DOI: 10.1126/science.175.4017.84. Olfactory Bulb Units: Activity Correlated with Inhalation Cycles and Odor Quality

Olfactory Bulb Units: Activity Correlated with Inhalation Cycles and Odor Quality

10.1126/science.175.4017.84

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Single olfactory bulb units were studied in two macrosmatic species of rodents under conditions intended to preserve the cyclical stimulation which normally accompanies nasal breathing. Patterns of unit activity related to the inhalation cycle were observed in all animals, often in the absence of specific stimuli, and could not be explained in simple mechanical terms. Distinctive changes in these patterns occurred in response to certain odors, and were generally independent of changes in the overall firing frequency. These findings indicate that a change in the overall firing frequency of unit discharges is neither a necessary nor sufficient measure of responsiveness to odors in the rodent olfactory bulb, and that stimulus-specific temporal distributions of unit firing may be involved in olfacto-endocrine activities.

Bibliography

Macrides, F., & Chorover, S. L. (1972). Olfactory Bulb Units: Activity Correlated with Inhalation Cycles and Odor Quality. Science, 175(4017), 84â87.

Authors 2

Foteos Macrides (first)
Stephan L. Chorover (additional)

References 34 Referenced 231

BEACH, F.A., RESPONSE OF MALE DOGS TO URINE FROM FEMALES IN HEAT, JOURNAL OF MAMMALOGY 30: 391 (1949). (10.2307/1375215) / JOURNAL OF MAMMALOGY (1949)
BRONSON, F.H., PERSPECTIVES REPRODU: 102 (1968). / PERSPECTIVES REPRODU (1968)
BRUCE, H.M., BRITISH MEDICAL BULLETIN 25: 10 (1970). / BRITISH MEDICAL BULLETIN (1970)
10.1126/science.157.3787.457
CARR, W.J., RESPONSES OF RATS TO SEX ODORS, JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 59: 370 (1965). (10.1037/h0022036) / JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY (1965)
CLULOW, F.V., NATURE 219: 611 (1968). (10.1038/219611a0) / NATURE (1968)
10.1126/science.137.3532.764
10.1126/science.171.3967.210
HEIMER, L, SYNAPTIC DISTRIBUTION OF CENTRIPETAL AND CENTRIFUGAL NERVE FIBRES IN OLFACTORY SYSTEM OF RAT . AN EXPERIMENTAL ANATOMICAL STUDY, JOURNAL OF ANATOMY 103: 413 (1968). / JOURNAL OF ANATOMY (1968)
HINDS, J.W., RECIPROCAL AND SERIAL DENDRODENDRITIC SYNAPSES IN GLOMERULAR LAYER OF RAT OLFACTORY BULB, BRAIN RESEARCH 17: 530 (1970). (10.1016/0006-8993(70)90263-5) / BRAIN RESEARCH (1970)
ILSE, D.R., BR J ANIM BEHAV 3: 118 (1955). (10.1016/S0950-5601(55)80003-2) / BR J ANIM BEHAV (1955)
LINDSEY, D.R., IMPORTANCE OF OLFACTORY STIMULI IN MATING BEHAVIOUR OF RAM, ANIMAL BEHAVIOUR 13: 75 (1965). (10.1016/0003-3472(65)90074-6) / ANIMAL BEHAVIOUR (1965)
LOHMAN, AHM, ACTA ANAT S 53: 49 (1963). / ACTA ANAT S (1963)
LOHMAN, AHM, PROGRESS IN BRAIN RESEARCH 3: 149 (1963). (10.1016/S0079-6123(08)60571-3) / PROGRESS IN BRAIN RESEARCH (1963)
10.1126/science.144.3625.1469
MICHAEL, R.P., PHEROMONES IN COMMUNICATION OF SEXUAL STATUS IN PRIMATES, NATURE 218: 746 (1968). (10.1038/218746a0) / NATURE (1968)
MONTAGNA, W, SKIN OF LEMURS, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 102: 190 (1962). (10.1111/j.1749-6632.1962.tb13639.x) / ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (1962)
MOULTON, D.G., ELECTROPHYSIOLOGY OF OLFACTORY SYSTEM, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 116: 380 (1964). (10.1111/j.1749-6632.1964.tb45071.x) / ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (1964)
10.1126/science.167.3916.302
MYKTOWYCZ, R, ANIM BEHAV 13: 400 (1965). (10.1016/0003-3472(65)90097-7) / ANIM BEHAV (1965)
Mykytowycz, R., Nature 193:799 (1962). / Nature (1962)
10.1126/science.134.3485.1049
PFAFF, D.W., OLFACTORY AND HORMONAL INFLUENCES ON BASAL FORE-BRAIN OF MALE RAT, BRAIN RESEARCH 15: 137 (1969). (10.1016/0006-8993(69)90315-1) / BRAIN RESEARCH (1969)
PHILLIPS, C.G., RESPONSES OF MITRAL CELLS TO STIMULATION OF LATERAL OLFACTORY TRACT IN RABBIT, JOURNAL OF PHYSIOLOGY-LONDON 168: 65 (1963). (10.1113/jphysiol.1963.sp007178) / JOURNAL OF PHYSIOLOGY-LONDON (1963)
PRICE, J.L., ORIGIN OF CENTRIFUGAL FIBRES TO OLFACTORY BULB, BRAIN RESEARCH 14: 542 (1969). (10.1016/0006-8993(69)90135-8) / BRAIN RESEARCH (1969)
PRICE, J.L., AN EXPERIMENTAL STUDY OF ORIGIN AND COURSE OF CENTRIFUGAL FIBRES TO OLFACTORY BULB IN RAT, JOURNAL OF ANATOMY 107: 215 (1970). / JOURNAL OF ANATOMY (1970)
PRICE, J.L., SYNAPTOLOGY OF GRANULE CELLS OF OLFACTORY BULB, JOURNAL OF CELL SCIENCE 7: 125 (1970). (10.1242/jcs.7.1.125) / JOURNAL OF CELL SCIENCE (1970)
RALL, W, DENDRODENDRITIC SYNAPTIC PATHWAY FOR INHIBITION IN OLFACTORY BULB, EXPERIMENTAL NEUROLOGY 14: 44 (1966). (10.1016/0014-4886(66)90023-9) / EXPERIMENTAL NEUROLOGY (1966)
10.1126/science.160.3826.432
THOMAS, R.C., PRECISE LOCALIZATION OF RENSHAW CELLS WITH A NEW MARKING TECHNIQUE, NATURE 206: 211 (1965). / NATURE (1965)
VALVERDE, F, STUDIES PIRIFORM LOB: 50 (1965). / STUDIES PIRIFORM LOB (1965)
WALSH, R.R., SINGLE CELL SPIKE ACTIVITY IN THE OLFACTORY BULB, AMERICAN JOURNAL OF PHYSIOLOGY 186: 255 (1956). (10.1152/ajplegacy.1956.186.2.255) / AMERICAN JOURNAL OF PHYSIOLOGY (1956)
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10.1126/science.161.3841.584

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 10:03 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 10:31 a.m.)
Indexed	3 weeks, 3 days ago (Aug. 6, 2025, 8:12 a.m.)
Issued	53 years, 7 months ago (Jan. 7, 1972)
Published	53 years, 7 months ago (Jan. 7, 1972)
Published Print	53 years, 7 months ago (Jan. 7, 1972)

Funders 0

None

BibTeX

@article{Macrides_1972, title={Olfactory Bulb Units: Activity Correlated with Inhalation Cycles and Odor Quality}, volume={175}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.175.4017.84}, DOI={10.1126/science.175.4017.84}, number={4017}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Macrides, Foteos and Chorover, Stephan L.}, year={1972}, month=jan, pages={84–87} }

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