DOI: 10.1126/science.174.4010.709. Mammalian Motor Units: Physiological-Histochemical Correlation in Three Types in Cat Gastrocnemius

Mammalian Motor Units: Physiological-Histochemical Correlation in Three Types in Cat Gastrocnemius

10.1126/science.174.4010.709

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The correlation among a variety of physiological properties and the histochemical characteristics of muscle fibers belonging to single motor units in a mixed mammalian muscle is directly demonstrated. The population of motor units making up the cat gastrocnemius was classified into three nonoverlapping groups on the basis of a combination of physiological parameters. The muscle fibers belonging to motor units of each physiological type exhibited a distinctive histochemical profile, such that the three basic histochemical "fiber types" exactly matched the three physiologically defined groups. Within each individual motor unit, the muscle fibers were histochemically uniform.

Bibliography

Burke, R. E., Levine, D. N., Zajac, F. E., Tsairis, P., & Engel, W. K. (1971). Mammalian Motor Units: Physiological-Histochemical Correlation in Three Types in Cat Gastrocnemius. Science, 174(4010), 709â712.

Authors 5

R. E. Burke (first)
D. N. Levine (additional)
F. E. Zajac (additional)
P. Tsairis (additional)
W. K. Engel (additional)

References 24 Referenced 566

BARNARD, R.J., HISTOCHEMICAL, BIOCHEMICAL, AND CONTRACTILE PROPERTIES OF RED, WHITE, AND INTERMEDIATE FIBERS, AMERICAN JOURNAL OF PHYSIOLOGY 220: 410 (1971). (10.1152/ajplegacy.1971.220.2.410) / AMERICAN JOURNAL OF PHYSIOLOGY (1971)
BRANDSTATER, M.E., BULLETIN OF THE AMERICAN ASSOCIATION OF ELECTROMYOGRAPHY AND ELECTRODIAGNOSIS 15: 82 (1969). / BULLETIN OF THE AMERICAN ASSOCIATION OF ELECTROMYOGRAPHY AND ELECTRODIAGNOSIS (1969)
BROOKE, M.H., SOME COMMENTS ON HISTOCHEMICAL CHARACTERIZATION OF MUSCLE ADENOSINE TRIPHOSPHATASE, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 17: 431 (1969). (10.1177/17.6.431) / JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (1969)
BURKE, R.E., MOTOR UNIT TYPES OF CAT TRICEPS SURAE MUSCLE, JOURNAL OF PHYSIOLOGY-LONDON 193: 141 (1967). (10.1113/jphysiol.1967.sp008348) / JOURNAL OF PHYSIOLOGY-LONDON (1967)
BURKE, R.E., FIRING PATTERNS OF GASTROCNEMIUS MOTOR UNITS IN DECEREBRATE CAT, JOURNAL OF PHYSIOLOGY-LONDON 196: 631 (1968). (10.1113/jphysiol.1968.sp008527) / JOURNAL OF PHYSIOLOGY-LONDON (1968)
BURKE, R.E., A COMPARISON OF PERIPHERAL AND RUBROSPINAL SYNAPTIC INPUT TO SLOW AND FAST TWITCH MOTOR UNITS OF TRECEPS SURAE, JOURNAL OF PHYSIOLOGY-LONDON 207: 709 (1970). (10.1113/jphysiol.1970.sp009090) / JOURNAL OF PHYSIOLOGY-LONDON (1970)
10.1126/science.168.3927.122
DENNY-BROWN, D.E., PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON. SERIES B, CONTAINING PAPERS OF A BIOLOGICAL CHARACTER 104: 371 (1929). (10.1098/rspb.1929.0014) / PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON. SERIES B, CONTAINING PAPERS OF A BIOLOGICAL CHARACTER (1929)
DOYLE, A.M., BULLETIN OF THE UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE AND COLLEGE OF PHYSICIANS AND SURGEONS 54: 11 (1969). / BULLETIN OF THE UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE AND COLLEGE OF PHYSICIANS AND SURGEONS (1969)
Drews, G. A., Nature 212:1551 (1966). (10.1038/2121551a0) / Nature (1966)
EDSTROM, L, HISTOCHEMICAL COMPOSITION DISTRIBUTION OF FIBRES AND FATIGUABILITY OF SINGLE MOTOR UNITS - ANTERIOR TIBIAL MUSCLE OF RAT, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 31: 424 (1968). (10.1136/jnnp.31.5.424) / JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (1968)
Engel, W. K., NeurologIcal Diagnostic Techniques: 90 (1966). / NeurologIcal Diagnostic Techniques (1966)
FARBER, E, HISTOCHEMICAL LOCALIZATION OF SPECIFIC OXIDATIVE ENZYMES .1. TETRAZOLIUM STAINS FOR DIPHOSPHOPYRIDINE NUCLEOTIDE DIAPHORASE AND TRIPHOSPHOPYRIDINE NUCLEOTIDE DIAPHORASE, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 4: 254 (1956). (10.1177/4.3.254) / JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (1956)
HENNEMAN, E, RELATIONS BETWEEN STRUCTURE AND FUNCTION IN DESIGN OF SKELETAL MUSCLES, JOURNAL OF NEUROPHYSIOLOGY 28: 581 (1965). (10.1152/jn.1965.28.3.581) / JOURNAL OF NEUROPHYSIOLOGY (1965)
KUGELBERG, E, DIFFERENTIAL HISTOCHEMICAL EFFECTS OF MUSCLE CONTRACTIONS ON PHOSPHORYLASE AND GLYCOGEN IN VARIOUS TYPES OF FIBRES - RELATION TO FATIGUE, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 31: 415 (1968). (10.1136/jnnp.31.5.415) / JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (1968)
McManus, J. F. A., Stalning Methods: Histological IlIId Histochemical: 126 (1960). / Stalning Methods: Histological IlIId Histochemical (1960)
NACHLAS, M.M., CYTOCHEMICAL DEMONSTRATION OF SUCCINIC DEHYDROGENASE BY THE USE OF A NEW PARA-NITROPHENYL SUBSTITUTED DITETRAZOLE, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 5: 420 (1957). (10.1177/5.4.420) / JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (1957)
NYSTROM, B, HISTOCHEMISTRY OF DEVELOPING CAT MUSCLES, ACTA NEUROLOGICA SCANDINAVICA 44: 405 (1968). (10.1111/j.1600-0404.1968.tb05584.x) / ACTA NEUROLOGICA SCANDINAVICA (1968)
OLSON, C.B., A FUNCTIONAL AND HISTOCHEMICAL CHARACTERIZATION OF MOTOR UNITS IN A HETEROGENEOUS MUSCLE (FLEXOR DIGITORUM LONGUS) OF CAT, JOURNAL OF COMPARATIVE NEUROLOGY 128: 475 (1966). (10.1002/cne.901280405) / JOURNAL OF COMPARATIVE NEUROLOGY (1966)
Padykula, H. A., Exploratory Concepts in Muscular Dystrophy and Related Disorders: 117 (1967). / Exploratory Concepts in Muscular Dystrophy and Related Disorders (1967)
PADYKULA, H.A., THE SPECIFICITY OF THE HISTOCHEMICAL METHOD FOR ADENOSINE TRIPHOSPHATASE, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 3: 170 (1955). (10.1177/3.3.170) / JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (1955)
ROMANUL, FCA, CAPILLARY SUPPLY AND METABOLISM OF MUSCLE FIBERS, ARCHIVES OF NEUROLOGY 12: 497 (1965). (10.1001/archneur.1965.00460290053007) / ARCHIVES OF NEUROLOGY (1965)
SHERRINGTON, C, Ferrier lecture - Some functional problems attaching to convergence, PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-CONTAINING PAPERS OF A BIOLOGICAL CHARACTER 105: 332 (1929). (10.1098/rspb.1929.0047) / PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-CONTAINING PAPERS OF A BIOLOGICAL CHARACTER (1929)
STEIN, J.M., HISTOCHEMICAL CLASSIFICATION OF INDIVIDUAL SKELETAL MUSCLE FIBERS OF RAT, AMERICAN JOURNAL OF ANATOMY 110: 103 (1962). (10.1002/aja.1001100203) / AMERICAN JOURNAL OF ANATOMY (1962)

Dates

Type	When
Created	18 years, 11 months ago (Oct. 5, 2006, 9:17 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 9:46 a.m.)
Indexed	3 days, 1 hour ago (Sept. 4, 2025, 10:14 a.m.)
Issued	53 years, 9 months ago (Nov. 12, 1971)
Published	53 years, 9 months ago (Nov. 12, 1971)
Published Print	53 years, 9 months ago (Nov. 12, 1971)

Funders 0

None

BibTeX

@article{Burke_1971, title={Mammalian Motor Units: Physiological-Histochemical Correlation in Three Types in Cat Gastrocnemius}, volume={174}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.174.4010.709}, DOI={10.1126/science.174.4010.709}, number={4010}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Burke, R. E. and Levine, D. N. and Zajac, F. E. and Tsairis, P. and Engel, W. K.}, year={1971}, month=nov, pages={709–712} }

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        12
      ]
    ]
  },
  "references-count": 24,
  "journal-issue": {
    "issue": "4010",
    "published-print": {
      "date-parts": [
        [
          1971,
          11,
          12
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1126/science.174.4010.709"
  ],
  "URL": "http://dx.doi.org/10.1126/science.174.4010.709",
  "relation": {},
  "ISSN": [
    "0036-8075",
    "1095-9203"
  ],
  "subject": [],
  "container-title-short": "Science",
  "published": {
    "date-parts": [
      [
        1971,
        11,
        12
      ]
    ]
  }
}