DOI: 10.1126/science.171.3971.577. Specialization of Rabbit Reticulocyte Transfer RNA Content for Hemoglobin Synthesis

Specialization of Rabbit Reticulocyte Transfer RNA Content for Hemoglobin Synthesis

10.1126/science.171.3971.577

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The amount of acceptance of each amino acid per absorbancy unit of rabbit reticulocyte transfer RNA was determined. The results were compared with the amino acid composition of rabbit hemoglobin and with a similar determination of the transfer RNA content of rabbit liver. The histidine and isoleucine transfer RNA content of reticulocytes is specialized for the synthesis of hemoglobin, in which histidine is unusually common and isoleucine unusually scarce compared to most proteins.

Bibliography

Smith, D. W. E., & McNamara, A. L. (1971). Specialization of Rabbit Reticulocyte Transfer RNA Content for Hemoglobin Synthesis. Science, 171(3971), 577â579.

Authors 2

David W. E. Smith (first)
Anne L. McNamara (additional)

References 17 Referenced 53

APGAR, J, PURIFICATION OF ALANINE-, VALINE-, HISTIDINE-, AND TYROSINE-ACCEPTOR RIBONUCLEIC ACIDS FROM YEAST, JOURNAL OF BIOLOGICAL CHEMISTRY 237: 796 (1962). (10.1016/S0021-9258(18)60374-6) / JOURNAL OF BIOLOGICAL CHEMISTRY (1962)
BURKA, E.R., CHARACTERISTICS OF RNA DEGRADATION IN ERYTHROID CELL, JOURNAL OF CLINICAL INVESTIGATION 48: 1266 (1969). (10.1172/JCI106092) / JOURNAL OF CLINICAL INVESTIGATION (1969)
DAYHOFF, M.O., ATLAS PROTEIN SEQUEN 4: D37 (1969). / ATLAS PROTEIN SEQUEN (1969)
GAREL, J.P., FUNCTIONAL ADAPTATION OF TRNAS TO FIBROIN BIOSYNTHESIS IN SILKGLAND OF BOMBYX-MORI-L, FEBS LETTERS 7: 327 (1970). (10.1016/0014-5793(70)80196-X) / FEBS LETTERS (1970)
GILBERT, J.M., CELL-FREE HEMOGLOBIN SYNTHESIS .2. CHARACTERISTICS OF TRANSFER RIBONUCLEIC ACID-DEPENDENT ASSAY SYSTEM, JOURNAL OF BIOLOGICAL CHEMISTRY 245: 2342 (1970). (10.1016/S0021-9258(18)63157-6) / JOURNAL OF BIOLOGICAL CHEMISTRY (1970)
HOLLEY, R.W., SIMPLIFIED PROCEDURE FOR PREPARATION OF TYROSINE- AND VALINE-ACCEPTOR FRACTIONS OF YEAST SOLUBLE RIBONUCLEIC ACID, JOURNAL OF BIOLOGICAL CHEMISTRY 236: 200 (1961). (10.1016/S0021-9258(18)64455-2) / JOURNAL OF BIOLOGICAL CHEMISTRY (1961)
HOUSMAN, D, INITIATION OF HAEMOGLOBIN SYNTHESIS BY METHIONYL-TRNA, NATURE 227: 913 (1970). (10.1038/227913a0) / NATURE (1970)
ITANO, H.A., ABNORMAL HEMOGLOBINS: 3 (1965). / ABNORMAL HEMOGLOBINS (1965)
JACKSON, R, ROLE OF METHIONINE IN INITIATION OF HAEMOGLOBIN SYNTHESIS, NATURE 227: 672 (1970). (10.1038/227672a0) / NATURE (1970)
KUO, T.H., ACCEPTOR ACTIVITY OF 2 MODIFICATIONS OF ALANINE TRANSFER RNA FROM YEAST, FEDERATION PROCEEDINGS 27: 341 (1968). / FEDERATION PROCEEDINGS (1968)
LANKS, K.W., BIOCHEM BIOPHYS RES 40: 710 (1970). / BIOCHEM BIOPHYS RES (1970)
MAENPAA, P.H., QUANTITATIVE VARIATION IN SERINE TRANSFER RIBONUCLEIC ACID DURING ESTROGEN-INDUCED PHOSPHOPROTEIN SYNTHESIS IN ROOSTER LIVER, BIOCHEMISTRY 8: 4926 (1969). (10.1021/bi00840a041) / BIOCHEMISTRY (1969)
RABINOVITZ, M, TRANSLATIONAL CONTROL IN HEMOGLOBIN SYNTHESIS, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 34: 567 (1969). (10.1101/SQB.1969.034.01.064) / COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (1969)
RAHAMINOFF, H, INITIATION OF HAEMOGLOBIN SYNTHESIS IN RABBIT RETICULOCYTES, BIOCHEMICAL JOURNAL 115: 113 (1969). (10.1042/bj1150113) / BIOCHEMICAL JOURNAL (1969)
SHAFRITZ, D.A., FACTOR DEPENDENT BINDING OF METHIONYL-TRNAS TO RETICULOCYTE RIBOSOMES, NATURE 227: 918 (1970). (10.1038/227918a0) / NATURE (1970)
SMITH, DWE, FRACTIONATION OF SOLUBLE RIBONUCLEIC ACID ON DIETHYLAMINOETHYL SEPHADEX WITH A PH AND SALT GRADIENT FOR ELUTION, JOURNAL OF BIOLOGICAL CHEMISTRY 241: 4487 (1966). (10.1016/S0021-9258(18)99746-2) / JOURNAL OF BIOLOGICAL CHEMISTRY (1966)
TRISTRAM, G.R., PROTEINS CHEM BIOL A 1: 181 (1953). / PROTEINS CHEM BIOL A (1953)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 9:17 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 11:23 a.m.)
Indexed	15 hours, 54 minutes ago (Sept. 4, 2025, 9:59 a.m.)
Issued	54 years, 6 months ago (Feb. 12, 1971)
Published	54 years, 6 months ago (Feb. 12, 1971)
Published Print	54 years, 6 months ago (Feb. 12, 1971)

Funders 0

None

BibTeX

@article{Smith_1971, title={Specialization of Rabbit Reticulocyte Transfer RNA Content for Hemoglobin Synthesis}, volume={171}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.171.3971.577}, DOI={10.1126/science.171.3971.577}, number={3971}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Smith, David W. E. and McNamara, Anne L.}, year={1971}, month=feb, pages={577–579} }

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