DOI: 10.1126/science.3175637. Spontaneous Impulse Activity of Rat Retinal Ganglion Cells in Prenatal Life

Spontaneous Impulse Activity of Rat Retinal Ganglion Cells in Prenatal Life

10.1126/science.3175637

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The existence of spontaneous neural activity in mammalian retinal ganglion cells during prenatal life has long been suspected. This activity could play a key role in the refinement of retinal projections during development. Recordings in vivo from the retinas of rat fetuses between embryonic day 17 and 21 found action potentials in spontaneously active ganglion cells at all the ages studied.

Bibliography

Galli, L., & Maffei, L. (1988). Spontaneous Impulse Activity of Rat Retinal Ganglion Cells in Prenatal Life. Science, 242(4875), 90â91.

Authors 2

Lucia Galli (first)
Lamberto Maffei (additional)

References 12 Referenced 345

BUNT, S. M., DEVELOPMENTAL BRAIN RESEARCH 6: 149 (1983). (10.1016/0165-3806(83)90093-7) / DEVELOPMENTAL BRAIN RESEARCH (1983)
CRESPO, D, CHANGES IN THE NUMBERS OF OPTIC-NERVE FIBERS DURING LATE PRENATAL AND POSTNATAL-DEVELOPMENT IN THE ALBINO-RAT, DEVELOPMENTAL BRAIN RESEARCH 19: 129 (1985). (10.1016/0165-3806(85)90238-X) / DEVELOPMENTAL BRAIN RESEARCH (1985)
DUBIN, M.W., A ROLE FOR ACTION-POTENTIAL ACTIVITY IN THE DEVELOPMENT OF NEURONAL CONNECTIONS IN THE KITTEN RETINOGENICULATE PATHWAY, JOURNAL OF NEUROSCIENCE 6: 1021 (1986). (10.1523/JNEUROSCI.06-04-01021.1986) / JOURNAL OF NEUROSCIENCE (1986)
FITZGERALD, M, SPONTANEOUS AND EVOKED ACTIVITY OF FETAL PRIMARY AFFERENTS INVIVO, NATURE 326: 603 (1987). (10.1038/326603a0) / NATURE (1987)
FRANK, E, THE INFLUENCE OF NEURONAL-ACTIVITY ON PATTERNS OF SYNAPTIC CONNECTIONS, TRENDS IN NEUROSCIENCES 10: 188 (1987). (10.1016/0166-2236(87)90143-3) / TRENDS IN NEUROSCIENCES (1987)
LIPTON, S.A., BLOCKADE OF ELECTRICAL-ACTIVITY PROMOTES THE DEATH OF MAMMALIAN RETINAL GANGLION-CELLS IN CULTURE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 9774 (1986). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1986)
OLEARY, DDM, TOPOGRAPHIC TARGETING ERRORS IN THE RETINOCOLLICULAR PROJECTION AND THEIR ELIMINATION BY SELECTIVE GANGLION-CELL DEATH, JOURNAL OF NEUROSCIENCE 6: 3692 (1986). (10.1523/JNEUROSCI.06-12-03692.1986) / JOURNAL OF NEUROSCIENCE (1986)
OLEARY, DDM, TOPOGRAPHIC ORGANIZATION OF CERTAIN TECTAL AFFERENT AND EFFERENT CONNECTIONS CAN DEVELOP NORMALLY IN THE ABSENCE OF RETINAL INPUT, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80: 6131 (1983). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES (1983)
SHATZ, C. J., JOURNAL OF NEUROSCIENCE 4: 1378 (1984). (10.1523/JNEUROSCI.04-05-01378.1984) / JOURNAL OF NEUROSCIENCE (1984)
10.1126/science.3175636
STRYKER, M.P., INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 25 Supplement: 278 (1984). / INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (1984)
STRYKER, M.P., BINOCULAR IMPULSE BLOCKADE PREVENTS THE FORMATION OF OCULAR DOMINANCE COLUMNS IN CAT VISUAL-CORTEX, JOURNAL OF NEUROSCIENCE 6: 2117 (1986). (10.1523/JNEUROSCI.06-08-02117.1986) / JOURNAL OF NEUROSCIENCE (1986)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 5:21 p.m.)
Deposited	1 year, 7 months ago (Jan. 13, 2024, 4:19 p.m.)
Indexed	1 day, 1 hour ago (Aug. 29, 2025, 6:03 a.m.)
Issued	36 years, 10 months ago (Oct. 7, 1988)
Published	36 years, 10 months ago (Oct. 7, 1988)
Published Print	36 years, 10 months ago (Oct. 7, 1988)

Funders 0

None

BibTeX

@article{Galli_1988, title={Spontaneous Impulse Activity of Rat Retinal Ganglion Cells in Prenatal Life}, volume={242}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.3175637}, DOI={10.1126/science.3175637}, number={4875}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Galli, Lucia and Maffei, Lamberto}, year={1988}, month=oct, pages={90–91} }

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