DOI: 10.1126/science.276.5313.726. Signaling in Plant-Microbe Interactions

10.1126/science.276.5313.726

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Analysis of viral and bacterial pathogenesis has revealed common themes in the ways in which plants and animals respond to pathogenic agents. Pathogenic bacteria use macromolecule delivery systems (types III and IV) to deliver microbial avirulence proteins and transfer DNA-protein complexes directly into plant cells. The molecular events that constitute critical steps of plant-pathogen interactions seem to involve ligand-receptor mechanisms for pathogen recognition and the induction of signal transduction pathways in the plant that lead to defense responses. Unraveling the molecular basis of disease resistance pathways has laid a foundation for the rational design of crop protection strategies.

Bibliography

Baker, B., Zambryski, P., Staskawicz, B., & Dinesh-Kumar, S. P. (1997). Signaling in Plant-Microbe Interactions. Science, 276(5313), 726â733.

Authors 4

Barbara Baker (first)
Patricia Zambryski (additional)
Brian Staskawicz (additional)
S. P. Dinesh-Kumar (additional)

References 134 Referenced 701

Long S. R., Plant Cell 8, 1885 (1996). / Plant Cell by Long S. R. (1996)
K. Pawlowski and T. Bisseling ibid. p. 1899.
Dixon R. A., et al., Annu. Rev. Phytopathol. 32, 479 (1994). (10.1146/annurev.py.32.090194.002403) / Annu. Rev. Phytopathol. by Dixon R. A. (1994)
Ryals J. A., et al., Plant Cell 8, 1809 (1996). (10.2307/3870231) / Plant Cell by Ryals J. A. (1996)
10.1146/annurev.py.09.090171.001423
Gabriel D. W., Rolfe B. G., ibid. 28, 365 (1990). / ibid. by Gabriel D. W. (1990)
Jones J. D. G., Nature 385, 397 (1997). (10.1038/385397a0) / Nature by Jones J. D. G. (1997)
Meyerowitz E. M., Cell 56, 263 (1989). (10.1016/0092-8674(89)90900-8) / Cell by Meyerowitz E. M. (1989)
J. L. Dangl Adv. Plant Pathol. 10 127 (1993).
I. Crute et al. in Arabidopsis E. M. Meyerowitz and C. R. Somerville Eds. (Cold Spring Harbor Laboratory Press Cold Spring Harbor NY 1994) pp. 705–747.
Kunkel B. N., Trends Genet. 12, 63 (1996). (10.1016/0168-9525(96)81402-8) / Trends Genet. by Kunkel B. N. (1996)
M. A. Botella et al. in preparation.
Whalen M. C., Innes R. W., Bent A. F., Staskawicz B. J., Plant Cell 3, 49 (1991). / Plant Cell by Whalen M. C. (1991)
Dangl J. L., et al., ibid. 4, 1359 (1992). / ibid. by Dangl J. L. (1992)
Innes R. W., et al., Plant J. 4, 813 (1993). (10.1046/j.1365-313X.1993.04050813.x) / Plant J. by Innes R. W. (1993)
Rahme L. G., et al., Science 268, 1899 (1995). (10.1126/science.7604262) / Science by Rahme L. G. (1995)
Cao H., Glazebrook J., Clarke J. D., Volko S., Dong X., Cell 88, 57 (1997). (10.1016/S0092-8674(00)81858-9) / Cell by Cao H. (1997)
R. A. Dietrich M. H. Richberg R. Schmidt C. Dean J. L. Dangl ibid. p. 685.
NPR1(17) LSD1(18) NDR1 (B. Staskawicz and K. Century personal communication) and EDS1 (A. Falk B. Feys J. Parker personal communication).
Barinaga M., Science 272, 1261 (1996). (10.1126/science.272.5266.1261) / Science by Barinaga M. (1996)
Gopalan S., et al., Plant Cell 8, 1095 (1996). / Plant Cell by Gopalan S. (1996)
10.1002/j.1460-2075.1994.tb06341.x
Lindgren P. B., Peet R. C., Panapoulos N. J., J. Bacteriol. 168, 512 (1986). (10.1128/jb.168.2.512-522.1986) / J. Bacteriol. by Lindgren P. B. (1986)
J. L. Dangl in Bacterial Pathogenesis of Plants and Animals: Molecular and Cellular Mechanisms J. L. Dangl Ed. (Springer-Verlag Heidelberg Germany 1994) vol. 192 pp. 99–118. (10.1007/978-3-642-78624-2_5)
Huang H.-C., et al., J. Bacteriol. 170, 4748 (1988). (10.1128/jb.170.10.4748-4756.1988) / J. Bacteriol. by Huang H.-C. (1988)
S. V. Beer et al. in Advances in Molecular Genetics of Plant-Microbe Interactions H. Hennecke and D. P. S. Verma Eds. (Kluwer Academic Dordrecht Netherlands 1991) vol. 1 pp. 53–60.
Salmond G. P. C., Annu. Rev. Phytopathol. 32, 181 (1994). (10.1146/annurev.py.32.090194.001145) / Annu. Rev. Phytopathol. by Salmond G. P. C. (1994)
Michiels T., Cornelis G. R., J. Bacteriol. 173, 1677 (1991). (10.1128/jb.173.5.1677-1685.1991) / J. Bacteriol. by Michiels T. (1991)
Sory M. P., Cornelis G. R., Mol. Microbiol. 14, 583 (1994). (10.1111/j.1365-2958.1994.tb02191.x) / Mol. Microbiol. by Sory M. P. (1994)
Persson C., et al., ibid. 18, 135 (1995). / ibid. by Persson C. (1995)
Watarai M., Tobe T., Yoshikawa M., Sasakawa C., EMBO J. 14, 2461 (1995). (10.1002/j.1460-2075.1995.tb07243.x) / EMBO J. by Watarai M. (1995)
Zambryski P. C., Annu. Rev. Plant Physiol. Plant Mol. Biol. 43, 465 (1992). (10.1146/annurev.pp.43.060192.002341) / Annu. Rev. Plant Physiol. Plant Mol. Biol. by Zambryski P. C. (1992)
Lessl M., Lanka E., Cell 77, 321 (1994). (10.1016/0092-8674(94)90146-5) / Cell by Lessl M. (1994)
10.1126/science.273.5278.1107
Baron C., Zambryski P. C., Curr. Biol. 6, 1567 (1996). (10.1016/S0960-9822(02)70773-2) / Curr. Biol. by Baron C. (1996)
B. G. McLean F. D. Hempel P. C. Zambryski Plant Cell in press.
Carrington J. C., Kasschau K. D., Mahajan S. K., Schaad M. C., ibid. 8, 1669 (1996). / ibid. by Carrington J. C. (1996)
Ghoshroy S., Lartey R., Sheng J., Citovsky V., Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 27 (1997). (10.1146/annurev.arplant.48.1.27) / Annu. Rev. Plant Physiol. Plant Mol. Biol. by Ghoshroy S. (1997)
10.2307/3869694
10.1016/0092-8674(94)90366-2
Waigmann E., Lucas W. J., Citovsky V., Zambryski P., Proc. Natl. Acad. Sci. U.S.A. 91, 1433 (1994). (10.1073/pnas.91.4.1433) / Proc. Natl. Acad. Sci. U.S.A. by Waigmann E. (1994)
10.1006/viro.1995.1093
Citovsky V., Zambryski P., BioEssays 13, 373 (1991). (10.1002/bies.950130802) / BioEssays by Citovsky V. (1991)
Citovsky V., Wong M. L., Shaw A. L., Venkataram Prasad B. V., Zambryski P. C., Plant Cell 4, 397 (1992). / Plant Cell by Citovsky V. (1992)
10.1126/science.270.5244.1983
McLean B. G., Zupan J., Zambryski P. C., Plant Cell 7, 2101 (1995). / Plant Cell by McLean B. G. (1995)
Murillo I., Cavallarin L., San Segundo B., ibid. 9, 145 (1997). / ibid. by Murillo I. (1997)
Schaller A., Ryan C. A., BioEssays 18, 27 (1996). (10.1002/bies.950180108) / BioEssays by Schaller A. (1996)
Dangl J. L., Cell 80, 363 (1995). (10.1016/0092-8674(95)90485-9) / Cell by Dangl J. L. (1995)
10.1126/science.7732374
Bent A. F., et al., ibid. 265, 1856 (1994). / ibid. by Bent A. F. (1994)
Mindrinos M., Katagiri F., Yu G.-L., Ausubel F. M., Cell 78, 1089 (1994). (10.1016/0092-8674(94)90282-8) / Cell by Mindrinos M. (1994)
10.1126/science.7638602
Salmeron J. M., et al., Cell 86, 123 (1996). (10.1016/S0092-8674(00)80083-5) / Cell by Salmeron J. M. (1996)
Whitham S., et al., ibid. 78, 1101 (1994). / ibid. by Whitham S. (1994)
Lawrence G. J., Finnegan E. J., Ayliffe M. A., Ellis J. G., Plant Cell 7, 1195 (1995). / Plant Cell by Lawrence G. J. (1995)
P. A. Anderson et al. ibid. in press.
J. E. Parker et al. ibid. in press.
N. Ori et al. ibid. in press.
10.1016/0092-8674(88)90516-8
Sims J. E., et al., Proc. Natl. Acad. Sci. U.S.A. 86, 8946 (1989). (10.1073/pnas.86.22.8946) / Proc. Natl. Acad. Sci. U.S.A. by Sims J. E. (1989)
10.1126/science.7902614
10.1016/S0092-8674(00)81290-8
10.1126/science.7973631
Cai D., et al., ibid. 275, 832 (1997). / ibid. by Cai D. (1997)
W.-Y. Song et al. ibid. 270 1804 (1995).
G. S. Johal and S. P. Briggs ibid. 258 985 (1992). (10.1126/science.1359642)
10.1016/0968-0004(94)90090-6
Padgett H. S., Beachy R. N., Plant Cell 5, 577 (1993). / Plant Cell by Padgett H. S. (1993)
Van den Ackerveken G., Marois E., Bonas U., Cell 87, 1307 (1996). (10.1016/S0092-8674(00)81825-5) / Cell by Van den Ackerveken G. (1996)
10.1126/science.274.5295.2063
X. Tang et al. ibid. p. 2060.
Leister R. T., Ausubel F. M., Katagiri F., Proc. Natl. Acad. Sci. U.S.A. 93, 15497 (1996). (10.1073/pnas.93.26.15497) / Proc. Natl. Acad. Sci. U.S.A. by Leister R. T. (1996)
J. A. L. van Kan G. F. J. M. van den Ackerveken P. J. G. M. de Wit Mol. Plant-Microbe Interact. 4 52 (1991).
Martin G. B., et al., Plant Cell 6, 1543 (1995). / Plant Cell by Martin G. B. (1995)
Rommens C. M. T., Salmeron J. M., Baulcombe D. C., Staskawicz B. J., ibid. 7, 249 (1995). / ibid. by Rommens C. M. T. (1995)
G.-L. Wang and P. C. Ronald personal communication.
J. G. Ellis G. J. Lawrence K. W. Shepherd unpublished data.
Kataoka T., Broek D., Wigler M., Cell 43, 493 (1985). (10.1016/0092-8674(85)90179-5) / Cell by Kataoka T. (1985)
S. P. Dinesh-Kumar and B. Baker unpublished data.
Saraste M., Sibbald P. R., Wittinghofer A., Trends Biochem. Sci. 15, 430 (1990). (10.1016/0968-0004(90)90281-F) / Trends Biochem. Sci. by Saraste M. (1990)
10.1038/349117a0
F. Katagiri and F. Ausubel personal communication.
Farnsworth C. L., Feig L. A., Mol. Cell. Biol. 11, 4822 (1991). / Mol. Cell. Biol. by Farnsworth C. L. (1991)
J. D. Hilderbrandt R. Day C. L. Farnsworth L. A. Feig ibid. p. 4830.
Levine A., Tenhaken R., Dixon R., Lamb C., Cell 79, 583 (1994). (10.1016/0092-8674(94)90544-4) / Cell by Levine A. (1994)
Levine A., Pennell R., Palmer R., Lamb C. J., Curr. Biol. 6, 427 (1996). (10.1016/S0960-9822(02)00510-9) / Curr. Biol. by Levine A. (1996)
10.1126/science.273.5283.1853
Tenhaken R., Levine A., Brisson L. F., Dixon R. A., Lamb C. J., Proc. Natl. Acad. Sci. U.S.A. 92, 4158 (1995). (10.1073/pnas.92.10.4158) / Proc. Natl. Acad. Sci. U.S.A. by Tenhaken R. (1995)
Dwyer S. C., Legendre L., Low P. S., Leto T. L., Biochim. Biophys. Acta 1289, 231 (1995). (10.1016/0304-4165(95)00156-5) / Biochim. Biophys. Acta by Dwyer S. C. (1995)
Groom Q. J., et al., Plant J. 10, 515 (1996). (10.1046/j.1365-313X.1996.10030515.x) / Plant J. by Groom Q. J. (1996)
Dangl J. L., Dietrich R. A., Richberg M. H., Plant Cell 8, 1793 (1996). (10.2307/3870230) / Plant Cell by Dangl J. L. (1996)
10.1016/0092-8674(94)90218-6
J. T. Greenberg A. Guo D. F. Klessig F. M. Ausubel ibid. p. 551.
Hu G., Richter T. E., Hulbert S. H., Pryor T., Plant Cell 8, 1367 (1996). (10.2307/3870307) / Plant Cell by Hu G. (1996)
Buschges R., et al., Cell 88, 695 (1997). (10.1016/S0092-8674(00)81912-1) / Cell by Buschges R. (1997)
10.1126/science.250.4983.1002
Delaney T. P., et al., ibid. 266, 1247 (1994). / ibid. by Delaney T. P. (1994)
Vernooij B., et al., Plant Cell 6, 959 (1994). (10.2307/3870006) / Plant Cell by Vernooij B. (1994)
Shulaev V., Leon J., Raskin I., ibid. 7, 1691 (1995). / ibid. by Shulaev V. (1995)
S. A. Bowling et al. ibid. 6 1845 (1994). (10.2307/3869912)
H. Cao S. A. Bowling A. S. Gordon X. Dong ibid. p. 1583.
Delaney T., Friedrich L., Ryals J., Proc. Natl. Acad. Sci. U.S.A. 92, 6602 (1995). (10.1073/pnas.92.14.6602) / Proc. Natl. Acad. Sci. U.S.A. by Delaney T. (1995)
K. S. Century E. B. Holub B. J. Staskawicz ibid. p. 6597.
Parker J. E., et al., Plant Cell 8, 2033 (1996). / Plant Cell by Parker J. E. (1996)
Freialdenhoven A., et al., ibid. 6, 983 (1994). / ibid. by Freialdenhoven A. (1994)
K. E. Hammond-Kosack D. A. Jones J. D. G. Jones ibid. p. 361.
Ausubel F. M., Katagiri F., Mindrinos M., Glazebrook J., Proc. Natl. Acad. Sci. U.S.A. 92, 4189 (1995). (10.1073/pnas.92.10.4189) / Proc. Natl. Acad. Sci. U.S.A. by Ausubel F. M. (1995)
Glazebrook J., Ausubel F. M., ibid. 91, 8955 (1994). / ibid. by Glazebrook J. (1994)
T. J. Pryor and J. Ellis Adv. Plant Pathol. 10 281 (1993).
W.-Y. Song and P. C. Ronald in preparation.
Richter T. E., Pryor T. J., Bennetzen J. L., Hulbert S. H., Genetics 141, 373 (1995). (10.1093/genetics/141.1.373) / Genetics by Richter T. E. (1995)
S. Whitham and B. Baker unpublished data.
Morisato D., Anderson K. V., Annu. Rev. Genet. 29, 371 (1995). (10.1146/annurev.ge.29.120195.002103) / Annu. Rev. Genet. by Morisato D. (1995)
10.1101/gad.9.22.2723
10.1126/science.271.5252.1128
Shelton C. A., Wasserman S. A., Cell 72, 515 (1993). (10.1016/0092-8674(93)90071-W) / Cell by Shelton C. A. (1993)
Ip Y. T., et al., ibid. 75, 753 (1993). / ibid. by Ip Y. T. (1993)
B. Lamaitre E. Nicolas L. Michaut J.-M. Reichhart J. A. Hoffmann ibid. 86 973 (1996). (10.1016/S0092-8674(00)80172-5)
Dinesh-Kumar S. P., et al., Proc. Natl. Acad. Sci. U.S.A. 92, 4175 (1995). (10.1073/pnas.92.10.4175) / Proc. Natl. Acad. Sci. U.S.A. by Dinesh-Kumar S. P. (1995)
S. E. Clark R. W. Williams E. M. Meyerowitz unpublished data.
Torii K. U., et al., Plant Cell 8, 735 (1996). / Plant Cell by Torii K. U. (1996)
Schreck R., Baeuerle P. A., Trends Cell Biol. 1, 39 (1991). (10.1016/0962-8924(91)90072-H) / Trends Cell Biol. by Schreck R. (1991)
Meyer M., Schreck R., Baeuerle P. A., EMBO J. 12, 2005 (1993). (10.1002/j.1460-2075.1993.tb05850.x) / EMBO J. by Meyer M. (1993)
10.1126/science.8052854
Van Gijsegem F., Genin S., Boucher C., Trends Microbiol. 1, 175 (1993). (10.1016/0966-842X(93)90087-8) / Trends Microbiol. by Van Gijsegem F. (1993)
H.-C. Huang R.-W. Lin C.-J. Chang A. Collmer W.-L. Deng Mol. Plant-Microbe Interact. 8 733 (1995).
Bogdanove A. J., et al., Mol. Microbiol. 20, 681 (1996). (10.1046/j.1365-2958.1996.5731077.x) / Mol. Microbiol. by Bogdanove A. J. (1996)
E. C. Oerke H. W. Dehne F. Schonbeck A. Weber Crop Production and Crop Protection. Estimated Losses in Major Food and Cash Crops (Elsevier New York 1994).
Alber T., Curr. Opin. Genet. Dev. 2, 205 (1992). (10.1016/S0959-437X(05)80275-8) / Curr. Opin. Genet. Dev. by Alber T. (1992)
Traut T. W., Eur. J. Biochem. 222, 9 (1994). (10.1111/j.1432-1033.1994.tb18835.x) / Eur. J. Biochem. by Traut T. W. (1994)
Gay N. J., Keith F. J., Nature 351, 355 (1991). (10.1038/351355b0) / Nature by Gay N. J. (1991)
Kyte J., Doolittle R. F., J. Mol. Biol. 157, 105 (1982). (10.1016/0022-2836(82)90515-0) / J. Mol. Biol. by Kyte J. (1982)
B.B. is supported by U.S. Department of Agriculture grants CRIS 5335-22000-004-00D and NRICGP 5335-22000-004-03T P.Z. is supported by NIH grant GM45244 and NSF grant IBN9507782 and B.J.S. is supported by U.S. Department of Energy (DOE) grant DE-FG03-88ER13917 and NSF grant MCB-9219959. S.P.D.-K. is a Life Science Research Foundation postdoctoral fellow sponsored by DOE. We thank A. Boughton for excellent artwork; S. Sommerville P. Ronald R. Howard B. Jaffer and V. Williamson for discussion and scanning electron micrographs of pathogens; the many colleagues who provided preprints unpublished results and critical comments for this review; and C. Tobias for help in preparation of the Hrp secretion figure.

Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 5:45 a.m.)
Deposited	1 year, 7 months ago (Jan. 13, 2024, 1 a.m.)
Indexed	2 weeks, 5 days ago (Aug. 7, 2025, 4:43 p.m.)
Issued	28 years, 3 months ago (May 2, 1997)
Published	28 years, 3 months ago (May 2, 1997)
Published Print	28 years, 3 months ago (May 2, 1997)

Funders 0

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BibTeX

@article{Baker_1997, title={Signaling in Plant-Microbe Interactions}, volume={276}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.276.5313.726}, DOI={10.1126/science.276.5313.726}, number={5313}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Baker, Barbara and Zambryski, Patricia and Staskawicz, Brian and Dinesh-Kumar, S. P.}, year={1997}, month=may, pages={726–733} }

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  "abstract": "<jats:p>Analysis of viral and bacterial pathogenesis has revealed common themes in the ways in which plants and animals respond to pathogenic agents. Pathogenic bacteria use macromolecule delivery systems (types III and IV) to deliver microbial avirulence proteins and transfer DNA-protein complexes directly into plant cells. The molecular events that constitute critical steps of plant-pathogen interactions seem to involve ligand-receptor mechanisms for pathogen recognition and the induction of signal transduction pathways in the plant that lead to defense responses. Unraveling the molecular basis of disease resistance pathways has laid a foundation for the rational design of crop protection strategies.</jats:p>",
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      "key": "e_1_3_1_2_2",
      "first-page": "1885",
      "volume": "8",
      "author": "Long S. R.",
      "year": "1996",
      "unstructured": "Long S. R., Plant Cell 8, 1885 (1996).",
      "journal-title": "Plant Cell"
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      "unstructured": "K. Pawlowski and T. Bisseling ibid. p. 1899."
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      "first-page": "479",
      "DOI": "10.1146/annurev.py.32.090194.002403",
      "volume": "32",
      "author": "Dixon R. A.",
      "year": "1994",
      "unstructured": "Dixon R. A., et al., Annu. Rev. Phytopathol. 32, 479 (1994).",
      "journal-title": "Annu. Rev. Phytopathol."
    },
    {
      "key": "e_1_3_1_5_2",
      "doi-asserted-by": "crossref",
      "first-page": "1809",
      "DOI": "10.2307/3870231",
      "volume": "8",
      "author": "Ryals J. A.",
      "year": "1996",
      "unstructured": "Ryals J. A., et al., Plant Cell 8, 1809 (1996).",
      "journal-title": "Plant Cell"
    },
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    {
      "key": "e_1_3_1_7_2",
      "first-page": "365",
      "volume": "28",
      "author": "Gabriel D. W.",
      "year": "1990",
      "unstructured": "Gabriel D. W., Rolfe B. G., ibid. 28, 365 (1990).",
      "journal-title": "ibid."
    },
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      "key": "e_1_3_1_8_2",
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      "first-page": "397",
      "DOI": "10.1038/385397a0",
      "volume": "385",
      "author": "Jones J. D. G.",
      "year": "1997",
      "unstructured": "Jones J. D. G., Nature 385, 397 (1997).",
      "journal-title": "Nature"
    },
    {
      "key": "e_1_3_1_9_2",
      "doi-asserted-by": "crossref",
      "first-page": "263",
      "DOI": "10.1016/0092-8674(89)90900-8",
      "volume": "56",
      "author": "Meyerowitz E. M.",
      "year": "1989",
      "unstructured": "Meyerowitz E. M., Cell 56, 263 (1989).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_10_2",
      "unstructured": "J. L. Dangl Adv. Plant Pathol. 10 127 (1993)."
    },
    {
      "key": "e_1_3_1_11_2",
      "unstructured": "I. Crute et al. in Arabidopsis E. M. Meyerowitz and C. R. Somerville Eds. (Cold Spring Harbor Laboratory Press Cold Spring Harbor NY 1994) pp. 705\u2013747."
    },
    {
      "key": "e_1_3_1_12_2",
      "doi-asserted-by": "crossref",
      "first-page": "63",
      "DOI": "10.1016/0168-9525(96)81402-8",
      "volume": "12",
      "author": "Kunkel B. N.",
      "year": "1996",
      "unstructured": "Kunkel B. N., Trends Genet. 12, 63 (1996).",
      "journal-title": "Trends Genet."
    },
    {
      "key": "e_1_3_1_13_2",
      "unstructured": "M. A. Botella et al. in preparation."
    },
    {
      "key": "e_1_3_1_14_2",
      "first-page": "49",
      "volume": "3",
      "author": "Whalen M. C.",
      "year": "1991",
      "unstructured": "Whalen M. C., Innes R. W., Bent A. F., Staskawicz B. J., Plant Cell 3, 49 (1991).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_15_2",
      "first-page": "1359",
      "volume": "4",
      "author": "Dangl J. L.",
      "year": "1992",
      "unstructured": "Dangl J. L., et al., ibid. 4, 1359 (1992).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_16_2",
      "doi-asserted-by": "crossref",
      "first-page": "813",
      "DOI": "10.1046/j.1365-313X.1993.04050813.x",
      "volume": "4",
      "author": "Innes R. W.",
      "year": "1993",
      "unstructured": "Innes R. W., et al., Plant J. 4, 813 (1993).",
      "journal-title": "Plant J."
    },
    {
      "key": "e_1_3_1_17_2",
      "doi-asserted-by": "crossref",
      "first-page": "1899",
      "DOI": "10.1126/science.7604262",
      "volume": "268",
      "author": "Rahme L. G.",
      "year": "1995",
      "unstructured": "Rahme L. G., et al., Science 268, 1899 (1995).",
      "journal-title": "Science"
    },
    {
      "key": "e_1_3_1_18_2",
      "doi-asserted-by": "crossref",
      "first-page": "57",
      "DOI": "10.1016/S0092-8674(00)81858-9",
      "volume": "88",
      "author": "Cao H.",
      "year": "1997",
      "unstructured": "Cao H., Glazebrook J., Clarke J. D., Volko S., Dong X., Cell 88, 57 (1997).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_19_2",
      "unstructured": "R. A. Dietrich M. H. Richberg R. Schmidt C. Dean J. L. Dangl ibid. p. 685."
    },
    {
      "key": "e_1_3_1_20_2",
      "unstructured": "NPR1(17) LSD1(18) NDR1 (B. Staskawicz and K. Century personal communication) and EDS1 (A. Falk B. Feys J. Parker personal communication)."
    },
    {
      "key": "e_1_3_1_21_2",
      "doi-asserted-by": "crossref",
      "first-page": "1261",
      "DOI": "10.1126/science.272.5266.1261",
      "volume": "272",
      "author": "Barinaga M.",
      "year": "1996",
      "unstructured": "Barinaga M., Science 272, 1261 (1996).",
      "journal-title": "Science"
    },
    {
      "key": "e_1_3_1_22_2",
      "first-page": "1095",
      "volume": "8",
      "author": "Gopalan S.",
      "year": "1996",
      "unstructured": "Gopalan S., et al., Plant Cell 8, 1095 (1996).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_23_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/j.1460-2075.1994.tb06341.x"
    },
    {
      "key": "e_1_3_1_24_2",
      "doi-asserted-by": "crossref",
      "first-page": "512",
      "DOI": "10.1128/jb.168.2.512-522.1986",
      "volume": "168",
      "author": "Lindgren P. B.",
      "year": "1986",
      "unstructured": "Lindgren P. B., Peet R. C., Panapoulos N. J., J. Bacteriol. 168, 512 (1986).",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_3_1_25_2",
      "doi-asserted-by": "crossref",
      "unstructured": "J. L. Dangl in Bacterial Pathogenesis of Plants and Animals: Molecular and Cellular Mechanisms J. L. Dangl Ed. (Springer-Verlag Heidelberg Germany 1994) vol. 192 pp. 99\u2013118.",
      "DOI": "10.1007/978-3-642-78624-2_5"
    },
    {
      "key": "e_1_3_1_26_2",
      "doi-asserted-by": "crossref",
      "first-page": "4748",
      "DOI": "10.1128/jb.170.10.4748-4756.1988",
      "volume": "170",
      "author": "Huang H.-C.",
      "year": "1988",
      "unstructured": "Huang H.-C., et al., J. Bacteriol. 170, 4748 (1988).",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_3_1_27_2",
      "unstructured": "S. V. Beer et al. in Advances in Molecular Genetics of Plant-Microbe Interactions H. Hennecke and D. P. S. Verma Eds. (Kluwer Academic Dordrecht Netherlands 1991) vol. 1 pp. 53\u201360."
    },
    {
      "key": "e_1_3_1_28_2",
      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1146/annurev.py.32.090194.001145",
      "volume": "32",
      "author": "Salmond G. P. C.",
      "year": "1994",
      "unstructured": "Salmond G. P. C., Annu. Rev. Phytopathol. 32, 181 (1994).",
      "journal-title": "Annu. Rev. Phytopathol."
    },
    {
      "key": "e_1_3_1_29_2",
      "doi-asserted-by": "crossref",
      "first-page": "1677",
      "DOI": "10.1128/jb.173.5.1677-1685.1991",
      "volume": "173",
      "author": "Michiels T.",
      "year": "1991",
      "unstructured": "Michiels T., Cornelis G. R., J. Bacteriol. 173, 1677 (1991).",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "e_1_3_1_30_2",
      "doi-asserted-by": "crossref",
      "first-page": "583",
      "DOI": "10.1111/j.1365-2958.1994.tb02191.x",
      "volume": "14",
      "author": "Sory M. P.",
      "year": "1994",
      "unstructured": "Sory M. P., Cornelis G. R., Mol. Microbiol. 14, 583 (1994).",
      "journal-title": "Mol. Microbiol."
    },
    {
      "key": "e_1_3_1_31_2",
      "first-page": "135",
      "volume": "18",
      "author": "Persson C.",
      "year": "1995",
      "unstructured": "Persson C., et al., ibid. 18, 135 (1995).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_32_2",
      "doi-asserted-by": "crossref",
      "first-page": "2461",
      "DOI": "10.1002/j.1460-2075.1995.tb07243.x",
      "volume": "14",
      "author": "Watarai M.",
      "year": "1995",
      "unstructured": "Watarai M., Tobe T., Yoshikawa M., Sasakawa C., EMBO J. 14, 2461 (1995).",
      "journal-title": "EMBO J."
    },
    {
      "key": "e_1_3_1_33_2",
      "doi-asserted-by": "crossref",
      "first-page": "465",
      "DOI": "10.1146/annurev.pp.43.060192.002341",
      "volume": "43",
      "author": "Zambryski P. C.",
      "year": "1992",
      "unstructured": "Zambryski P. C., Annu. Rev. Plant Physiol. Plant Mol. Biol. 43, 465 (1992).",
      "journal-title": "Annu. Rev. Plant Physiol. Plant Mol. Biol."
    },
    {
      "key": "e_1_3_1_34_2",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1016/0092-8674(94)90146-5",
      "volume": "77",
      "author": "Lessl M.",
      "year": "1994",
      "unstructured": "Lessl M., Lanka E., Cell 77, 321 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_35_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.273.5278.1107"
    },
    {
      "key": "e_1_3_1_36_2",
      "doi-asserted-by": "crossref",
      "first-page": "1567",
      "DOI": "10.1016/S0960-9822(02)70773-2",
      "volume": "6",
      "author": "Baron C.",
      "year": "1996",
      "unstructured": "Baron C., Zambryski P. C., Curr. Biol. 6, 1567 (1996).",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "e_1_3_1_37_2",
      "unstructured": "B. G. McLean F. D. Hempel P. C. Zambryski Plant Cell in press."
    },
    {
      "key": "e_1_3_1_38_2",
      "first-page": "1669",
      "volume": "8",
      "author": "Carrington J. C.",
      "year": "1996",
      "unstructured": "Carrington J. C., Kasschau K. D., Mahajan S. K., Schaad M. C., ibid. 8, 1669 (1996).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_39_2",
      "doi-asserted-by": "crossref",
      "first-page": "27",
      "DOI": "10.1146/annurev.arplant.48.1.27",
      "volume": "48",
      "author": "Ghoshroy S.",
      "year": "1997",
      "unstructured": "Ghoshroy S., Lartey R., Sheng J., Citovsky V., Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 27 (1997).",
      "journal-title": "Annu. Rev. Plant Physiol. Plant Mol. Biol."
    },
    {
      "key": "e_1_3_1_40_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.2307/3869694"
    },
    {
      "key": "e_1_3_1_41_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(94)90366-2"
    },
    {
      "key": "e_1_3_1_42_2",
      "doi-asserted-by": "crossref",
      "first-page": "1433",
      "DOI": "10.1073/pnas.91.4.1433",
      "volume": "91",
      "author": "Waigmann E.",
      "year": "1994",
      "unstructured": "Waigmann E., Lucas W. J., Citovsky V., Zambryski P., Proc. Natl. Acad. Sci. U.S.A. 91, 1433 (1994).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_43_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1006/viro.1995.1093"
    },
    {
      "key": "e_1_3_1_44_2",
      "doi-asserted-by": "crossref",
      "first-page": "373",
      "DOI": "10.1002/bies.950130802",
      "volume": "13",
      "author": "Citovsky V.",
      "year": "1991",
      "unstructured": "Citovsky V., Zambryski P., BioEssays 13, 373 (1991).",
      "journal-title": "BioEssays"
    },
    {
      "key": "e_1_3_1_45_2",
      "first-page": "397",
      "volume": "4",
      "author": "Citovsky V.",
      "year": "1992",
      "unstructured": "Citovsky V., Wong M. L., Shaw A. L., Venkataram Prasad B. V., Zambryski P. C., Plant Cell 4, 397 (1992).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_46_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.270.5244.1983"
    },
    {
      "key": "e_1_3_1_47_2",
      "first-page": "2101",
      "volume": "7",
      "author": "McLean B. G.",
      "year": "1995",
      "unstructured": "McLean B. G., Zupan J., Zambryski P. C., Plant Cell 7, 2101 (1995).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_48_2",
      "first-page": "145",
      "volume": "9",
      "author": "Murillo I.",
      "year": "1997",
      "unstructured": "Murillo I., Cavallarin L., San Segundo B., ibid. 9, 145 (1997).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_49_2",
      "doi-asserted-by": "crossref",
      "first-page": "27",
      "DOI": "10.1002/bies.950180108",
      "volume": "18",
      "author": "Schaller A.",
      "year": "1996",
      "unstructured": "Schaller A., Ryan C. A., BioEssays 18, 27 (1996).",
      "journal-title": "BioEssays"
    },
    {
      "key": "e_1_3_1_50_2",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1016/0092-8674(95)90485-9",
      "volume": "80",
      "author": "Dangl J. L.",
      "year": "1995",
      "unstructured": "Dangl J. L., Cell 80, 363 (1995).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_51_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.7732374"
    },
    {
      "key": "e_1_3_1_52_2",
      "first-page": "1856",
      "volume": "265",
      "author": "Bent A. F.",
      "year": "1994",
      "unstructured": "Bent A. F., et al., ibid. 265, 1856 (1994).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_53_2",
      "doi-asserted-by": "crossref",
      "first-page": "1089",
      "DOI": "10.1016/0092-8674(94)90282-8",
      "volume": "78",
      "author": "Mindrinos M.",
      "year": "1994",
      "unstructured": "Mindrinos M., Katagiri F., Yu G.-L., Ausubel F. M., Cell 78, 1089 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_54_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.7638602"
    },
    {
      "key": "e_1_3_1_55_2",
      "doi-asserted-by": "crossref",
      "first-page": "123",
      "DOI": "10.1016/S0092-8674(00)80083-5",
      "volume": "86",
      "author": "Salmeron J. M.",
      "year": "1996",
      "unstructured": "Salmeron J. M., et al., Cell 86, 123 (1996).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_56_2",
      "first-page": "1101",
      "volume": "78",
      "author": "Whitham S.",
      "year": "1994",
      "unstructured": "Whitham S., et al., ibid. 78, 1101 (1994).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_57_2",
      "first-page": "1195",
      "volume": "7",
      "author": "Lawrence G. J.",
      "year": "1995",
      "unstructured": "Lawrence G. J., Finnegan E. J., Ayliffe M. A., Ellis J. G., Plant Cell 7, 1195 (1995).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_58_2",
      "unstructured": "P. A. Anderson et al. ibid. in press."
    },
    {
      "key": "e_1_3_1_59_2",
      "unstructured": "J. E. Parker et al. ibid. in press."
    },
    {
      "key": "e_1_3_1_60_2",
      "unstructured": "N. Ori et al. ibid. in press."
    },
    {
      "key": "e_1_3_1_61_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(88)90516-8"
    },
    {
      "key": "e_1_3_1_62_2",
      "doi-asserted-by": "crossref",
      "first-page": "8946",
      "DOI": "10.1073/pnas.86.22.8946",
      "volume": "86",
      "author": "Sims J. E.",
      "year": "1989",
      "unstructured": "Sims J. E., et al., Proc. Natl. Acad. Sci. U.S.A. 86, 8946 (1989).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_63_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.7902614"
    },
    {
      "key": "e_1_3_1_64_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0092-8674(00)81290-8"
    },
    {
      "key": "e_1_3_1_65_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.7973631"
    },
    {
      "key": "e_1_3_1_66_2",
      "first-page": "832",
      "volume": "275",
      "author": "Cai D.",
      "year": "1997",
      "unstructured": "Cai D., et al., ibid. 275, 832 (1997).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_67_2",
      "unstructured": "W.-Y. Song et al. ibid. 270 1804 (1995)."
    },
    {
      "key": "e_1_3_1_68_2",
      "doi-asserted-by": "crossref",
      "unstructured": "G. S. Johal and S. P. Briggs ibid. 258 985 (1992).",
      "DOI": "10.1126/science.1359642"
    },
    {
      "key": "e_1_3_1_69_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0968-0004(94)90090-6"
    },
    {
      "key": "e_1_3_1_70_2",
      "first-page": "577",
      "volume": "5",
      "author": "Padgett H. S.",
      "year": "1993",
      "unstructured": "Padgett H. S., Beachy R. N., Plant Cell 5, 577 (1993).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_71_2",
      "doi-asserted-by": "crossref",
      "first-page": "1307",
      "DOI": "10.1016/S0092-8674(00)81825-5",
      "volume": "87",
      "author": "Van den Ackerveken G.",
      "year": "1996",
      "unstructured": "Van den Ackerveken G., Marois E., Bonas U., Cell 87, 1307 (1996).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_72_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.274.5295.2063"
    },
    {
      "key": "e_1_3_1_73_2",
      "unstructured": "X. Tang et al. ibid. p. 2060."
    },
    {
      "key": "e_1_3_1_74_2",
      "doi-asserted-by": "crossref",
      "first-page": "15497",
      "DOI": "10.1073/pnas.93.26.15497",
      "volume": "93",
      "author": "Leister R. T.",
      "year": "1996",
      "unstructured": "Leister R. T., Ausubel F. M., Katagiri F., Proc. Natl. Acad. Sci. U.S.A. 93, 15497 (1996).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_75_2",
      "unstructured": "J. A. L. van Kan G. F. J. M. van den Ackerveken P. J. G. M. de Wit Mol. Plant-Microbe Interact. 4 52 (1991)."
    },
    {
      "key": "e_1_3_1_76_2",
      "first-page": "1543",
      "volume": "6",
      "author": "Martin G. B.",
      "year": "1995",
      "unstructured": "Martin G. B., et al., Plant Cell 6, 1543 (1995).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_77_2",
      "first-page": "249",
      "volume": "7",
      "author": "Rommens C. M. T.",
      "year": "1995",
      "unstructured": "Rommens C. M. T., Salmeron J. M., Baulcombe D. C., Staskawicz B. J., ibid. 7, 249 (1995).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_78_2",
      "unstructured": "G.-L. Wang and P. C. Ronald personal communication."
    },
    {
      "key": "e_1_3_1_79_2",
      "unstructured": "J. G. Ellis G. J. Lawrence K. W. Shepherd unpublished data."
    },
    {
      "key": "e_1_3_1_80_2",
      "doi-asserted-by": "crossref",
      "first-page": "493",
      "DOI": "10.1016/0092-8674(85)90179-5",
      "volume": "43",
      "author": "Kataoka T.",
      "year": "1985",
      "unstructured": "Kataoka T., Broek D., Wigler M., Cell 43, 493 (1985).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_81_2",
      "unstructured": "S. P. Dinesh-Kumar and B. Baker unpublished data."
    },
    {
      "key": "e_1_3_1_82_2",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1016/0968-0004(90)90281-F",
      "volume": "15",
      "author": "Saraste M.",
      "year": "1990",
      "unstructured": "Saraste M., Sibbald P. R., Wittinghofer A., Trends Biochem. Sci. 15, 430 (1990).",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "e_1_3_1_83_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/349117a0"
    },
    {
      "key": "e_1_3_1_84_2",
      "unstructured": "F. Katagiri and F. Ausubel personal communication."
    },
    {
      "key": "e_1_3_1_85_2",
      "first-page": "4822",
      "volume": "11",
      "author": "Farnsworth C. L.",
      "year": "1991",
      "unstructured": "Farnsworth C. L., Feig L. A., Mol. Cell. Biol. 11, 4822 (1991).",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "e_1_3_1_86_2",
      "unstructured": "J. D. Hilderbrandt R. Day C. L. Farnsworth L. A. Feig ibid. p. 4830."
    },
    {
      "key": "e_1_3_1_87_2",
      "doi-asserted-by": "crossref",
      "first-page": "583",
      "DOI": "10.1016/0092-8674(94)90544-4",
      "volume": "79",
      "author": "Levine A.",
      "year": "1994",
      "unstructured": "Levine A., Tenhaken R., Dixon R., Lamb C., Cell 79, 583 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_88_2",
      "doi-asserted-by": "crossref",
      "first-page": "427",
      "DOI": "10.1016/S0960-9822(02)00510-9",
      "volume": "6",
      "author": "Levine A.",
      "year": "1996",
      "unstructured": "Levine A., Pennell R., Palmer R., Lamb C. J., Curr. Biol. 6, 427 (1996).",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "e_1_3_1_89_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.273.5283.1853"
    },
    {
      "key": "e_1_3_1_90_2",
      "doi-asserted-by": "crossref",
      "first-page": "4158",
      "DOI": "10.1073/pnas.92.10.4158",
      "volume": "92",
      "author": "Tenhaken R.",
      "year": "1995",
      "unstructured": "Tenhaken R., Levine A., Brisson L. F., Dixon R. A., Lamb C. J., Proc. Natl. Acad. Sci. U.S.A. 92, 4158 (1995).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_91_2",
      "doi-asserted-by": "crossref",
      "first-page": "231",
      "DOI": "10.1016/0304-4165(95)00156-5",
      "volume": "1289",
      "author": "Dwyer S. C.",
      "year": "1995",
      "unstructured": "Dwyer S. C., Legendre L., Low P. S., Leto T. L., Biochim. Biophys. Acta 1289, 231 (1995).",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "e_1_3_1_92_2",
      "doi-asserted-by": "crossref",
      "first-page": "515",
      "DOI": "10.1046/j.1365-313X.1996.10030515.x",
      "volume": "10",
      "author": "Groom Q. J.",
      "year": "1996",
      "unstructured": "Groom Q. J., et al., Plant J. 10, 515 (1996).",
      "journal-title": "Plant J."
    },
    {
      "key": "e_1_3_1_93_2",
      "doi-asserted-by": "crossref",
      "first-page": "1793",
      "DOI": "10.2307/3870230",
      "volume": "8",
      "author": "Dangl J. L.",
      "year": "1996",
      "unstructured": "Dangl J. L., Dietrich R. A., Richberg M. H., Plant Cell 8, 1793 (1996).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_94_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(94)90218-6"
    },
    {
      "key": "e_1_3_1_95_2",
      "unstructured": "J. T. Greenberg A. Guo D. F. Klessig F. M. Ausubel ibid. p. 551."
    },
    {
      "key": "e_1_3_1_96_2",
      "doi-asserted-by": "crossref",
      "first-page": "1367",
      "DOI": "10.2307/3870307",
      "volume": "8",
      "author": "Hu G.",
      "year": "1996",
      "unstructured": "Hu G., Richter T. E., Hulbert S. H., Pryor T., Plant Cell 8, 1367 (1996).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_97_2",
      "doi-asserted-by": "crossref",
      "first-page": "695",
      "DOI": "10.1016/S0092-8674(00)81912-1",
      "volume": "88",
      "author": "Buschges R.",
      "year": "1997",
      "unstructured": "Buschges R., et al., Cell 88, 695 (1997).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_98_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.250.4983.1002"
    },
    {
      "key": "e_1_3_1_99_2",
      "first-page": "1247",
      "volume": "266",
      "author": "Delaney T. P.",
      "year": "1994",
      "unstructured": "Delaney T. P., et al., ibid. 266, 1247 (1994).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_100_2",
      "doi-asserted-by": "crossref",
      "first-page": "959",
      "DOI": "10.2307/3870006",
      "volume": "6",
      "author": "Vernooij B.",
      "year": "1994",
      "unstructured": "Vernooij B., et al., Plant Cell 6, 959 (1994).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_101_2",
      "first-page": "1691",
      "volume": "7",
      "author": "Shulaev V.",
      "year": "1995",
      "unstructured": "Shulaev V., Leon J., Raskin I., ibid. 7, 1691 (1995).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_102_2",
      "doi-asserted-by": "crossref",
      "unstructured": "S. A. Bowling et al. ibid. 6 1845 (1994).",
      "DOI": "10.2307/3869912"
    },
    {
      "key": "e_1_3_1_103_2",
      "unstructured": "H. Cao S. A. Bowling A. S. Gordon X. Dong ibid. p. 1583."
    },
    {
      "key": "e_1_3_1_104_2",
      "doi-asserted-by": "crossref",
      "first-page": "6602",
      "DOI": "10.1073/pnas.92.14.6602",
      "volume": "92",
      "author": "Delaney T.",
      "year": "1995",
      "unstructured": "Delaney T., Friedrich L., Ryals J., Proc. Natl. Acad. Sci. U.S.A. 92, 6602 (1995).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_105_2",
      "unstructured": "K. S. Century E. B. Holub B. J. Staskawicz ibid. p. 6597."
    },
    {
      "key": "e_1_3_1_106_2",
      "first-page": "2033",
      "volume": "8",
      "author": "Parker J. E.",
      "year": "1996",
      "unstructured": "Parker J. E., et al., Plant Cell 8, 2033 (1996).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_107_2",
      "first-page": "983",
      "volume": "6",
      "author": "Freialdenhoven A.",
      "year": "1994",
      "unstructured": "Freialdenhoven A., et al., ibid. 6, 983 (1994).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_108_2",
      "unstructured": "K. E. Hammond-Kosack D. A. Jones J. D. G. Jones ibid. p. 361."
    },
    {
      "key": "e_1_3_1_109_2",
      "doi-asserted-by": "crossref",
      "first-page": "4189",
      "DOI": "10.1073/pnas.92.10.4189",
      "volume": "92",
      "author": "Ausubel F. M.",
      "year": "1995",
      "unstructured": "Ausubel F. M., Katagiri F., Mindrinos M., Glazebrook J., Proc. Natl. Acad. Sci. U.S.A. 92, 4189 (1995).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_110_2",
      "first-page": "8955",
      "volume": "91",
      "author": "Glazebrook J.",
      "year": "1994",
      "unstructured": "Glazebrook J., Ausubel F. M., ibid. 91, 8955 (1994).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_111_2",
      "unstructured": "T. J. Pryor and J. Ellis Adv. Plant Pathol. 10 281 (1993)."
    },
    {
      "key": "e_1_3_1_112_2",
      "unstructured": "W.-Y. Song and P. C. Ronald in preparation."
    },
    {
      "key": "e_1_3_1_113_2",
      "doi-asserted-by": "crossref",
      "first-page": "373",
      "DOI": "10.1093/genetics/141.1.373",
      "volume": "141",
      "author": "Richter T. E.",
      "year": "1995",
      "unstructured": "Richter T. E., Pryor T. J., Bennetzen J. L., Hulbert S. H., Genetics 141, 373 (1995).",
      "journal-title": "Genetics"
    },
    {
      "key": "e_1_3_1_114_2",
      "unstructured": "S. Whitham and B. Baker unpublished data."
    },
    {
      "key": "e_1_3_1_115_2",
      "doi-asserted-by": "crossref",
      "first-page": "371",
      "DOI": "10.1146/annurev.ge.29.120195.002103",
      "volume": "29",
      "author": "Morisato D.",
      "year": "1995",
      "unstructured": "Morisato D., Anderson K. V., Annu. Rev. Genet. 29, 371 (1995).",
      "journal-title": "Annu. Rev. Genet."
    },
    {
      "key": "e_1_3_1_116_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.9.22.2723"
    },
    {
      "key": "e_1_3_1_117_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.271.5252.1128"
    },
    {
      "key": "e_1_3_1_118_2",
      "doi-asserted-by": "crossref",
      "first-page": "515",
      "DOI": "10.1016/0092-8674(93)90071-W",
      "volume": "72",
      "author": "Shelton C. A.",
      "year": "1993",
      "unstructured": "Shelton C. A., Wasserman S. A., Cell 72, 515 (1993).",
      "journal-title": "Cell"
    },
    {
      "key": "e_1_3_1_119_2",
      "first-page": "753",
      "volume": "75",
      "author": "Ip Y. T.",
      "year": "1993",
      "unstructured": "Ip Y. T., et al., ibid. 75, 753 (1993).",
      "journal-title": "ibid."
    },
    {
      "key": "e_1_3_1_120_2",
      "doi-asserted-by": "crossref",
      "unstructured": "B. Lamaitre E. Nicolas L. Michaut J.-M. Reichhart J. A. Hoffmann ibid. 86 973 (1996).",
      "DOI": "10.1016/S0092-8674(00)80172-5"
    },
    {
      "key": "e_1_3_1_121_2",
      "doi-asserted-by": "crossref",
      "first-page": "4175",
      "DOI": "10.1073/pnas.92.10.4175",
      "volume": "92",
      "author": "Dinesh-Kumar S. P.",
      "year": "1995",
      "unstructured": "Dinesh-Kumar S. P., et al., Proc. Natl. Acad. Sci. U.S.A. 92, 4175 (1995).",
      "journal-title": "Proc. Natl. Acad. Sci. U.S.A."
    },
    {
      "key": "e_1_3_1_122_2",
      "unstructured": "S. E. Clark R. W. Williams E. M. Meyerowitz unpublished data."
    },
    {
      "key": "e_1_3_1_123_2",
      "first-page": "735",
      "volume": "8",
      "author": "Torii K. U.",
      "year": "1996",
      "unstructured": "Torii K. U., et al., Plant Cell 8, 735 (1996).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "e_1_3_1_124_2",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1016/0962-8924(91)90072-H",
      "volume": "1",
      "author": "Schreck R.",
      "year": "1991",
      "unstructured": "Schreck R., Baeuerle P. A., Trends Cell Biol. 1, 39 (1991).",
      "journal-title": "Trends Cell Biol."
    },
    {
      "key": "e_1_3_1_125_2",
      "doi-asserted-by": "crossref",
      "first-page": "2005",
      "DOI": "10.1002/j.1460-2075.1993.tb05850.x",
      "volume": "12",
      "author": "Meyer M.",
      "year": "1993",
      "unstructured": "Meyer M., Schreck R., Baeuerle P. A., EMBO J. 12, 2005 (1993).",
      "journal-title": "EMBO J."
    },
    {
      "key": "e_1_3_1_126_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.8052854"
    },
    {
      "key": "e_1_3_1_127_2",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1016/0966-842X(93)90087-8",
      "volume": "1",
      "author": "Van Gijsegem F.",
      "year": "1993",
      "unstructured": "Van Gijsegem F., Genin S., Boucher C., Trends Microbiol. 1, 175 (1993).",
      "journal-title": "Trends Microbiol."
    },
    {
      "key": "e_1_3_1_128_2",
      "unstructured": "H.-C. Huang R.-W. Lin C.-J. Chang A. Collmer W.-L. Deng Mol. Plant-Microbe Interact. 8 733 (1995)."
    },
    {
      "key": "e_1_3_1_129_2",
      "doi-asserted-by": "crossref",
      "first-page": "681",
      "DOI": "10.1046/j.1365-2958.1996.5731077.x",
      "volume": "20",
      "author": "Bogdanove A. J.",
      "year": "1996",
      "unstructured": "Bogdanove A. J., et al., Mol. Microbiol. 20, 681 (1996).",
      "journal-title": "Mol. Microbiol."
    },
    {
      "key": "e_1_3_1_130_2",
      "unstructured": "E. C. Oerke H. W. Dehne F. Schonbeck A. Weber Crop Production and Crop Protection. Estimated Losses in Major Food and Cash Crops (Elsevier New York 1994)."
    },
    {
      "key": "e_1_3_1_131_2",
      "doi-asserted-by": "crossref",
      "first-page": "205",
      "DOI": "10.1016/S0959-437X(05)80275-8",
      "volume": "2",
      "author": "Alber T.",
      "year": "1992",
      "unstructured": "Alber T., Curr. Opin. Genet. Dev. 2, 205 (1992).",
      "journal-title": "Curr. Opin. Genet. Dev."
    },
    {
      "key": "e_1_3_1_132_2",
      "doi-asserted-by": "crossref",
      "first-page": "9",
      "DOI": "10.1111/j.1432-1033.1994.tb18835.x",
      "volume": "222",
      "author": "Traut T. W.",
      "year": "1994",
      "unstructured": "Traut T. W., Eur. J. Biochem. 222, 9 (1994).",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "e_1_3_1_133_2",
      "doi-asserted-by": "crossref",
      "first-page": "355",
      "DOI": "10.1038/351355b0",
      "volume": "351",
      "author": "Gay N. J.",
      "year": "1991",
      "unstructured": "Gay N. J., Keith F. J., Nature 351, 355 (1991).",
      "journal-title": "Nature"
    },
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      "key": "e_1_3_1_134_2",
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      "first-page": "105",
      "DOI": "10.1016/0022-2836(82)90515-0",
      "volume": "157",
      "author": "Kyte J.",
      "year": "1982",
      "unstructured": "Kyte J., Doolittle R. F., J. Mol. Biol. 157, 105 (1982).",
      "journal-title": "J. Mol. Biol."
    },
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