Abstract
Guanine nucleotide-binding proteins (G proteins) transduce a very large number of cellular regulatory signals. Several recent papers have shown that the larger heterotrimeric G proteins are regulated by a class of molecules known as the RGS proteins (regulators of G protein-signaling family) that are analogous to the GAPs (GTPase activating proteins), which regulate small monomeric G proteins. Iyengar summarizes this evidence and discusses the mechanism of action of the RGS proteins.
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Dates
Type | When |
---|---|
Created | 23 years, 1 month ago (July 27, 2002, 5:50 a.m.) |
Deposited | 1 year, 7 months ago (Jan. 12, 2024, 10:33 p.m.) |
Indexed | 1 year, 7 months ago (Jan. 13, 2024, 12:01 a.m.) |
Issued | 28 years, 7 months ago (Jan. 3, 1997) |
Published | 28 years, 7 months ago (Jan. 3, 1997) |
Published Print | 28 years, 7 months ago (Jan. 3, 1997) |
@article{Iyengar_1997, title={There Are GAPS and There Are GAPS}, volume={275}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.275.5296.42}, DOI={10.1126/science.275.5296.42}, number={5296}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Iyengar, Ravi}, year={1997}, month=jan, pages={42–43} }