The Molecular Basis of Erythrocyte Shape
10.1126/science.3775380
Crossref journal-article
American Association for the Advancement of Science (AAAS)
Science (221)
Abstract

Recent discoveries about the molecular organization and physical properties of the mammalian erythrocyte membrane and its associated structural proteins can now be used to explain, and may eventually be used to predict, the shape of the erythrocyte. Such explanations are possible because the relatively few structural proteins of the erythrocyte are regularly distributed over the entire cytoplasmic surface of the cell membrane and because the well-understood topological associations of these proteins seem to be stable in comparison with the time required for the cell to change shape. These simplifications make the erythrocyte the first nonmuscle cell for which it will be possible to extend our knowledge of molecular interactions to the next hierarchical level of organization that deals with shape and shape transformations.

Bibliography

Elgsaeter, A., Stokke, B. T., Mikkelsen, A., & Branton, D. (1986). The Molecular Basis of Erythrocyte Shape. Science, 234(4781), 1217–1223.

Authors 4
  1. Arnljot Elgsaeter (first)
  2. Bjorn T. Stokke (additional)
  3. Arne Mikkelsen (additional)
  4. Daniel Branton (additional)
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Dates
Type When
Created 18 years, 10 months ago (Oct. 5, 2006, 4:28 p.m.)
Deposited 1 year, 7 months ago (Jan. 14, 2024, 5:20 a.m.)
Indexed 1 month, 3 weeks ago (June 30, 2025, 1:28 a.m.)
Issued 38 years, 8 months ago (Dec. 5, 1986)
Published 38 years, 8 months ago (Dec. 5, 1986)
Published Print 38 years, 8 months ago (Dec. 5, 1986)
Funders 0

None

@article{Elgsaeter_1986, title={The Molecular Basis of Erythrocyte Shape}, volume={234}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.3775380}, DOI={10.1126/science.3775380}, number={4781}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Elgsaeter, Arnljot and Stokke, Bjorn T. and Mikkelsen, Arne and Branton, Daniel}, year={1986}, month=dec, pages={1217–1223} }