DOI: 10.1126/science.6095453. JC Virus Enhancer-Promoter Active in Human Brain Cells

JC Virus Enhancer-Promoter Active in Human Brain Cells

10.1126/science.6095453

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

A human papovavirus, JCV, is the etiologic agent of the fatal demyelinating disease, progressive multifocal leukoencephalopathy. The JCV 98-base-pair tandem repeats, located to the late side of the viral replication origin, were shown to be a transcriptional regulatory element with enhancer-like activity in human fetal glial cells. These tandem repeats share significant homology with the 82-nucleotide rat brain-specific identifier RNA sequence.

Bibliography

Kenney, S., Natarajan, V., Strike, D., Khoury, G., & Salzman, N. P. (1984). JC Virus Enhancer-Promoter Active in Human Brain Cells. Science, 226(4680), 1337â1339.

Authors 5

Shannon Kenney (first)
Venkatachala Natarajan (additional)
David Strike (additional)
George Khoury (additional)
Norman P. Salzman (additional)

References 26 Referenced 139

BANERJI, J, A LYMPHOCYTE-SPECIFIC CELLULAR ENHANCER IS LOCATED DOWNSTREAM OF THE JOINING REGION IN IMMUNOGLOBULIN HEAVY-CHAIN GENES, CELL 33: 729 (1983). (10.1016/0092-8674(83)90015-6) / CELL (1983)
BECKMAN, A.M., PROPAGATION AND PRIMARY ISOLATION OF PAPOVAVIRUS-JC IN EPITHELIAL-CELLS DERIVED FROM HUMAN-URINE, INFECTION AND IMMUNITY 38: 774 (1982). (10.1128/iai.38.2.774-777.1982) / INFECTION AND IMMUNITY (1982)
BENOIST, C, INVIVO SEQUENCE REQUIREMENTS OF THE SV40 EARLY PROMOTER REGION, NATURE 290: 304 (1981). (10.1038/290304a0) / NATURE (1981)
CHEN, ISY, LONG TERMINAL REPEATS OF HUMAN T-CELL LEUKEMIA VIRUS-II GENOME DETERMINE TARGET-CELL SPECIFICITY, NATURE 309: 276 (1984). (10.1038/309276a0) / NATURE (1984)
COLEMAN, D.V., A PROSPECTIVE-STUDY OF HUMAN POLYOMAVIRUS INFECTION IN PREGNANCY, JOURNAL OF INFECTIOUS DISEASES 142: 1 (1980). (10.1093/infdis/142.1.1) / JOURNAL OF INFECTIOUS DISEASES (1980)
DesGroseillers, L., Proceedings of the National Academy of Sciences of the United States of America 80: 4203 (1983). / Proceedings of the National Academy of Sciences of the United States of America (1983)
FAREED, G.C., MICROBIOLOGY+: 427 (1978). / MICROBIOLOGY+ (1978)
FRISQUE, R.J., NUCLEOTIDE-SEQUENCE OF THE REGION ENCOMPASSING THE JC-VIRUS ORIGIN OF DNA-REPLICATION, JOURNAL OF VIROLOGY 46: 170 (1983). (10.1128/jvi.46.1.170-176.1983) / JOURNAL OF VIROLOGY (1983)
GILLIES, S.D., A TISSUE-SPECIFIC TRANSCRIPTION ENHANCER ELEMENT IS LOCATED IN THE MAJOR INTRON OF A REARRANGED IMMUNOGLOBULIN HEAVY-CHAIN GENE, CELL 33: 717 (1983). (10.1016/0092-8674(83)90014-4) / CELL (1983)
GOAD, W.B., PATTERN-RECOGNITION IN NUCLEIC-ACID SEQUENCES .1. A GENERAL-METHOD FOR FINDING LOCAL HOMOLOGIES AND SYMMETRIES, NUCLEIC ACIDS RESEARCH 10: 247 (1982). (10.1093/nar/10.1.247) / NUCLEIC ACIDS RESEARCH (1982)
GORMAN, C.M., RECOMBINANT GENOMES WHICH EXPRESS CHLORAMPHENICOL ACETYLTRANSFERASE IN MAMMALIAN-CELLS, MOLECULAR AND CELLULAR BIOLOGY 2: 1044 (1982). / MOLECULAR AND CELLULAR BIOLOGY (1982)
10.1073/pnas.79.22.6777
10.1016/0042-6822(73)90341-3
Gruss, P., Proceedings of the National Academy of Sciences of the United States of America 78: 943 (1981). / Proceedings of the National Academy of Sciences of the United States of America (1981)
HOGAN, T.F., HUMAN POLYOMAVIRUS INFECTIONS WITH JC VIRUS AND BK VIRUS IN RENAL-TRANSPLANT PATIENTS, ANNALS OF INTERNAL MEDICINE 92: 373 (1980). (10.7326/0003-4819-92-3-373) / ANNALS OF INTERNAL MEDICINE (1980)
LAIMINS, L.A., CHARACTERIZATION OF ENHANCER ELEMENTS IN THE LONG TERMINAL REPEAT OF MOLONEY MURINE SARCOMA-VIRUS, JOURNAL OF VIROLOGY 49: 183 (1984). (10.1128/jvi.49.1.183-189.1984) / JOURNAL OF VIROLOGY (1984)
LENZ, J, DETERMINATION OF THE LEUKEMOGENICITY OF A MURINE RETROVIRUS BY SEQUENCES WITHIN THE LONG TERMINAL REPEAT, NATURE 308: 467 (1984). (10.1038/308467a0) / NATURE (1984)
MILNER, R.J., BRAIN-SPECIFIC GENES HAVE IDENTIFIER SEQUENCES IN THEIR INTRONS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 713 (1984). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES (1984)
PADGETT, B.L., JC VIRUS, A HUMAN POLYOMA-VIRUS ASSOCIATED WITH PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY - ADDITIONAL BIOLOGICAL CHARACTERISTICS AND ANTIGENIC RELATIONSHIPS, INFECTION AND IMMUNITY 15: 656 (1977). (10.1128/iai.15.2.656-662.1977) / INFECTION AND IMMUNITY (1977)
PADGETT, B.L., JC PAPOVAVIRUS IN PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY, JOURNAL OF INFECTIOUS DISEASES 133: 686 (1976). (10.1093/infdis/133.6.686) / JOURNAL OF INFECTIOUS DISEASES (1976)
PICARD, D, A LYMPHOCYTE-SPECIFIC ENHANCER IN THE MOUSE IMMUNOGLOBULIN KAPPA-GENE, NATURE 307: 80 (1984). (10.1038/307080a0) / NATURE (1984)
QUEEN, C, IMMUNOGLOBULIN GENE-TRANSCRIPTION IS ACTIVATED BY DOWNSTREAM SEQUENCE ELEMENTS, CELL 33: 741 (1983). (10.1016/0092-8674(83)90016-8) / CELL (1983)
10.1126/science.6314501
SUTCLIFFE, J, IDENTIFIER SEQUENCES ARE TRANSCRIBED SPECIFICALLY IN BRAIN, NATURE 308: 237 (1984). (10.1038/308237a0) / NATURE (1984)
TAKEMOTO, K, JC HUMAN PAPOVAVIRUS REPLICATION IN HUMAN AMNION CELLS, JOURNAL OF VIROLOGY 30: 384 (1979). (10.1128/jvi.30.1.384-389.1979) / JOURNAL OF VIROLOGY (1979)
WALKER, M.D., CELL-SPECIFIC EXPRESSION CONTROLLED BY THE 5'-FLANKING REGION OF INSULIN AND CHYMOTRYPSIN GENES, NATURE 306: 557 (1983). (10.1038/306557a0) / NATURE (1983)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 3:41 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 11:25 a.m.)
Indexed	11 months, 2 weeks ago (Sept. 13, 2024, 2:50 p.m.)
Issued	40 years, 8 months ago (Dec. 14, 1984)
Published	40 years, 8 months ago (Dec. 14, 1984)
Published Print	40 years, 8 months ago (Dec. 14, 1984)

Funders 0

None

BibTeX

@article{Kenney_1984, title={JC Virus Enhancer-Promoter Active in Human Brain Cells}, volume={226}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.6095453}, DOI={10.1126/science.6095453}, number={4680}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Kenney, Shannon and Natarajan, Venkatachala and Strike, David and Khoury, George and Salzman, Norman P.}, year={1984}, month=dec, pages={1337–1339} }

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