Discrete Start Sites for DNA Synthesis in the YeastARS1Origin
10.1126/science.279.5347.95
Crossref journal-article
American Association for the Advancement of Science (AAAS)
Science (221)
Abstract

Sites of DNA synthesis initiation have been detected at the nucleotide level in a yeast origin of bidirectional replication with the use of replication initiation point mapping. TheARS1origin ofSaccharomyces cerevisiaeshowed a transition from discontinuous to continuous DNA synthesis in an 18–base pair region (nucleotides 828 to 845) from within element B1 toward B2, adjacent to the binding site for the origin recognition complex, the putative initiator protein.

Bibliography

Bielinsky, A.-K., & Gerbi, S. A. (1998). Discrete Start Sites for DNA Synthesis in the YeastARS1Origin. Science, 279(5347), 95–98.

Authors 2
  1. Anja-Katrin Bielinsky (first)
  2. Susan A. Gerbi (additional)
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Dates
Type When
Created 23 years, 1 month ago (July 27, 2002, 5:42 a.m.)
Deposited 8 months, 2 weeks ago (Dec. 8, 2024, 1:14 p.m.)
Indexed 3 weeks ago (Aug. 7, 2025, 4:52 a.m.)
Issued 27 years, 7 months ago (Jan. 2, 1998)
Published 27 years, 7 months ago (Jan. 2, 1998)
Published Print 27 years, 7 months ago (Jan. 2, 1998)
Funders 0

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@article{Bielinsky_1998, title={Discrete Start Sites for DNA Synthesis in the YeastARS1Origin}, volume={279}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.279.5347.95}, DOI={10.1126/science.279.5347.95}, number={5347}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Bielinsky, Anja-Katrin and Gerbi, Susan A.}, year={1998}, month=jan, pages={95–98} }