DOI: 10.1126/science.302030. Control of a Cell Surface Major Glycoprotein by Epidermal Growth Factor

Control of a Cell Surface Major Glycoprotein by Epidermal Growth Factor

10.1126/science.302030

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

When the serum concentration of the culture medium is below 0.7 percent, 3T3 mouse cells lose most of their large external transformation sensitive (LETS) protein at the cell surface, Subsequent addition of epidermal growth factor results in the reappearance of massive fibrillar LETS protein networks on the surface of confluent 3T3 cells. Thirteen other hormones tested do not have this effect. It appears that epidermal growth factor can control the expression of LETS protein.

Bibliography

Chen, L. B., Gudor, R. C., Sun, T.-T., Chen, A. B., & Mosesson, M. W. (1977). Control of a Cell Surface Major Glycoprotein by Epidermal Growth Factor. Science, 197(4305), 776â778.

Authors 5

Lan Bo Chen (first)
Robert C. Gudor (additional)
Tung-Tien Sun (additional)
Anthony B. Chen (additional)
Michael W. Mosesson (additional)

References 24 Referenced 99

ARMELIN, H.A., PITUITARY EXTRACTS AND STEROID-HORMONES IN CONTROL 3T3-CELL GROWTH, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70: 2702 (1973). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1973)
CHEN, L.B., ALTERATION IN CELL-SURFACE LETS PROTEIN DURING MYOGENESIS, CELL 10: 393 (1977). (10.1016/0092-8674(77)90026-5) / CELL (1977)
CHEN, L.B., DETECTION OF LARGE EXTERNAL TRANSFORMATION-SENSITIVE PROTEIN ON SOME EPITHELIAL-CELLS, EXPERIMENTAL CELL RESEARCH 106: 39 (1977). (10.1016/0014-4827(77)90238-5) / EXPERIMENTAL CELL RESEARCH (1977)
CHEN, L.B., MITOGENIC ACTIVITY OF BLOOD COMPONENTS .1. THROMBIN AND PROTHROMBIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 72: 131 (1975). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1975)
CHEN, L.B., CORRELATION BETWEEN TUMOR INDUCTION AND LARGE EXTERNAL TRANSFORMATION SENSITIVE PROTEIN ON CELL-SURFACE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73: 3570 (1976). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1976)
CHEN L.B. UNPUBLISHED RESULTS.
COHEN, S, ISOLATION OF A MOUSE SUBMAXILLARY GLAND PROTEIN ACCELERATING INCISOR ERUPTION AND EYELID OPENING IN NEW-BORN ANIMAL, JOURNAL OF BIOLOGICAL CHEMISTRY 237: 1555 (1962). (10.1016/S0021-9258(19)83739-0) / JOURNAL OF BIOLOGICAL CHEMISTRY (1962)
GAHMBERG, C.G., CHANGES IN A SURFACE-LABELED GALACTOPROTEIN AND IN GLYCOLIPID CONCENTRATIONS IN CELLS TRANSFORMED BY A TEMPERATURE-SENSITIVE POLYOMA-VIRUS MUTANT, NATURE 248: 413 (1974). (10.1038/248413a0) / NATURE (1974)
GAHMBERG, C.G., ALTERED GROWTH-BEHAVIOR OF MALIGNANT CELLS ASSOCIATED WITH CHANGES IN EXTERNALLY LABELED GLYCOPROTEIN AND GLYCOLIPID, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70: 3329 (1973). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1973)
HAYASHI, I, REPLACEMENT OF SERUM BY HORMONES PERMITS GROWTH OF CELLS IN A DEFINED MEDIUM, NATURE 259: 132 (1976). (10.1038/259132a0) / NATURE (1976)
HOGG, N.M., COMPARISON OF MEMBRANE PROTEINS OF NORMAL AND TRANSFORMED-CELLS BY LACTOPEROXIDASE LABELING, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 71: 489 (1974). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1974)
HYNES, R.O., CELL-SURFACE PROTEINS AND MALIGNANT TRANSFORMATION, BIOCHIMICA ET BIOPHYSICA ACTA 458: 73 (1976). / BIOCHIMICA ET BIOPHYSICA ACTA (1976)
HYNES, R.O., DENSITY AND CELL-CYCLE DEPENDENCE OF CELL-SURFACE PROTEINS IN HAMSTER FIBROBLASTS, CELL 3: 113 (1974). (10.1016/0092-8674(74)90114-7) / CELL (1974)
10.1073/pnas.70.11.3170
MOSESSON, M.W., COLD-INSOLUBLE GLOBULIN OF HUMAN PLASMA .1. PURIFICATION, PRIMARY CHARACTERIZATION, AND RELATIONSHIP TO FIBRINOGEN AND OTHER COLD-INSOLUBLE FRACTION COMPONENTS, JOURNAL OF BIOLOGICAL CHEMISTRY 245: 5728 (1970). (10.1016/S0021-9258(18)62713-9) / JOURNAL OF BIOLOGICAL CHEMISTRY (1970)
PAUL, D, SERUM FACTOR REQUIREMENTS OF NORMAL AND SIMIAN VIRUS 40-TRANSFORMED 3T3 MOUSE FIBROBLASTS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 68: 645 (1971). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1971)
PEARLSTEIN, E, METABOLIC STUDIES ON I-125-LABELED BABY HAMSTER KIDNEY-CELL PLASMA-MEMBRANES, BIOCHIMICA ET BIOPHYSICA ACTA 362: 1 (1974). (10.1016/0304-4165(74)90019-1) / BIOCHIMICA ET BIOPHYSICA ACTA (1974)
PINDYCK, J, STEROID EFFECTS ON FIBRINOGEN SYNTHESIS BY CULTURED EMBRYONIC CHICKEN HEPATOCYTES, BIOCHEMICAL MEDICINE 12: 22 (1975). (10.1016/0006-2944(75)90092-7) / BIOCHEMICAL MEDICINE (1975)
TAYLOR, J.M., EPIDERMAL GROWTH-FACTOR - PHYSICAL AND CHEMICAL PROPERTIES, JOURNAL OF BIOLOGICAL CHEMISTRY 247: 5928 (1972). (10.1016/S0021-9258(19)44847-3) / JOURNAL OF BIOLOGICAL CHEMISTRY (1972)
Vaheri, A., Virus-Transformed Cell Membrane: 1 (1978). / Virus-Transformed Cell Membrane (1978)
WARTIOVAARA, J, DISTRIBUTION OF FIBROBLAST SURFACE ANTIGEN - ASSOCIATION WITH FIBRILLAR STRUCTURES OF NORMAL CELLS AND LOSS UPON VIRAL TRANSFORMATION, JOURNAL OF EXPERIMENTAL MEDICINE 140: 1522 (1974). (10.1084/jem.140.6.1522) / JOURNAL OF EXPERIMENTAL MEDICINE (1974)
Wickus, G. G., Control of Proliferation in Animal Cells: 541 (1974). / Control of Proliferation in Animal Cells (1974)
YAMADA, K.M., MAJOR CELL-SURFACE GLYCOPROTEIN OF CHICK-EMBRYO FIBROBLASTS IS AN AGGLUTININ, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 72: 3158 (1975). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1975)
YAMADA, K.M., CELL-SURFACE PROTEIN PARTIALLY RESTORES MORPHOLOGY, ADHESIVENESS, AND CONTACT INHIBITION OF MOVEMENT TO TRANSFORMED FIBROBLASTS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73: 1217 (1976). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1976)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 12:03 p.m.)
Deposited	1 year, 7 months ago (Jan. 13, 2024, 9:54 a.m.)
Indexed	1 year, 2 months ago (June 17, 2024, 4:30 p.m.)
Issued	48 years ago (Aug. 19, 1977)
Published	48 years ago (Aug. 19, 1977)
Published Print	48 years ago (Aug. 19, 1977)

Funders 0

None

BibTeX

@article{Chen_1977, title={Control of a Cell Surface Major Glycoprotein by Epidermal Growth Factor}, volume={197}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.302030}, DOI={10.1126/science.302030}, number={4305}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Chen, Lan Bo and Gudor, Robert C. and Sun, Tung-Tien and Chen, Anthony B. and Mosesson, Michael W.}, year={1977}, month=aug, pages={776–778} }

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