Crossref journal-article
American Association for the Advancement of Science (AAAS)
Science (221)
Abstract

Specific messenger RNAs (mRNAs) can be sequestered within distinct cellular locations, but little is known about how this is accomplished. The participation of the three major cellular filaments in the localization of actin mRNA was studied in chicken embryo fibroblasts. Movement of actin mRNA to the cell periphery and maintenance of that regionalization required intact microfilaments (composed of actin) but not microtubules or intermediate filaments. The results presented here suggest that actin-binding proteins may participate in mRNA sorting.

Bibliography

Sundell, C. L., & Singer, R. H. (1991). Requirement of Microfilaments in Sorting of Actin Messenger RNA. Science, 253(5025), 1275–1277.

Authors 2
  1. Cynthia L. Sundell (first)
  2. Robert H. Singer (additional)
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Dates
Type When
Created 18 years, 10 months ago (Oct. 5, 2006, 2:10 p.m.)
Deposited 1 year, 7 months ago (Jan. 11, 2024, 11:48 a.m.)
Indexed 1 month, 3 weeks ago (July 7, 2025, 2:02 a.m.)
Issued 33 years, 11 months ago (Sept. 13, 1991)
Published 33 years, 11 months ago (Sept. 13, 1991)
Published Print 33 years, 11 months ago (Sept. 13, 1991)
Funders 0

None

@article{Sundell_1991, title={Requirement of Microfilaments in Sorting of Actin Messenger RNA}, volume={253}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1891715}, DOI={10.1126/science.1891715}, number={5025}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Sundell, Cynthia L. and Singer, Robert H.}, year={1991}, month=sep, pages={1275–1277} }