSINE AS A CONSTITUENT OF SHELL MEMBRANES OF HENS EGG, INTERNATIONAL JOURNAL OF PROTEIN RESEARCH 1: 299 (1969). (10.1111/j.1399-3011.1969.tb01654.x) / INTERNATIONAL JOURNAL OF PROTEIN RESEARCH (1969)
GREEN, R.A., RAPID PROCEDURE FOR ISOLATION OF POLYFUNCTIONAL AMINO-ACIDS IN ELASTIN, ANALYTICAL BIOCHEMISTRY 52: 538 (1973). (10.1016/0003-2697(73)90059-6) / ANALYTICAL BIOCHEMISTRY (1973)
HARRIS, E.D., CONNECTIVE-TISSUE AMINE OXIDASE .2. PURIFICATION AND PARTIAL CHARACTERIZATION OF LYSYL OXIDASE FROM CHICK AORTA, BIOCHIMICA ET BIOPHYSICA ACTA 341: 332 (1974). (10.1016/0005-2744(74)90226-5) / BIOCHIMICA ET BIOPHYSICA ACTA (1974)
LEACH, R.M., STUDIES ON MAJOR PROTEIN COMPONENT OF EGG-SHELL MEMBRANES, POULTRY SCIENCE 57: 1151 (1978). / POULTRY SCIENCE (1978)
MOCZAR, E, SEPARATION AND DETERMINATION OF CROSSLINKING AMINO-ACIDS OF ELASTIN BY HIGH-VOLTAGE PAPER-ELECTROPHORESIS, ANALYTICAL BIOCHEMISTRY 45: 422 (1972). (10.1016/0003-2697(72)90203-5) / ANALYTICAL BIOCHEMISTRY (1972)
MOOYOUNG, A.J., COPPER CONTENT OF ISTHMUS MUCOSA AND CERTAIN ORGANS OF DOMESTIC FOWL, PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 133: 497 (1970). (10.3181/00379727-133-34505) / PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE (1970)
PINNELL, S.R., CROSS-LINKING OF COLLAGEN AND ELASTIN - ENZYMATIC CONVERSION OF LYSINE IN PEPTIDE LINKAGE TO ALPHA-AMINOADIPIC-DELTA-SEMIALDEHYDE (ALLYSINE) BY AN EXTRACT FROM BONE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 61: 708 (1968). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1968)
SIEGEL, R.C., CROSS-LINKING OF COLLAGEN AND ELASTIN - PROPERTIES OF LYSYL OXIDASE, BIOCHEMISTRY 9: 4486 (1970). (10.1021/bi00825a004) / BIOCHEMISTRY (1970)
STARCHER, B.C., DETERMINATION OF ELASTIN CONTENT OF TISSUES BY MEASURING DESMOSINE AND ISODESMOSINE, ANALYTICAL BIOCHEMISTRY 79: 11 (1977). (10.1016/0003-2697(77)90372-4) / ANALYTICAL BIOCHEMISTRY (1977)
10.1126/science.180.4086.561

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 1:45 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 11:16 a.m.)
Indexed	2 days, 18 hours ago (Aug. 27, 2025, 12:09 p.m.)
Issued	45 years, 4 months ago (April 4, 1980)
Published	45 years, 4 months ago (April 4, 1980)
Published Print	45 years, 4 months ago (April 4, 1980)

Funders 0

None

BibTeX

@article{Harris_1980, title={Localization of Lysyl Oxidase in Hen Oviduct: Implications in Egg Shell Membrane Formation and Composition}, volume={208}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.6102412}, DOI={10.1126/science.6102412}, number={4439}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Harris, Edward D. and Blount, Johnie E. and Leach, Roland M.}, year={1980}, month=apr, pages={55–56} }

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