DOI: 10.1126/science.272.5264.974. Regulating Cell Proliferation

Regulating Cell Proliferation—As Easy as APC

10.1126/science.272.5264.974

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

A report in this week's issue of Science [Rubinfeld et al. ( p. 1023 )] places the tumor suppressor APC firmly in the signal transduction pathway triggered by WINGLESS (in the fruit fly Drosophila ) and WNT (in the mouse). This pathway is a supremely important one for control of cell fate. A second report [Matsumine et al. (p. 1020)] identifies a new downstream target of APC, another tumor suppressor Drosophila discs large ( dlg ). In his Perspective, Peifer discusses what these findings may mean for how APC participates in cell fate control.

Bibliography

Peifer, M. (1996). Regulating Cell ProliferationâAs Easy as APC. Science, 272(5264), 974â975.

Authors 1

Mark Peifer (first)

References 27 Referenced 52

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Dates

Type	When
Created	18 years, 10 months ago (Oct. 27, 2006, 2:30 p.m.)
Deposited	1 year, 7 months ago (Jan. 12, 2024, 4:43 p.m.)
Indexed	1 year, 7 months ago (Jan. 13, 2024, 12:26 a.m.)
Issued	29 years, 3 months ago (May 17, 1996)
Published	29 years, 3 months ago (May 17, 1996)
Published Print	29 years, 3 months ago (May 17, 1996)

Funders 0

None

BibTeX

@article{Peifer_1996, title={Regulating Cell Proliferation—As Easy as APC}, volume={272}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.272.5264.974}, DOI={10.1126/science.272.5264.974}, number={5264}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Peifer, Mark}, year={1996}, month=may, pages={974–975} }

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