DOI: 10.1126/science.177.4055.1196. Nucleated Assembly of Microtubules in Porcine Brain Extracts

Nucleated Assembly of Microtubules in Porcine Brain Extracts

10.1126/science.177.4055.1196

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Disk-type structures found in extracts of porcine brain tissue appear to be required for microtubule assembly in vitro. From the morphology of the disks and the dependence of microtubule assembly on the presence of these structures, we propose that the disks are nucleation centers for the polymerization of microtubule protein.

Bibliography

Borisy, G. G., & Olmsted, J. B. (1972). Nucleated Assembly of Microtubules in Porcine Brain Extracts. Science, 177(4055), 1196â1197.

Authors 2

Gary G. Borisy (first)
Joanne B. Olmsted (additional)

References 10 Referenced 214

Borisy, G. G., Proceedings of the National Academy of Sciences of the United States of America 69: 2890 (1972). / Proceedings of the National Academy of Sciences of the United States of America (1972)
BORISY, G.G., AGGREGATION OF MICROTUBULE PROTEIN IN-VITRO, JOURNAL OF CELL BIOLOGY 47: A22 (1970). / JOURNAL OF CELL BIOLOGY (1970)
DURHAM, ACH, STATES OF AGGREGATION OF TOBACCO MOSAIC VIRUS PROTEIN, NATURE-NEW BIOLOGY 229: 37 (1971). / NATURE-NEW BIOLOGY (1971)
INOUE, S, CELL MOTILITY BY LABILE ASSOCIATION OF MOLECULES - NATURE OF MITOTIC SPINDLE FIBERS AND THEIR ROLE IN CHROMOSOME MOVEMENT, JOURNAL OF GENERAL PHYSIOLOGY 50: 259 (1967). (10.1085/jgp.50.6.259) / JOURNAL OF GENERAL PHYSIOLOGY (1967)
OKADA, Y, ASSEMBLY MECHANISM OF TOBACCO MOSAIC VIRUS PARTICLE FROM ITS RIBONUCLEIC-ACID AND PROTEIN, MOLECULAR AND GENERAL GENETICS 114: 205 (1972). (10.1007/BF01788889) / MOLECULAR AND GENERAL GENETICS (1972)
OOSAWA, F, PRINCIPLES BIOMOLECU: 273 (1966). / PRINCIPLES BIOMOLECU (1966)
PORTER, K.R., PRINCIPLES BIOMOLECU: 308 (1966). / PRINCIPLES BIOMOLECU (1966)
RICHARDS, K.E., ASSEMBLY OF TOBACCO MOSAIC VIRUS IN-VITRO - EFFECT OF STATE OF POLYMERIZATION OF PROTEIN COMPONENT, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 69: 1121 (1972). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1972)
STEPHENS, R.E., REASSOCIATION OF MICROTUBULE PROTEIN, JOURNAL OF MOLECULAR BIOLOGY 33: 517 (1968). (10.1016/0022-2836(68)90210-6) / JOURNAL OF MOLECULAR BIOLOGY (1968)
10.1126/science.177.4054.1104

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 10:03 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 9:08 a.m.)
Indexed	1 month, 4 weeks ago (July 4, 2025, 12:15 a.m.)
Issued	52 years, 11 months ago (Sept. 29, 1972)
Published	52 years, 11 months ago (Sept. 29, 1972)
Published Print	52 years, 11 months ago (Sept. 29, 1972)

Funders 0

None

BibTeX

@article{Borisy_1972, title={Nucleated Assembly of Microtubules in Porcine Brain Extracts}, volume={177}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.177.4055.1196}, DOI={10.1126/science.177.4055.1196}, number={4055}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Borisy, Gary G. and Olmsted, Joanne B.}, year={1972}, month=sep, pages={1196–1197} }

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